Update on Therapeutic Options for Myelofibrosis
A review of myelofibrosis, including an update on treatment options, was presented at the 2023 ONA Summit.
Diagnosis & Disease Information
Momelotinib Found Superior to Danazol for the Treatment of Myelofibrosis
Researchers sought to determine if momelotinib provided better improvements in anemia in patients with myelofibrosis, compared with treatment with danazol.
Associations of Mutations in Spliceosome Genes With Ring Sideroblasts Verified in Myelodysplastic Syndromes
Researchers sought to verify the association of mutations in the splicing pathway gene SF3B1 with low bone marrow blast counts and increased ring sideroblasts in MDS.
Monoclonal Antibody Shows Promise for Treating MPNs in Preclinical Study
Preclinical research suggests that a monoclonal antibody may be effective for treating CALR-mutant myeloproliferative neoplasms.
Coexisting Myeloproliferative Neoplasms and Atrial Fibrillation Increases Risk of CV Events
Researchers investigated the risk of cardiovascular events in patients with MPN and atrial fibrillation, and evaluated the predictive value of traditional risk scores.
Best Practices for Effective MPN Case Management in the Outpatient Setting
The symptoms and care needs of patients with myeloproliferative neoplasms are discussed in a report on effective care management for these patients.
Endoscopic Procedures Improve Gastroesophageal Variceal Rebleeding in MPN
Researchers sought to determine the efficacy of endoscopic management of recurrent GVB in patients with MPN.
Besremi Approved for Adults With Polycythemia Vera
Besremi is a monopegylated, long-acting interferon, which exhibits its cellular effects in the bone marrow in polycythemia vera.
Study Advances Knowledge Base About Children and Adolescents With Myeloproliferative Neoplasms
The researchers uncovered higher-than-anticipated rates of thrombosis, hemorrhage, and transformation in their real-world cohort of MPN patients.
Mobile Exercise App Feasible During Outpatient Chemotherapy for Myeloid Neoplasms
Pilot trial sought to determine the efficacy of using GO-EXCAP, a mobile application, to improve exercise frequency and duration in older patients receiving chemotherapy for myeloid neoplasms.
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