Toxicity Similar, But Overall Survival Poor in Cetuximab vs Cisplatin for HPV-Positive Oropharyngeal Cancer

Toxicity Similar, But Overall Survival Poor in Cetuximab vs Cisplatin for HPV-Positive Oropharyngeal Cancer

In a randomized phase 3 trial, researchers sought to determine if cetuximab-based chemoradiotherapy could be a less-toxic alternative to cisplatin-based chemoradiotherapy in patients with HPV-positive oropharyngeal cancer.

Imported Doxorubicin Similar to US FDA-Approved Brand in Relapsed/Refractory Ovarian Cancer

Imported Doxorubicin Similar to US FDA-Approved Brand in Relapsed/Refractory Ovarian Cancer

This retrospective analysis determined the effect of Doxil vs Lipodox brands of doxorubicin, used for the treatment of recurrent or refractory ovarian cancer.

FDA Approves Tagraxofusp, First Approved Treatment for a Rare, Aggressive Hematologic Cancer

FDA Approves Tagraxofusp, First Approved Treatment for a Rare, Aggressive Hematologic Cancer

FDA grants approval to tagraxofusp-erzs (Elzonris), a first treatment for blastic plasmacytoid dentritic cell neoplasm and the first therapy to target CD123.

High Expression of DNA Repair Genes at Diagnosis Predictive of Early Relapse in Pediatric ALL

High Expression of DNA Repair Genes at Diagnosis Predictive of Early Relapse in Pediatric ALL

A data analysis revealed a genetic predictor of relapse for pediatric patients with ALL.

Adjuvant Radiation Therapy Improved Outcomes for Some With Advanced Head and Neck CSCC

Adjuvant Radiation Therapy Improved Outcomes for Some With Advanced Head and Neck CSCC

Researchers determined the 5-year overall and disease-free survival for patients with CSCC of the head and neck who received adjuvant radiation therapy.

Risk of Therapy-Related MDS, AML Increased by Use of Leukemogenic Chemotherapy Agents

Risk of Therapy-Related MDS, AML Increased by Use of Leukemogenic Chemotherapy Agents

Researchers sought to determine the association between chemotherapy, particularly platinum-based agents, and increased risk of tMDS/AML.

Neoadjuvant FOLFIRINOX a Better Option Than Surgery Plus Adjuvant Therapy in Pancreatic Cancer

Neoadjuvant FOLFIRINOX a Better Option Than Surgery Plus Adjuvant Therapy in Pancreatic Cancer

A decision-analysis was used to determine which treatment of BR/LA PDAC was more efficacious and more cost-effective: neoadjuvant FOLFIRINOX vs surgery with GEM/CAPE vs surgery with gemcitabine.

Radical Prostatectomy vs Active Surveillance: Results of Nearly 3 Decades of Follow-up

Radical Prostatectomy vs Active Surveillance: Results of Nearly 3 Decades of Follow-up

Researchers sought to determine the effect of radical prostatectomy vs watchful waiting on life expectancy in men with prostate cancer.

All-Grade AE Profiles Better Measure of Quality of Life in Metastatic Castration-Naïve Prostate Cancer

All-Grade AE Profiles Better Measure of Quality of Life in Metastatic Castration-Naïve Prostate Cancer

A study evaluating patient vs clinician reports of adverse events reveals which measures provide a more accurate perspective on patient quality of life.

Pilot Study Evaluates Implementation of Web-Based Self-Management Tool for Cancer Patients

Pilot Study Evaluates Implementation of Web-Based Self-Management Tool for Cancer Patients

After implementing a web-based tool for patients with cancer, researchers surveyed healthcare providers involved in the pilot project regarding their thoughts and experiences with the project.

Risk of Advanced Colorectal Neoplasia Higher Among Some Survivors of Hodgkin Lymphoma

Risk of Advanced Colorectal Neoplasia Higher Among Some Survivors of Hodgkin Lymphoma

Researchers present results of an interim analysis of a study on the prevalence of advanced colorectal neoplasia among survivors of Hodgkin lymphoma.

No Benefit Achieved With Cytoreductive Therapy for Essential Thrombocythemia With Nonhigh Risk of Thrombosis

No Benefit Achieved With Cytoreductive Therapy for Essential Thrombocythemia With Nonhigh Risk of Thrombosis

A study with more than 2000 patient-years follow-up, researchers found cytoreductive therapy was not as effective in patients with ET who have lower risk for thrombosis.

Effect of ADCC Shift in Lots of Trastuzumab Could Change Its Biosimilarity to SB3

Effect of ADCC Shift in Lots of Trastuzumab Could Change Its Biosimilarity to SB3

In developing a biosimilar to trastuzumab, researchers discovered a downward shift in ADCC in lots of the reference drug suggesting the 2 drugs may not be completely identical.

Smartphone App Encourages Breast Cancer Survivors to Meet Physical Activity Goals

Smartphone App Encourages Breast Cancer Survivors to Meet Physical Activity Goals

Researchers evaluated the effectiveness of a smartphone app in encouraging breast cancer survivors to meet their posttreatment exercise goals.

HNC Survivors Continue to Experience Chronic Systemic Symptoms at 1 Year or More Posttreatment

HNC Survivors Continue to Experience Chronic Systemic Symptoms at 1 Year or More Posttreatment

Researchers assessed self-reports of chronic systemic symptoms experienced by head and neck cancer survivors at least 1 year posttreatment.

Mini-Pools of IVIG Just as Effective as Standard IVIG in Pediatric Immune Thrombocytopenia

Mini-Pools of IVIG Just as Effective as Standard IVIG in Pediatric Immune Thrombocytopenia

Intravenous immunoglobulin G with plasma from fewer blood donations provides sufficient therapeutic effect for pediatric patients with ITP.

Apixaban Significantly Lowers Risk of Venous Thromboembolism in High-Risk Patients

Apixaban Significantly Lowers Risk of Venous Thromboembolism in High-Risk Patients

A clinical trial demonstrates that apixaban effectively decreases risk of VTE in patients with cancer; however, risk of major bleeding episodes may be higher.

Prostate Cancer Screening, Treatment Information in YouTube Videos Unreliable, Inaccurate

Prostate Cancer Screening, Treatment Information in YouTube Videos Unreliable, Inaccurate

Researchers sought to determine the quality and accuracy of information on prostate cancer disseminated through YouTube videos.

Beliefs About Medicine, Medicine Sensitivity Influence Patient Decisions on Tamoxifen Use

Beliefs About Medicine, Medicine Sensitivity Influence Patient Decisions on Tamoxifen Use

A survey-based study revealed that women with greater concerns regarding tamoxifen and medicine in general are less likely to take the drug as a preventive measure.

Study Determines Preferred Attributes of PI Combination Therapies for R/R Multiple Myeloma

Study Determines Preferred Attributes of PI Combination Therapies for R/R Multiple Myeloma

In this study, researchers sought to determine the preferred treatment attributes of patients with RRMM, and which they are willing to let go in trade-offs.

Presence of Genetic Variants Not Always Predictive of Cancer Risk

Presence of Genetic Variants Not Always Predictive of Cancer Risk

Researchers investigating genotype-phenotype relationships found that clinical manifestations of some diseases do not match the incidence of genetic variants that predict disease risk.

Risk High, Prognosis Poor for Aggressive Squamous Cell Carcinoma in Organ Transplant Recipients

Risk High, Prognosis Poor for Aggressive Squamous Cell Carcinoma in Organ Transplant Recipients

A retrospective study identifies prognoses and risk factors for SCC among solid organ transplant recipients.

Use of Advance Care Plans Insufficient Among Older Patients Undergoing High-Risk Surgery

Use of Advance Care Plans Insufficient Among Older Patients Undergoing High-Risk Surgery

Researchers within a health care system investigated the use of advance care planning among elderly patients undergoing surgery.

Chemoradiotherapy Outcomes Associated With Stage of Small Cell Lung Cancer

Chemoradiotherapy Outcomes Associated With Stage of Small Cell Lung Cancer

A secondary analysis of data from the CONVERT trial compared survival outcomes after chemoradiotherapy for patients with stage I-II vs patients with stage III disease.

Gene Expression-Based Identifier Predicts Risk, Treatment Outcomes for DLBCL Subtype

Gene Expression-Based Identifier Predicts Risk, Treatment Outcomes for DLBCL Subtype

Using a gene expression-based identifier, researchers found a method for discerning patients with DLBCL who may benefit from nonstandard therapies.

Bioimpedance Spectroscopy Associated With Early Detection of Breast Cancer-Related Lymphedema

Bioimpedance Spectroscopy Associated With Early Detection of Breast Cancer-Related Lymphedema

This retrospective study sought to determine if BIS could detect lymphedema in breast cancer survivors after surgery earlier than other volumetric techniques.

Clinician Interaction Scored High, Some Discussion Topics Did Not in Patient Assessment of Quality of Care

Clinician Interaction Scored High, Some Discussion Topics Did Not in Patient Assessment of Quality of Care

In a survey of patients' perceptions, doctor/nurse interactions were rated high; however, some specific topics for discussion were not rated as high.

Incidence of Adverse Effects of Highly Emetogenic Chemotherapy in Breast Cancer

Incidence of Adverse Effects of Highly Emetogenic Chemotherapy in Breast Cancer

A review of data collected from an electronic health record database identified the adverse effects most likely to result in avoidable hospitalizations among patients receiving HECs for breast cancer.

Mechanical Shoulder Integrity Not Compromised After Breast-Conserving Surgery, Radiotherapy

Mechanical Shoulder Integrity Not Compromised After Breast-Conserving Surgery, Radiotherapy

Researchers assessed shoulder mobility after breast-conserving surgery, comparing results after node-negative and node-positive treatment protocols and healthy controls.

Allogeneic BCMA-Directed CAR-T in Multiple Myeloma: Slated to Hit Phase 1 in 2019

Allogeneic BCMA-Directed CAR-T in Multiple Myeloma: Slated to Hit Phase 1 in 2019

The construct from Allogene has been engineered to avoid the serious immune-related complications linked to allogeneic transplantation.

Early Findings Indicate P-BCMA-101 May Be Effective, Tolerable in R/R Multiple Myeloma

Early Findings Indicate P-BCMA-101 May Be Effective, Tolerable in R/R Multiple Myeloma

Early results of phase 1, dose-escalation trial demonstrate efficacy and safety of P-BCMA-101 CAR-T cell therapy in patients with R/R MM.

Postremission Survival Influenced by Choice of Induction Therapy in AML

Postremission Survival Influenced by Choice of Induction Therapy in AML

A single-center study demonstrated that induction therapy can influence OS and DFS in patients with intermediate or high NCCN risk acute myeloid leukemia.

Conception, Pregnancy Possible During TKI Therapy for Chronic Myeloid Leukemia

Conception, Pregnancy Possible During TKI Therapy for Chronic Myeloid Leukemia

A retrospective and prospective study of Italian adult patients with CML investigated the potential for childbearing and outcomes in this patient population.

Classical Massage Mitigates CIPN Due to Adjuvant Chemotherapy for Breast Cancer

Classical Massage Mitigates CIPN Due to Adjuvant Chemotherapy for Breast Cancer

Researchers sought to determine if the complementary practice could prevent CIPN in patients receiving adjuvant chemotherapy for breast cancer.

Quality of Life Decreased in Women With Breast Cancer During or Shortly After Pregnancy

Quality of Life Decreased in Women With Breast Cancer During or Shortly After Pregnancy

Study findings measure quality of life for pregnant patients with breast cancer and reveals the effectiveness of disease-specific assessment tools.

Systemic Imaging Not Effective in Detecting Metastatic Disease in Early-Stage Breast Cancer

Systemic Imaging Not Effective in Detecting Metastatic Disease in Early-Stage Breast Cancer

Study measures the usefulness of systemic imaging in early-stage breast cancer.

Postmastectomy Breast Reconstruction Safe in Older Women With Breast Cancer

Postmastectomy Breast Reconstruction Safe in Older Women With Breast Cancer

Few women aged 70 and older with breast cancer undergo postmastectomy breast reconstruction due to potential complications; however, these patients are not less likely to have good outcomes.

CIPN in Breast Cancer: Do Subjective and Objective Measures Correlate?

CIPN in Breast Cancer: Do Subjective and Objective Measures Correlate?

Researchers sought to determine how subjective measures of CIPN correlated with objective measures of CIPN.

Risk of Breast Cancer Higher for African American Female Veterans

Risk of Breast Cancer Higher for African American Female Veterans

Pilot study sought to determine risk of breast cancer among African American women veterans.

Patients, Physicians Do Not Recognize Fatigue the Same

Patients, Physicians Do Not Recognize Fatigue the Same

A worldwide survey reveals that despite similar perceptions on symptom burden of ITP, patients and physicians do not agree on the effect of fatigue on quality of life.

PFS, OS Improved With Sequential Rituximab/Bendamustine, Rituximab/Cytarabine in Untreated Mantle Cell Lymphoma

PFS, OS Improved With Sequential Rituximab/Bendamustine, Rituximab/Cytarabine in Untreated Mantle Cell Lymphoma

Two simultaneous studies demonstrate improved progression-free survival and overall survival in patients with uMCL who receive induction therapy with RB/RC followed by ASCT.

Recommended Therapies for Polycythemia Vera Underused

Recommended Therapies for Polycythemia Vera Underused

Phlebotomy and hydroxyurea tied to improved survival, lower risk for thrombosis in older patients.

Stringent Complete Response Criteria for Patients With Multiple Myeloma May Lack Predictive Value

Stringent Complete Response Criteria for Patients With Multiple Myeloma May Lack Predictive Value

Stringent CR criteria may not predict clinical outcomes for patients with multiple myeloma.

Rituximab Biosimilar CT-P10 Equivalent as Monotherapy for Follicular Lymphoma

Rituximab Biosimilar CT-P10 Equivalent as Monotherapy for Follicular Lymphoma

US FDA recently approved rituximab biosimilar as monotherapy and in combination with chemotherapy.

A Retrospective Look at Drug Sensitivity Before and After Checkpoint Blockade in R/R NHL

A Retrospective Look at Drug Sensitivity Before and After Checkpoint Blockade in R/R NHL

Checkpoint-based therapies may sensitize patients to subsequent therapies.

FDA Grants Approval to New Treatment for Acute Myeloid Leukemia

FDA Grants Approval to New Treatment for Acute Myeloid Leukemia

Randomized clinical trial showed significant improvement in overall survival with glasdegib.

Curative Option Identified for Squamous Cell Carcinoma of the Anal Canal With Distant Metastasis

Curative Option Identified for Squamous Cell Carcinoma of the Anal Canal With Distant Metastasis

A retrospective review identified a subset of patients with squamous cell carcinoma of the anal canal with distant metastases who respond to extended-field chemoradiation.

Perspectives on Use of Sensored Medication Devices From Patients With Multiple Myeloma

Perspectives on Use of Sensored Medication Devices From Patients With Multiple Myeloma

Researchers conducted a study to gauge the potential acceptance of sensored medication devices among patients with multiple myeloma.

Lung Cancer-Specific Distress Screening Tool Not Needed But Has Potential Benefit

Lung Cancer-Specific Distress Screening Tool Not Needed But Has Potential Benefit

Using focus groups, researchers evaluated patient-reported psychosocial consequences of lung cancer to determine if a lung cancer-specific distress screening instrument would benefit these patients.

Managing Rasburicase-Induced Hemolytic Anemia in G6PD-Deficient Population

Managing Rasburicase-Induced Hemolytic Anemia in G6PD-Deficient Population

Clinicians report on the challenges of managing rasburicase-induced G6PD deficiency in patients undergoing treatment for tumor lysis syndrome.

Addressing the Need for Palliative Care Training for Pediatric Oncologists

Addressing the Need for Palliative Care Training for Pediatric Oncologists

A review of studies on clinician education in palliative care identified themes for core palliative care competencies for pediatric oncologists.

Azacytidine, Nivolumab Combination Provides Safe, Effective Balance in Relapsed/Refractory AML

Azacytidine, Nivolumab Combination Provides Safe, Effective Balance in Relapsed/Refractory AML

Researchers investigated the safety and efficacy of combination therapy with azacytidine and nivolumab for relapsed/refractory AML.

Immunotherapy Side Effects May Be More Common Than Thought

Immunotherapy Side Effects May Be More Common Than Thought

Higher rates of adverse events observed for immune checkpoint inhibitors in real-world settings, compared to clinical trials.

Risk of Chemotherapy-Induced Neuropathy in Early Stage Breast Cancer Not Age-Related

Risk of Chemotherapy-Induced Neuropathy in Early Stage Breast Cancer Not Age-Related

Using data from the phase 3 trial CALGB 40101, researchers determined the risk for chemotherapy-induced neuropathy among patients with early-stage breast cancer receiving adjuvant paclitaxel weekly or biweekly.

Review Uncovers Common Reasons for Discontinuation of Oral Chemotherapy for Kidney Cancer

Review Uncovers Common Reasons for Discontinuation of Oral Chemotherapy for Kidney Cancer

A review is presented of adverse events common with 5 oral chemotherapy drugs used to treat renal cell carcinoma.

Obesity as a Teen Ups Risk for Later Pancreatic Cancer

Obesity as a Teen Ups Risk for Later Pancreatic Cancer

In men, overweight and even higher normal weight is associated with an increased risk of future pancreatic cancer.

Prophylaxis Improves Postchemotherapy Nausea/Vomiting Frequency, Hospitalizations

Prophylaxis Improves Postchemotherapy Nausea/Vomiting Frequency, Hospitalizations

Postchemotherapy hospitalizations and costs are higher for patients receiving highly emetogenic chemotherapy with no prophylaxis treatment.

Smartphone App Improves Management of Cancer-Related Pain, Anxiety

Smartphone App Improves Management of Cancer-Related Pain, Anxiety

Artificial intelligence and mobile technology combined in a smartphone app demonstrated an ability to accurately measure and respond to urgency of patients' pain.

Palliative Rehabilitation Improves Quality of Life in Newly Diagnosed Nonresectable Tumors

Palliative Rehabilitation Improves Quality of Life in Newly Diagnosed Nonresectable Tumors

Patients with nonresectable tumors randomized to palliative rehabilitation also chose to participate in individual consultations and a group program with physical activity.

Opioid Shortage Influences How Cancer-Related Pain Is Managed by Inpatient Palliative Care Team

Opioid Shortage Influences How Cancer-Related Pain Is Managed by Inpatient Palliative Care Team

Changes in pain management due to parenteral opioid shortage has initial negative effect, then stabilizes.

Tumor Lysis Syndrome, Renal Failure Complicate Elotuzumab Therapy for Multiple Myeloma

Tumor Lysis Syndrome, Renal Failure Complicate Elotuzumab Therapy for Multiple Myeloma

Proliferative state lead to rare case of TLS and renal failure in a patient with MM receiving elotuzumab.

Real-World Prevalence of AEs With Immune Checkpoint Inhibitors for NSCLC Higher Than Reported in Trials

Real-World Prevalence of AEs With Immune Checkpoint Inhibitors for NSCLC Higher Than Reported in Trials

Study suggests irAEs with PD-L1 therapy for NSCLC occur more frequently in real-world vs clinical trial populations.

Disparities Seen in Goals-of-Care Discussions With Minority vs Nonminority Patients

Disparities Seen in Goals-of-Care Discussions With Minority vs Nonminority Patients

Oncologists found to spend more time with nonminority patients discussing care goals than with minority patients.

Acupuncture Eases Some Self-Reported Symptoms of Cancer, Cancer Treatments

Acupuncture Eases Some Self-Reported Symptoms of Cancer, Cancer Treatments

Researchers presented results of a study on the effects of acupuncture treatments on pain, fatigue, nausea, and other effects of cancer and cancer treatment.

Risk for Colon Cancer, Osteogenic Sarcoma Higher With Presence of Diamond-Blackfan Anemia

Risk for Colon Cancer, Osteogenic Sarcoma Higher With Presence of Diamond-Blackfan Anemia

Researchers reviewed cancer incidence in patients with Diamond-Blackfan anemia.

G-CSF Support Increases Overall Survival, But Risk of Secondary Malignancies Also Higher

G-CSF Support Increases Overall Survival, But Risk of Secondary Malignancies Also Higher

A meta-analysis of 14 randomized, controlled trials was conducted to determine if combining G-CSF with intensified chemotherapy improved overall survival.

Report From Childhood Cancer Survivor Study Identifies Long-Term Risks for VTE

Report From Childhood Cancer Survivor Study Identifies Long-Term Risks for VTE

Assessment of long-term risks for VTE based on data from almost 30,000 childhood cancer survivors and siblings, with approximately 21 years of follow-up.

Outcomes Worse for Minimally Invasive Hysterectomy vs Open Surgery

Outcomes Worse for Minimally Invasive Hysterectomy vs Open Surgery

A comparison study of 2 approaches to radical hysterectomy found that disease-free and overall survival are worse with minimally invasive procedure than with abdominal open procedure, contradicting previous study findings.

Clinical Characteristics That Increase Risk of Chemotherapy-Induced Febrile Neutropenia Identified

Clinical Characteristics That Increase Risk of Chemotherapy-Induced Febrile Neutropenia Identified

Researchers analyzed data from more than 15,000 patients in Southern California with various cancers to identify clinical factors that contribute to the risk of developing chemotherapy-induced febrile neutropenia.

Dose-Escalation Mitigates Risk of Grade 3/4 Adverse Events With Ruxolitinib for Myelofibrosis

Dose-Escalation Mitigates Risk of Grade 3/4 Adverse Events With Ruxolitinib for Myelofibrosis

Results of an open-label phase 2 study demonstrated that a dose-escalation approach can prevent worsening anemia in patients with myelofibrosis undergoing treatment with ruxolitinib.

Patients and Caregivers Worry About Cost of Cancer Care

Patients and Caregivers Worry About Cost of Cancer Care

Survey also shows that Americans may be misinformed about alternative treatments for cancer.

Stem Cell Transplantation Superior to Chemotherapy for Relapsed/Refractory DLBCL, Follicular Lymphoma

Stem Cell Transplantation Superior to Chemotherapy for Relapsed/Refractory DLBCL, Follicular Lymphoma

A review of therapy options for relapsed/refractory DLBCL and FL compared SCT with chemotherapy/immunotherapy and experimental regimes. Patients fared better with SCT than other treatment modalities.

Head and Neck Cancer Survivors Have Increased Suicide Risk

Head and Neck Cancer Survivors Have Increased Suicide Risk

Survivors of head, neck cancers almost twice as likely to die from suicide as survivors of other cancers.

Hodgkin Lymphoma Survivorship Marked by Periods of Actionable Distress

Hodgkin Lymphoma Survivorship Marked by Periods of Actionable Distress

A retrospective evaluation of patients treated at a tertiary cancer center demonstrated that patients with Hodgkin lymphoma experienced periods of actionable distress in survivorship, despite a low overall distress burden.

Open Hysterectomy Survival Rates Edge Minimally Invasive Procedures for Cervical Cancer

Open Hysterectomy Survival Rates Edge Minimally Invasive Procedures for Cervical Cancer

A population-based study compared open abdominal radical hysterectomy with minimally invasive robot-assisted radical hysterectomy, and found a slight edge in survival among those who underwent the open procedure.

Study Reveals Relationship of Sleep Duration, Diabetes Risk in Cancer Survivors

Study Reveals Relationship of Sleep Duration, Diabetes Risk in Cancer Survivors

In a review of data from the National Health Interview Survey, researchers identified the relationship between short and long sleep durations and diabetes in cancer survivors.

Medication, Vaccination Uptake Improved by Involving Pharmacists in Elder Cancer Care

Medication, Vaccination Uptake Improved by Involving Pharmacists in Elder Cancer Care

Researchers explored the feasibility of integrating pharmacists into the oncology care team for older patients with cancer to determine the impact this intervention would have on medication management and vaccination uptake.

AAD Releases New Guidelines for the Treatment of Cutaneous Melanoma

AAD Releases New Guidelines for the Treatment of Cutaneous Melanoma

Guidelines recommend surgical excision as primary treatment modality, and emphasize individualized care.

Commission Seeks Standardized Adverse Event Assessments in Hematologic Malignancies

Commission Seeks Standardized Adverse Event Assessments in Hematologic Malignancies

A snapshot of an international Commission's report on the issues inherent with adverse event reports of hematologic malingnancies in clinical trials.

Molecular Features May Predict Response in Primary Pancreatic Cancer

Molecular Features May Predict Response in Primary Pancreatic Cancer 

The goal of this study was to determine how molecular features change when PDAC progresses from a primary tumor to metastatic disease.

Leukemia Risk in Children, Maternal Use of Hormonal Contraception Linked in Population Study

Leukemia Risk in Children, Maternal Use of Hormonal Contraception Linked in Population Study

A prospective cohort study from Denmark investigated the link between maternal hormonal contraception use before — more than 3 months and within 3 months — and during pregnancy and risk of leukemia in their children.

Delirium Can Hinder Effectiveness of Palliative Care in Advanced Cancer

Delirium Can Hinder Effectiveness of Palliative Care in Advanced Cancer

A prospective analysis of patients with advanced cancer revealed the effect delirium has on palliative care and symptom management at baseline and after 7 days of treatment.

Barriers to Prostate Cancer Research in Black Men Identified

Barriers to Prostate Cancer Research in Black Men Identified

Mistrust, lack of knowledge, unfavorable attitudes are barriers to genomic testing, study participation

New Method Estimates Risk for Breast Cancer Recurrence

New Method Estimates Risk for Breast Cancer Recurrence

Higher recurrence risk linked to older age, more advanced stage, HR-negative tumors.

CheckMate 067 Gives Nivolumab Alone, With Ipilimumab the Nod in Advanced Melanoma

CheckMate 067 Gives Nivolumab Alone, With Ipilimumab the Nod in Advanced Melanoma

Survival and progression-free survival were better with nivolumab alone or with ipilimumab vs ipilimumab alone for stage III or IV melanoma with known BRAFV600 mutation, according to results of this randomized study.

PACC Guidelines Recommend IT Morphine, Ziconotide for Chronic Pain

PACC Guidelines Recommend IT Morphine, Ziconotide for Chronic Pain 

The 2016 evidence-based PACC guidelines recommend the use of morphine and ziconotide as effective and safe first-line IT monotherapies for chronic pain.

ASCO, SITC Release Recommendations for Clinical Trial Reporting of Immunotherapy Adverse Events

ASCO, SITC Release Recommendations for Clinical Trial Reporting of Immunotherapy Adverse Events

As immunotherapies gain a stronger foothold as a treatment option for cancer, ASCO and SITC convened a panel to develop recommendations to ensure consistent and efficient clinical trial reporting in immuno-oncology.

Dietary Habits May Prolong Survival in Patients With Colorectal Cancer

Dietary Habits May Prolong Survival in Patients With Colorectal Cancer

A prospective analysis of diets before and after diagnosis revealed dietary habits among patients with colorectal cancer that may help prolong survival.

Risk Factors for Higher-Grade Transformation in Marginal Zone Lymphomas Identified

Risk Factors for Higher-Grade Transformation in Marginal Zone Lymphomas Identified

In a retrospective evaluation, investigators sought to identify risk factors for higher-grade transformation in patients with marginal zone lymphomas.

Standardization Could Improve Tumor Board Interpretation, Recommendations

Standardization Could Improve Tumor Board Interpretation, Recommendations

Using fictional patient profiles and a questionnaire on recommendation procedures, researchers were able to demonstrate a need for standardized tumor board interpretation and recommendation processes worldwide.

Postoperative Radiotherapy Favorable as Adjuvant Treatment for Thymic Neuroendocrine Tumors

Postoperative Radiotherapy Favorable as Adjuvant Treatment for Thymic Neuroendocrine Tumors

A propensity-score matched analysis was used to determine the effect of surgery and postoperative radiotherapy in patients with TNETs.

Prior Bortezomib Lowers Incidence of Lenalidomide-Induced Skin Toxicity in Multiple Myeloma

Prior Bortezomib Lowers Incidence of Lenalidomide-Induced Skin Toxicity in Multiple Myeloma

A study presented at ESMO 2018 demonstrated that incidence of skin toxicity in patients with multiple myeloma undergoing lenalidomide therapy was lower in those who received prior bortezomib.

Conference Placeholder Article

Conference Placeholder Article

This is only a test.

How Likely Are Oncologists to Refer for Palliative Care? Depends on Their Age

How Likely Are Oncologists to Refer for Palliative Care? Depends on Their Age

Study shows that referrals to palliative care and time to referral are relative to the age of the treating oncologist, with higher numbers and quicker referrals among younger oncologists.

Nonadherence to Tamoxifen Higher Than Reported Among Premenopausal Patients With Breast Cancer

Nonadherence to Tamoxifen Higher Than Reported Among Premenopausal Patients With Breast Cancer

Assessment of a subgroup of a cohort study revealed that many patients undergoing tamoxifen therapy for early-stage breast cancer do not adhere to their prescribed treatment, even though they claim adherence on patient surveys.

Chemoimmunotherapy Increases Survival in Triple-Negative Breast Cancer

Chemoimmunotherapy Increases Survival in Triple-Negative Breast Cancer

Atezolizumab plus nab-paclitaxel prolongs progression-free survival in metastatic disease.

Chemotherapy Side Effects in Women vs Men: Broader Range, More Severe

Chemotherapy Side Effects in Women vs Men: Broader Range, More Severe

An analysis of pooled data from 4 randomized controlled clinical trials revealed that male and female patients experience different chemotherapy side effects and at different severities, according to a poster presented at ESMO 2018 Congress.

Many Breast Cancer Survivors' Desire for Pregnancy Changes After Treatment

Many Breast Cancer Survivors' Desire for Pregnancy Changes After Treatment

Researchers surveyed 60 breast cancer survivors to determine if their desire to achieve pregnancy had changed after completing treatment. These findings were presented at ESMO 2018 Congress.

Shorter Trastuzumab Course Achieves Similar DFS, Less Cardiac Toxicity in HER2+ Breast Cancer

Shorter Trastuzumab Course Achieves Similar DFS, Less Cardiac Toxicity in HER2+ Breast Cancer

Study findings presented at ESMO 2018 Congress revealed the effect of a shorter, 9-week course of trastuzumab on disease-free survival (DFS) and cardiac toxicity in women with HER2-positive breast cancer.

Light Use of Topical Skin Treatments Before Radiotherapy Appears Safe

Light Use of Topical Skin Treatments Before Radiotherapy Appears Safe

Radiation dose not impacted with light or moderate use of skin treatments, regardless of beam energy, incidence.

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