AI Model May Predict Immunotherapy Response in Melanoma
Histology slides, clinical data used to predict immune checkpoint inhibitor response in advanced melanoma.
Melanoma
Effects of Drugs Targeting Mitochondrial Respiration in Melanoma
Despite relying on glycolysis, there is growing evidence that many tumor types still have high levels of mitochondrial energy metabolism and functioning oxidative phosphorylation. One such subset of tumors is melanoma, potentially playing a role in both tumor progression and resistance to therapy. This has led researchers to wonder whether targeting mitochondrial respiration could be…
Research Shows Long-Term Benefit for Adjuvant Targeted Therapies in High-Risk Melanoma
More than half of patients with resected stage 3 melanoma with BRAF V600E or V600K mutations receiving a year’s worth of adjuvant dabrafenib and trametinib were still alive 5 years later.
Risk of Melanoma Measured in Mutation Burden of Skin Cells
Mutation count could offer personal screening guidelines.
How Do Melanoma Comorbidities Affect Patient Treatment Preferences?
Comorbidities can have an impact on what you as a medical professional think is the best course of treatment for your patients. Can they also affect a patient’s thinking on treatment? Comorbidities such as cardiovascular disease, hypertension, and depression can contribute to how a patient’s body responds to treatment and its attendant stress. A recent…
Racial Disparities in Melanoma-Specific Survival Persist
If, and to what degree, racial disparity in melanoma-specific survival (MSS) has persisted since 2010 was evaluated.
Melanoma Treatment Regimens
View treatment regimens for melanoma, including guidance on options and dosing for a number of drugs including ipilimumab and dacarbazine.
Immunotherapy Plus Radiotherapy After Surgery Improves OS in Tumors With Brain Metastases, Study Finds
Study found adding immunotherapy to radiotherapy significantly improved OS after definitive surgery for primary tumor in patients with brain metastasis.
Immunotherapy for the Treatment of Melanoma and Lung Cancer
Immunotherapy has improved outcomes for patients with cancer, despite several drawbacks. This review provides an overview of how to manage patients undergoing therapy with these drugs.
Tecentriq Plus Cotellic and Zelboraf Approved for Advanced Melanoma
The approval was based on data from the multicenter, double-blind, placebo-controlled phase 3 IMspire150 study.
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