Gene sequencing can match patients to best cancer trials
Identifying the “mutational landscape” of a person’s cancer is a promising method of determining which trials are best-suited to the patient’s particular case.
Diagnosis & Disease Information
Laser therapy may be an option in removal of premalignant skin lesions
When surgery or radiation therapy cannot be used to remove the common precancerous skin lesion lentigo maligna, carbon dioxide laser ablation may be a useful alternative.
New treatments are improving outcomes in melanoma
Targeted therapy, combination therapies, vaccines, and new treatment modalities demonstrate promising prognoses for these patients.
Arthritis drugs may raise risk of skin cancer
Tumor necrosis factor (TNF) inhibitors—biologic agents used in the treatment of rheumatoid arthritis—appear to increase the risk of skin cancer, including melanoma.
Frailty undermines outcomes in melanoma
In persons with stage III melanoma, frailty—not age—was associated with decreased disease-free survival and distant disease-free survival, and with more surgical complications.
Caffeine: The new sunblock?
Applying caffeine directly to the skin may eventually prove to help prevent sunlight-induced skin cancer, suggest the findings from a recent mouse study.
New FDA regulations for sunscreens
The Food and Drug Administration issued new regulations for sunscreen testing and labeling to help consumers choose products that offer the best protection.
Shave biopsy okay for initial staging of malignant melanoma
Shave biopsies may potentially hamper accurate diagnosis and staging of melanoma, but a study indicates that they are reasonably safe and accurate for the initial evaluation of the disease.
Protein interaction creates a new treatment target for squamous cell carcinoma
A tumor-suppressing protein called alpha-catenin appears to stop the development of squamous cell carcinoma by keeping another protein—the cancer-causing Yap1—in check.
Autoimmune vitiligo may help fight melanoma
Inducing vitiligo in persons with melanoma might enhance the natural immune response of these patients, according to data yielded by a recent study.
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