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FDA Approves Fostamatinib for ITP After Insufficient Response to Previous Treatment

FDA Approves Fostamatinib for ITP After Insufficient Response to Previous Treatment

The US FDA granted approval to fostamatinib (Tavalisse), a kinase inhibitor, for the treatment of thrombocytopenia in patients with chronic IPT who have had an insufficient response to a previous treatment.

Elderly Patients Are Underrepresented in Trials For Soft Tissue Sarcoma

Elderly Patients Are Underrepresented in Trials For Soft Tissue Sarcoma

With median age of participants in clinical trials for soft-tissue sarcoma younger than most patients who develop the disease, these researchers sought to determine the prevalence of including persons older than 65 in clinical trials and the efficacy of first-line chemotherapy for STS in older patients.

Combination Effective as First-Line Therapy in Advanced ER-Positive HER2-Negative Breast Cancer

Combination Effective as First-Line Therapy in Advanced ER-Positive HER2-Negative Breast Cancer

In this open label phase 2 BOLERO-4 study, researchers evaluated the effect of everolimus plus endocrine therapy on progression-free survival.

In Older Women With Breast Cancer QoL May Predict 10-Year Mortality

In Older Women With Breast Cancer QoL May Predict 10-Year Mortality

A model that incorporates HRQOL was found to outperform a model that only employs traditional prognostic variables.

Screening Colonoscopy Improves CRC-Related Mortality in Veterans

Screening Colonoscopy Improves CRC-Related Mortality in Veterans

Researchers conducted a case-control study to determine whether colonoscopy is associated with decreased CRC mortality in veterans and whether its effect differs by anatomical location of CRC.

Progression-Free Survival Extended With PANEX Protocol in R/R Multiple Myeloma

Progression-Free Survival Extended With PANEX Protocol in R/R Multiple Myeloma

This treatment-expansion study evaluated the tolerability and safety of the PANEX (panobinostat plus bortezomib with dexamethasone) protocol in heavily treated patients with R/R multiple myeloma.

National Cancer Drug Shortages Unknown to Many Patients

National Cancer Drug Shortages Unknown to Many Patients

A majority of study respondents reported wanting to be informed about the differences in a drug substitution's efficacy or side effects.

Physical Inactivity Linked With Increased Risk of Hodgkin, Non-Hodgkin Lymphoma

Physical Inactivity Linked With Increased Risk of Hodgkin, Non-Hodgkin Lymphoma

In a case-control study using PEDS data, researchers determined the impact of inactivity on risk for Hodgkin lymphoma and non-Hodgkin lymphoma.

Following ACS Guidelines Shown to Improve Outcomes for Colon Cancer Survivors

Following ACS Guidelines Shown to Improve Outcomes for Colon Cancer Survivors

A prospective study assessing the outcomes of a cohort of participants in the CALGB 89803 study determined the effect of following the American Cancer Society guidelines on survival for persons with colon cancer.

Pivot Nurse Improves Patients' Navigation Through Lung Cancer Care

Pivot Nurse Improves Patients' Navigation Through Lung Cancer Care

Researchers in Montreal presented results of a study on the effects of using a pivot nurse in oncology (PNO) on continuity of care, outcomes, and quality of life for patients with lung cancer at the 2018 European Lung Cancer Congress.

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