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Factors Affecting Employment Participation in Early-stage Breast Cancer

Factors Affecting Employment Participation in Early-stage Breast Cancer

Researchers conducted a multivariate analysis to determine the factors that contribute to employment participation among women with early-stage breast cancer.

Cachexia Not Improved With Celecoxib Plus Megestrol vs Megestrol Alone

Cachexia Not Improved With Celecoxib Plus Megestrol vs Megestrol Alone

Double-blind phase 3 study evaluated the effect of megestrol combined with celecoxib vs monotherapy on cachexia in patients with gastrointestinal cancer.

Gas Mixture Improves Efficacy of Breakthrough Cancer Pain Treatment

Gas Mixture Improves Efficacy of Breakthrough Cancer Pain Treatment

Patient self-administration of a nitrous oxide/oxygen combination appears to be superior to oxygen alone as an adjunct analgesic treatment for severe breakthrough cancer pain.

Chemotherapy-Related Fatigue Linked to Levothyroxine Use in Breast Cancer

Chemotherapy-Related Fatigue Linked to Levothyroxine Use in Breast Cancer

In a secondary analysis of the BEATE and INVEST study, researchers followed a link between levothyroxine use, exercise, and fatigue in women with breast cancer undergoing chemotherapy.

Obesity, Male Gender May Improve Survival Outcomes with Targeted and Immunotherapy in Melanoma

Obesity, Male Gender May Improve Survival Outcomes with Targeted and Immunotherapy in Melanoma

A retrospective study evaluated the relationship of BMI with survival outcomes among patients with metastatic melanoma who received targeted therapy, immunotherapy, or chemotherapy.

Apalutamide Prolongs Time to Metastasis in Castration-resistant Prostate Cancer

Apalutamide Prolongs Time to Metastasis in Castration-resistant Prostate Cancer

SPARTAN phase 3 study shows that apalutamide prolongs metastasis-free survival and time to symptomatic progression compared with placebo among men with nonmetastatic CRPC.

FDA Upgrades Nivolumab to Regular Approval for Adjuvant Treatment of Advanced Melanoma

FDA Upgrades Nivolumab to Regular Approval for Adjuvant Treatment of Advanced Melanoma

The FDA granted approval for nivolumab for adjuvant treatment of some patients with melanoma, based on the results of the CHECKMATE-238 study.

Self-Predictions for Well-Being Influence Satisfaction After Mastectomy, Breast Reconstruction

Self-Predictions for Well-Being Influence Satisfaction After Mastectomy, Breast Reconstruction

Observational study assessed the influence of patients' self-predictions for well-being after undergoing mastectomy for breast cancer with or without immediate breast reconstruction.

Susceptibility Gene Mutations Common in Those With Pancreatic Cancer and History of Other Cancers

Susceptibility Gene Mutations Common in Those With Pancreatic Cancer and History of Other Cancers

Those with pancreatic adenocarcinoma and a personal history of another cancer associated with hereditary breast and ovarian cancer or Lynch syndrome may be more likely to carry germline mutations.

Axitinib Plus Pembrolizumab Shows Promise in Treatment-Naïve Advanced RCC

Axitinib Plus Pembrolizumab Shows Promise in Treatment-Naïve Advanced RCC

Nonrandomized trial demonstrates tolerability and antitumor activity of a PD-1 checkpoint inhibitor plus a VEGF-TKI in patients with treatment-naïve advanced RCC.

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