Arthritis drugs may raise risk of skin cancer
Tumor necrosis factor (TNF) inhibitors—biologic agents used in the treatment of rheumatoid arthritis—appear to increase the risk of skin cancer, including melanoma.
Diagnosis & Disease Information
Frailty undermines outcomes in melanoma
In persons with stage III melanoma, frailty—not age—was associated with decreased disease-free survival and distant disease-free survival, and with more surgical complications.
Caffeine: The new sunblock?
Applying caffeine directly to the skin may eventually prove to help prevent sunlight-induced skin cancer, suggest the findings from a recent mouse study.
New FDA regulations for sunscreens
The Food and Drug Administration issued new regulations for sunscreen testing and labeling to help consumers choose products that offer the best protection.
Shave biopsy okay for initial staging of malignant melanoma
Shave biopsies may potentially hamper accurate diagnosis and staging of melanoma, but a study indicates that they are reasonably safe and accurate for the initial evaluation of the disease.
Protein interaction creates a new treatment target for squamous cell carcinoma
A tumor-suppressing protein called alpha-catenin appears to stop the development of squamous cell carcinoma by keeping another protein—the cancer-causing Yap1—in check.
Autoimmune vitiligo may help fight melanoma
Inducing vitiligo in persons with melanoma might enhance the natural immune response of these patients, according to data yielded by a recent study.
Blood biomarkers may foretell melanoma metastasis risk
The identification of several plasma biomarkers that appear to predict the risk of metastasis in melanoma could lead to more convenient and less costly monitoring of persons with this cancer.
Overall cancer mortality rates decrease, but incidence of some cancers increases
Overall, cancer incidence rates fell approximately 1% annually and overall death rates decreased by an average of 1.6% annually between 2003 and 2007.
COX-2 inhibitor may protect against some skin cancers
Celecoxib (Celebrex) may ward off squamous and basal cell carcinomas in persons with extensive actinic damage who are at high risk for developing nonmelanoma skin cancers.
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