Lorlatinib Under Review for Previously Untreated ALK-Positive NSCLC
The sNDA is supported by data from the phase 3 CROWN study comparing lorlatinib to Xalkori in 296 adults with advanced ALK-positive NSCLC.
The sNDA is supported by data from the phase 3 CROWN study comparing lorlatinib to Xalkori in 296 adults with advanced ALK-positive NSCLC.
The approval was based on a pre-specified interim analysis from the open-label phase 3 CheckMate -743 trial.
The trial, which is the first to be implemented under Operation Warp Speed, is expected to enroll around 30,000 adults and will be conducted at multiple clinical research sites across the US.
The use of telemedicine has been surging since the onset of coronavirus disease 2019 (COVID-19), with millions of Americans now using this medium for connecting with their clinicians, according to a report that appeared in Kaiser Health News.1 The increase in use of this modality can be attributed to fears of contracting COVID-19, social distancing…
Healthcare professionals are being advised to monitor patients regularly for pulmonary symptoms indicative of ILD and/or pneumonitis, including hypoxia, cough, dyspnea, and interstitial infiltrates on radiologic exams.
The emissions from electronic-cigarettes have distinct properties from those produced by combustion processes and may cause or worsen acute respiratory diseases, according to a report.
Cancer patients often experience respiratory complications, whether related to the malignancy or treatment with radiation to the chest area or chemotherapy.