High VEGF Signaling Score Tied to Lung Cancer Prognosis
High score correlates with good prognosis in patients with early lung squamous cell carcinoma.
Diagnosis & Disease Information
Assay can predict survival
A new molecular test is more accurate at predicting high risk for death after surgical resection of early-stage nonsquamous NSCLC.
Melanoma treatment creates risk of secondary skin cancer
Investigators have discovered why the pill Zelboraf (vemurafenib), effective against melanoma, may also cause the development of a secondary skin cancer: squamous cell carcinoma.
Connected nodes in throat cancer signal poor prognosis
The presence of “matted” lymph nodes (nodes connected together) in persons with oropharyngeal squamous cell carcinoma was associated with 3-year survival of 69% rather than 94%.
Fibrous stroma heralds poor prognosis for some lung tumors
People with the squamous cell carcinoma subtype of non-small cell lung cancer have significantly worse outcomes if these tumors are surrounded by fibrous stroma as opposed to thin stroma.
Protein interaction creates a new treatment target for squamous cell carcinoma
A tumor-suppressing protein called alpha-catenin appears to stop the development of squamous cell carcinoma by keeping another protein—the cancer-causing Yap1—in check.
The diagnosis of vulval intraepithelial neoplasia
Vulval intraepithelial neoplasia (VIN) is a premalignant lesion involving the squamous epithelium of the fulva. It is relatively uncommon but has a chronic course and is often difficult to eradicate. The risk of VIN developing into an invasive carcinoma means that is should be managed by clinicians with appropriate expertise
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