Classifying Oropharyngeal Cancer by p16 Status Alone Deemed Insufficient
Oropharyngeal cancer patients who have discordant p16 and HPV status have worse prognosis than patients who have p16+/HPV+ disease, a study suggests.
Diagnosis & Disease Information
Increased Uptake of HPV Vaccine Projected to Reduce Oropharyngeal Cancer Incidence Over 25 Years
A new study projects that increasing HPV vaccination rates will trend toward reduced incidence of oropharyngeal cancer among younger adults until 2045.
Factors Identified for Poor Long-Term Survival in RT-Treated Patients With Oropharyngeal Cancer
This analysis identified the factors for poor long-term survival in radiotherapy (RT)-treated patients with oropharyngeal cancer (OPC).
Transoral Robotic Surgery Ups Survival in Oropharyngeal Cancer
Outcomes and survival improved for early-stage oropharyngeal cancer, but not other cancers.
Weight and Swallowing-Related Quality of Life in Patients Treated for Oropharyngeal Cancer
Single-center study reports on the effects of oropharyngeal cancer treatment at 3, 6, and 12 months after chemoradiotherapy or radiotherapy alone, and with and without a feeding tube.
Mortality Risk in Oropharynx Cancer Varies Based on HPV Status
Patients with OPC with HPV-negative tumors have increased risk for head and neck cancer mortality.
Incidence of HPV-Positive Head and Neck Cancer Up in the U.S.
From 2013 to 2014, incidence of HPV-positive oropharyngeal cancers was 4.62 per 100,000 persons.
Toxicity Similar, But Overall Survival Poor in Cetuximab vs Cisplatin for HPV-Positive Oropharyngeal Cancer
In a randomized phase 3 trial, researchers sought to determine if cetuximab-based chemoradiotherapy could be a less-toxic alternative to cisplatin-based chemoradiotherapy in patients with HPV-positive oropharyngeal cancer.
Late Lower Cranial Neuropathy Worsens Symptom Burden in Oropharyngeal Cancer Survivors
Researchers conducted a cross-sectional study to determine the incidence and effect of late lower cranial neuropathies on survivors of oropharyngeal cancers.
Incidence, Age at Diagnosis Increasing in HPV-Positive Oropharyngeal Squamous Cell Carcinoma
A retrospective study demonstrates an increase in HPV16-positive status among patients with OPSCC and a corresponding increase in age at diagnosis.
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