DNA overexpression may signal cancer
Certain DNA sequences were never suspected of having a role in cancer—until now. Cells in the most common type of solid tumor have now been found to feature massive overexpression of these sequences.
Diagnosis & Disease Information
Tuberculosis makes lung cancer almost 11 times more common
People with pulmonary tuberculosis appear to be at heightened risk of developing lung cancer, according to the results of a large, long-term study.
Iniparib impressive in triple-negative breast cancer
Adding iniparib to gemcitabine and carboplatin significantly increased clinical benefit and survival—but not toxic effects—in women with metastatic triple-negative breast cancer.
PML presence could be benign sign
The easy-to-detect tumor suppressor PML may help distinguish benign tumors from cancers, now that researchers have found benign cells produce the PML molecule and display abundant PML bodies.
Body’s protein can stall tumor spread
A naturally occurring protein inhibits tumor growth and metastasis into secondary organs and has the potential to be developed into an anticancer drug, scientists have found.
NCI to overhaul clinical trials system
A major transformation is under way for the National Cancer Institute’s Clinical Trials Cooperative Group Program, which conducts many of the nationwide trials for new cancer therapies.
Gene deletion may explain many cases of glioblastoma
An important gene deletion appears to occur in as many as 1 of every 4 cases of glioblastoma—the most common adult brain cancer—scientists have found.
Cancer biomarkers fail to show promise for use in clinical settings
The failure of discoveries involving cancer biomarkers to fuel clinical success may stem from many problems, according to a study published in the Journal of the National Cancer Institute (2010 Aug 12. [Epub ahead of print]).
Therapeutic properties of arsenic may help treat cancer
Doctors may be able to treat cancer effectively by combining arsenic with other therapies, according to a study published in the Proceedings of the National Academy of Sciences (2010 Jul 12. [Epub ahead of print]).
The methods and terminology of cancer trials: A review
Oncology nurses involved in clinical trials must understand the basics of cancer research and their practice’s studies.
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