Adjuvant Nivolumab + Ipilimumab Lacks Efficacy for Localized RCC
Trial did not meet primary efficacy end point of disease-free survival in patients with localized RCC at high risk for postnephrectomy relapse.
Renal Cell Carcinoma
COSMIC-313: Triplet Prolongs PFS vs Doublet in Renal Cell Carcinoma
The PFS benefit was driven primarily by patients with intermediate-risk disease.
Immune Checkpoint Inhibitor Therapy Linked With Improved Quality of Life
Among patients with a variety of solid tumors, investigators found favorable associations of immune checkpoint inhibitor therapy with quality of life compared with no immunotherapy use.
Normonatremia Tied to Outcomes in Metastatic Renal Cell Carcinoma
Serum sodium levels in the lower end of the normal range are associated with inferior outcomes in metastatic renal cell carcinoma, a study suggests.
Estimating Post-Nephrectomy GFR May Guide Treatment Decisions
An accurate estimate of future GFR after nephrectomy would help to guide operative strategy and use of adjuvant or neoadjuvant therapies, according to a recent editorial.
Previous Cannabis Use Linked to Lower Risk of Some Genitourinary Cancers
A new study suggests that previous use of cannabis is associated with a lower risk of certain genitourinary cancers.
Reduced Initial TKI Dose Comparable to Full Dose in Metastatic Renal Cell Carcinoma
Researchers sought to determine if reducing the starting dose of TKI therapy in patients with metastatic RCC would improve tolerability without reducing efficacy.
Medically Integrated Dispensing on the Rise in US Oncology Practices
From 2010 to 2019, the percentage of oncology practices with medically integrated dispensing more than doubled.
Kidney Failure Risk Higher After Kidney Cancer Surgery
Investigators report a cumulative 10-year incidence of end-stage kidney disease of 2.5% among patients who undergo surgery for renal cell carcinoma (RCC), which is 10 times higher than in patients without RCC.
Obesity Is Associated With Increased Risk for Renal Cell Carcinoma
New findings challenge the notion of an obesity paradox with regard to cancer-related survival.
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