Long-Term Data Support Frontline Avelumab and Axitinib for Advanced RCC
Combination avelumab and axitinib has shown long-term activity in previously untreated patients with advanced renal cell carcinoma.
Diagnosis & Disease Information
Cryoablation More Effective for Some Early-Stage Renal Cell Carcinomas
Increased cancer-specific mortality seen with heat-based thermal ablation versus cryoablation for tumor size 3.1 to 4 cm.
Cytoreductive Nephrectomy Added to ICI Therapy Ups Survival in mRCC
Use of cytoreductive nephrectomy with an immune checkpoint inhibitor reduced death risk by 67%.
Proteinuria, AKI With New Tyrosine Kinase Inhibitors Characterized
Since FDA approval of imtainib, 40 newer tyrosine kinase inhibitor agents have been approved.
Researchers Characterize Gut Microbiome of Patients With mRCC and Sarcopenia
Sarcopenic patients with metastatic renal cell carcinoma have distinct bacterial populations that express metabolic pathways associated with a catabolic state.
Pediatric Cancer Patients Treated With RT May Have Increased Risk of Meningioma for 30 Years
Patients who undergo radiotherapy for the treatment of childhood cancer have an increased risk of developing meningioma later in life, and that risk may persist for 30 years.
Adaptive Nivolumab Plus Ipilimumab Improves Outcomes in mRCC
Final results from the TITAN-RCC trial demonstrate improvements in objective response rates compared with nivolumab monotherapy.
Real-World Data Support Nivolumab + Ipilimumab for First-Line mRCC Therapy
Study revealed an objective response rate consistent with that observed in the CheckMate 214 clinical trial and a low rate of treatment-related adverse events.
Prevalence of Adrenal Tumors Modest Despite Significant Increase in Detection
Researchers sought to understand the significance of increasing detection rates of adrenal tumors due to improved imaging technologies.
Adjuvant Nivolumab + Ipilimumab Lacks Efficacy for Localized RCC
Trial did not meet primary efficacy end point of disease-free survival in patients with localized RCC at high risk for postnephrectomy relapse.
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