Molecularly Matched Therapy Promising in Pancreatic Cancer
Overall survival significantly longer for patients with actionable molecular alterations receiving matched therapy.
Pancreatic Cancer
Multiple Factors Associated With Hospital Readmission Following Pancreatectomy for Cancer
Results of this study showed no improvement in the rate of 30-day hospital readmission for patients with cancer undergoing pancreatectomy between 2005 and 2011.
Addition of Pegilodecakin to FOLFOX Did Not Improve OS in Metastatic Pancreatic Cancer
Promising results from an earlier-phase study of FOLFOX plus pegilodecakin in metastatic PDAC refractory to gemcitabine provided a rationale for this study.
Addition of PEGPH20 to Frontline Chemotherapy Did Not Improve Clinical Outcomes in Pancreatic Cancer Subgroup
Pegvorhyaluronidase alfa is an enzyme that breaks down hyaluronan, thought to be a contributor to the structure of the tumor microenvironment in some pancreatic cancers.
No Link Found Between Hepatitis C Infection and Extrahepatic Cancers
A study of an Asian population failed to find a link between the virus and malignancies outside of the liver.
Lynparza Gains Pancreatic Cancer Indication
The US FDA has approved olaparib for the maintenance treatment of some adult patients with deleterious or suspected deleterious germline BRCA-mutated (gBRCAm) metastatic pancreatic adenocarcinoma.
Gene Fusions Found in Pancreatic, Biliary IOPNs
Patterns of genetic alterations could guide management.
Risk for Cancer Incidence, Mortality Increased With Psoriasis
Overall cancer mortality and mortality for liver, esophageal, pancreatic cancer up with severe psoriasis.
Some Targeted Therapies May Miss the Mark
Ten different drugs continued to kill cancer cells even when their target proteins were removed.
ASTRO Issues Guideline for Radiation Treatment in Pancreatic Cancer
Evidence reviewed for radiation therapy in adjuvant, neoadjuvant, definitive, and palliative settings.
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