[Breast Cancer: Targets and Therapy] This study compared the technique, process, and outcomes of external beam radiation therapy with those of 3-dimensional conformal radiation therapy, finding that benefits of the APBI technique included fewer side effects and reduced treatment periods.
[Journal of Hepatocellular Carcinoma] In this study, investigators sought to determine how socioeconomic differences influenced outcomes for patients in Florida with HCC. They found that despite having lower socioeconomic status, Hispanic patients with HCC fared better than both black and white patients with HCC.
[OncoTargets and Therapy] In this review, researchers describe the pathophysiology of myeloma bone disease and discuss the significance of preventing skeletal-related events in patients with MM.
[OncoTargets and Therapy] The aim of this study was to evaluate the impact of SNM on nutritional status, treatment-related toxicity, QoL, response rates, and survival in LA-NPC patients treated by RT.
[Cancer Management and Research] In this review, the authors explore barriers to greater use of radiotherapy related to wrong perceptions and lack of knowledge in both physicians and patients that may be contributing to a lack of referrals to radiation oncology.
[OncoTargets and Therapy] This review of proton therapy discusses its physical basis, rationale for its use in patients with lymphoma, and the potential disadvantages and uncertainties that may limit its use; and offers a critical review of the dosimetric studies comparing the risk of latent radiation injuries between proton and photon radiotherapy.
[Breast Cancer: Targets and Therapy] This review discusses the current evidence and future perspectives regarding use of cryoablation, a minimally invasive technique, in the treatment of early breast cancer.
[OncoTargets and Therapy] This review discusses the use of targeted therapies to treat pheochromocytoma and paraganglioma, rare tumors that are created from adrenal or extra-adrenal chromaffin cells. Although usually initially benign and nonmetastatic, these tumors can cause serious organ damage and even death.
[Cancer Management and Research] Researchers sought an alternative regimen for urine alkalization in patients receiving high-dose methotrexate. The typical regimen, IV sodium bicarbonate, has been on shortage. This study determined the safety of an oral regimen of sodium bicarbonate and acetazolamide to achieve a urine pH >7, which is necessary for safe administration of high-dose methotrexate.
[Cancer Management and Research] In a meta-analysis of 12 clinical studies, researchers sought to determine if patients with HER2-overexpression breast cancer experienced better OS with neoadjuvant or adjuvant trastuzumab, and to assess LRR rate in women with this tumor and treatment after mastectomy and after BCT.
