With only 1 slide of a tumor section, an analysis of multiple tumor markers can be performed. The technique may help predict response to immunotherapy, which typically evokes responses in only a small group of patients.
Resistance to therapy through adaptation poses a major hurdle for cancer therapy. Bioengineers addressed this by creating a single nanoparticle that comprises a synergistic drug pair that shuts down mechanisms of resistance to a degree that has not been previously achieved.
A single dose and a beam of light can kill up to 95% of cancer cells in 2 hours, according to preclinical research on a novel approach to tumor resection. Photodynamic cancer therapy may be a treatment option for people whose tumors are inoperable or hard-to-reach.
A widely prescribed pain/anti-inflammatory medication reduced the growth of neurofibromatosis type 2 tumors in mice and in cell cultures, suggesting that the drug could reduce tumor growth in some cancers.
Tumors of varied types of genetically defined cancer were significantly reduced by the drug LOXO-101, according to phase 1 study results.
Gene therapy with a T cell receptor targeting a single cancer-specific point mutation is being used to eradicate large solid tumors.
Lower patient survival and worse clinical outcomes across a variety of cancer types were correlated with increased expression of 4 genes in the Ly6 gene family. These findings came from an analysis of 130 gene expression studies from 10 solid cancers.
Analyzing tumor DNA fragments in the bloodstream, known as circulating tumor DNA (ctDNA), may offer a more complete view of a patient’s cancer from a molecular perspective.
Optical probes that make cancer cells glow and improve surgical tumor removal are in phase I and II clinical trials in humans. The probes could be commonplace in the next 5 to 10 years, hypothesize the researchers.
A new injectable agent causes cancer cells in a tumor to fluoresce, potentially enabling surgeons to locate and remove all of a cancerous tumor on the first attempt.
