Simple Adjustment Key to Paclitaxel Infusion Protocol That Reduced Hypersensitivity Reactions
A project presented at the 2018 ONS Annual Congress demonstrated the effectiveness of standardizing nursing practices for paclitaxel infusions.
Diagnosis & Disease Information
Cryotherapy May Help Prevent Chemo-Induced Neuropathy
Breast cancer patients on paclitaxel had lower incidence of peripheral neuropathy with cryotherapy, researchers found.
Research Identifies Underlying Mechanism of Chemotherapy-Induced Peripheral Neuropathy
A previously unidentified avenue exists for potential therapies for peripheral neuropathy induced by the chemotherapeutic agent paclitaxel.
Weekly Paclitaxel Doesn’t Increase Survival in Ovarian Cancer
Paclitaxel administered with carboplatin on a weekly basis is not associated with improved progression-free survival.
Concurrent Chemoradiotherapy Using Paclitaxel Plus Cisplatin in the Treatment of Elderly Patients With Esophageal Cancer
The purpose of this research was to examine both efficiency and safety of concurrent chemoradiotherapy (CCRT) using paclitaxel combined with cisplatin in elderly esophageal cancer patients.
Artificial Intelligence May Better Predict Response in Breast Cancer Treatment
Researchers are working on a way to use artificial intelligence to predict a patient’s response to two common chemotherapy drugs used to treat breast cancer: paclitaxel and gemcitabine.
Molecular tinkering doubles cancer drug’s efficacy
By surrounding molecules of paclitaxel with self-assembling spheres composed of amino acids, researchers doubled tumor exposure to the drug and reduced its effects on healthy tissue.
Fostamatinib-paclitaxel combination may shrink ovarian cancers
Researchers have found that the experimental drug fostamatinib, combined with the chemotherapy drug paclitaxel, may overcome ovarian cancer cells’ resistance to paclitaxel.
Rare gene variants associated with side effects from paclitaxel
Researchers have identified the first genetic marker associated with severe neurologic toxicity from paclitaxel.
Nab-paclitaxel demonstrated superior activity vs paclitaxel in early breast cancer
Nab-paclitaxel has demonstrated significant benefit for patients with early high-risk breast cancer when compared with conventional solvent-based paclitaxel, according to recent research.
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