[Breast Cancer: Targets and Therapy] This review focuses on alpelisib, a PI3K inhibitor, approved for the treatment of HR+/HER2 negative metastatic breast cancer in patients with a PIK3CA mutation who have received prior endocrine therapy.
[OncoTargets and Therapy] Investigators from the Mayo Clinic in Jacksonville, Florida, review treatment strategies for mCRPC using CDK4/6 inhibitors and combination therapies.
[Cancer Management and Research] This study was to establish models that respectively predict malignancy risk of incidental solid and subsolid pulmonary nodules of different size.
[Cancer Management and Research] A retrospective review of 30 patients who underwent resection of spinal tumor caused by metastatic SCLC demonstrated that surgery was critical to improving patients QOL and performance status.
[Cancer Management and Research] Researchers sought to determine if apatinib-related hypertension was a predictor of drug efficacy in patients with advanced HCC.
[Oncotargets and Therapy] Some data support use of immunotherapy for breast cancer; however, as a monotherapy, only a small percentage of patients will benefit from the treatment. This review discusses the current status of efforts to improve immunotherapy through combinations with other therapies.
[Cancer Management and Research] This review focuses on how identification of molecular alterations and risk stratification would contribute to individualized-therapeutic decision-making in AML.
[Journal of Hepatocellular Carcinoma] In this review, the authors discuss the use of imaging techniques and radiological biomarkers to monitor treatment response in patients with advanced HCC undergoing antiangiogenic therapy, a key to decisions on whether to continue treatment or initiate second-line therapy.
[Breast Cancer: Targets and Therapy] A review of the data on this newer peptide vaccine being explored as potential vaccine therapy for HER2-positive and triple negative breast cancers.
[Cancer Management and Research] In this study, researchers investigated whether preoperative prognostic nutritional index, prealbumin, and the albumin to globulin ratio were predictive of survival outcomes for patients with colon and rectal cancers.
