COSMIC-313: Triplet Prolongs PFS vs Doublet in Renal Cell Carcinoma
The PFS benefit was driven primarily by patients with intermediate-risk disease.
Diagnosis & Disease Information
Immune Checkpoint Inhibitor Therapy Linked With Improved Quality of Life
Among patients with a variety of solid tumors, investigators found favorable associations of immune checkpoint inhibitor therapy with quality of life compared with no immunotherapy use.
Normonatremia Tied to Outcomes in Metastatic Renal Cell Carcinoma
Serum sodium levels in the lower end of the normal range are associated with inferior outcomes in metastatic renal cell carcinoma, a study suggests.
Estimating Post-Nephrectomy GFR May Guide Treatment Decisions
An accurate estimate of future GFR after nephrectomy would help to guide operative strategy and use of adjuvant or neoadjuvant therapies, according to a recent editorial.
Reduced Initial TKI Dose Comparable to Full Dose in Metastatic Renal Cell Carcinoma
Researchers sought to determine if reducing the starting dose of TKI therapy in patients with metastatic RCC would improve tolerability without reducing efficacy.
Kidney Failure Risk Higher After Kidney Cancer Surgery
Investigators report a cumulative 10-year incidence of end-stage kidney disease of 2.5% among patients who undergo surgery for renal cell carcinoma (RCC), which is 10 times higher than in patients without RCC.
Obesity Is Associated With Increased Risk for Renal Cell Carcinoma
New findings challenge the notion of an obesity paradox with regard to cancer-related survival.
Imaging Response to Immunotherapy Combination Therapies in mRCC
Investigators report findings from the largest analysis characterizing objective imaging response among patients with mRCC treated in routine clinical practice.
Dialysis Population Has Excess Cancer Mortality
Patients on dialysis die from cancer at twice the rate as those of the same age and sex in the general population, a study found.
Kidney Cancer Metastases Effectively Treated With Robotic Radiosurgery
Investigators examined outcomes of robotic radiosurgery in patients with lung, visceral, and lymph node metastases from renal cell carcinoma.
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