Acalabrutinib Plus Rituximab “Highly Effective” in Older MCL Patients
Acalabrutinib and rituximab can yield early complete responses in older patients with previously untreated mantle cell lymphoma.
Acalabrutinib and rituximab can yield early complete responses in older patients with previously untreated mantle cell lymphoma.
Research presented at the 2023 Tandem Transplantation and Cellular Therapy Meetings of ASTCT and CIBMTR demonstrated favorable results for various types of lymphoma.
Researchers sought to evaluate first-line treatment of patients with advanced-stage MCL who were younger than 66 years of age.
Researchers sought to determine whether rituximab maintenance therapy would have a clinical benefit in elderly patients with mantle cell lymphoma.
As a noncovalent inhibitor of BTK, pirtobrutinib is able to reestablish BTK inhibition in patients previously treated with covalent BTK inhibitors.
Adding ibrutinib to induction and maintenance after transplant improves failure-free survival in patients with mantle cell lymphoma, results of the TRIANGLE study suggest.
A real-world study provides a benchmark for survival in MCL patients for whom BTK inhibitor treatment has failed, according to researchers.
Researchers sought to determine whether first-line rituximab plus bendamustine followed by ASCT would be an effective treatment option for MCL.
Researchers sought to determine the role and utilization of ASCT in younger patients with MCL.
Initial treatment of mantle cell lymphoma with lenalidomide and rituximab may result in significant complete response rates and durable lengths of remission.