CMB305 Vaccine Demonstrates Activity But Doesn’t Improve Survival in Soft-Tissue Sarcomas
CMB305 increased antibody responses and NY-ESO-1-specific T-cell responses.
Diagnosis & Disease Information
Nanoparticle Albumin-Bound mTOR Inhibitor Gets Priority Review for Ultra-Rare Sarcoma
Nab-sirolimus is an mTOR inhibitor bound to human albumin.
ETS Inhibitor and Vincristine Exhibit Antitumor Activity in Relapsed/Refractory Ewing Sarcoma
The combination produced 2 complete responses.
American Cancer Society 2021 Statistics Report Shows Continuous Decline in Cancer Mortality Rate, Illuminates Disease-Specific Trends
The American Cancer Society’s annual report approximates the new cancer diagnoses and deaths expected in 2021 and identifies impactful patterns in oncology care.
Expanding HDR Brachytherapy Program at a Rural Cancer Center to Include Soft Tissue Sarcoma
A facility in northwest Montana shares its experiences with developing a brachytherapy service and expanding it to include treatment of soft tissue sarcoma.
Radiomic, Clinical Features Predicted Sarcoma Response to Radiation
Radioresistant sarcoma may require treatment intensification.
Radiation for Abdominal, Pelvic Cancers Ups Secondary Sarcoma Risk
Compared with patients who undergo surgery alone for abdominal or pelvic cancers, those who receive radiation and chemotherapy are at elevated risk for secondary sarcomas.
Few High-Grade Soft Tissue Sarcoma Patients Receive Chemo
Percentage of STS patients receiving chemo driven by factors such as tumor size, income, facility type.
Addition of Pazopanib to Neoadjuvant Chemo Found Highly Active in Adult, Pediatric Sarcoma
The study is a collaboration of pediatric, adult cooperative groups.
Management of Refractory Pediatric Sarcoma: Current Challenges and Future Prospects
[OncoTargets and Therapy] While multimodal treatment can be curative in select cases of r/r pediatric sarcoma, treatment refractoriness remains a tremendous hurdle for clinicians.
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