Lenalidomide Maintenance Therapy May Be Best Treatment for Newly Diagnosed Multiple Myeloma
A meta-analysis of 11 studies rated the efficacy of 8 maintenance therapies with lenalidomide in combination or as monotherapy for NDMM.
A meta-analysis of 11 studies rated the efficacy of 8 maintenance therapies with lenalidomide in combination or as monotherapy for NDMM.
In this study, maintenance therapy with bortezomib plus thalidomide was compared with thalidomide alone or interferon alfa-2b alone in patients with newly diagnosed symptomatic multiple myeloma. Study findings demonstrate an impact on progression-free survival.
A longer duration of lenalidomide maintenance therapy after autologous HSCT may improve progression-free and overall survival in patients with multiple myeloma.
A first-line triplet chemoimmunotherapy regimen comprised of paclitaxel, capecitabine, and bevacizumab followed by capecitabine and bevacizumab alone as maintenance therapy is highly active with a manageable safety profile in patients with triple-negative breast cancer.