Periadjuvant Pembrolizumab Improves EFS in Resectable Melanoma
Periadjuvant pembrolizumab may improve outcomes over adjuvant pembrolizumab alone in patients with resectable stage III-IV melanoma, a phase 2 study suggests.
Diagnosis & Disease Information
PASS: A Novel Dermoscopic Algorithm for Diagnosing Cutaneous Melanomas
Investigators in Spain developed an algorithm for diagnosing melanomas that had good diagnostic accuracy and was easier to perform than other diagnostic algorithms.
AYA Patients With Melanoma Fare Worse at All Stages Than Older Adults
Researchers compared all-cause and melanoma-specific mortality in patients aged 15 to 39 years and 40 to 64 years with advanced melanoma.
Regular Use of Vitamin D Linked to Fewer Melanoma Cases
Lower percentage of individuals seen with history of past or present melanoma, any type of skin cancer among regular users.
Survival Rates High for Children, Teens With Melanoma
Primary tumor ulceration, head/neck location, and Breslow thickness >4 mm predict worse survival in teens.
Moderna, Merck Report on Promising Melanoma Vaccine
Companies announced that the vaccine performed well in a small study of patients who had the cancer surgically removed.
Presence of Many Nevi Increases Risk for Second Primary Melanoma Diagnosis
A study in Australia explored the factors that increase the risk for a second primary melanoma.
Tumor-Infiltrating Lymphocytes Up PFS in Advanced Melanoma
Significantly longer progression-free survival seen with infusion of tumor-infiltrating lymphocytes versus ipilimumab.
Melanoma Diagnosis Linked to Increased Risk of Prostate Cancer
More than twofold increased risk of prostate cancer seen for men with first melanoma diagnosed 10 to 15 years before study recruitment.
Subset of Stage I Melanoma Patients ID’d With Very Low Mortality
Younger age at diagnosis, Clark level II linked to low risk for death among patients with stage I lesions, negative clinical nodes.
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