Eltrombopag: Noninferior to Intravenous Immunoglobulin in Immune Thrombocytopenia?
Eltrombopag may be an effective alternative to intravenous immunoglobulin for the perioperative treatment of immune thrombocytopenia.
Diagnosis & Disease Information
Mini-Pools of IVIG Just as Effective as Standard IVIG in Pediatric Immune Thrombocytopenia
Intravenous immunoglobulin G with plasma from fewer blood donations provides sufficient therapeutic effect for pediatric patients with ITP.
Patients, Physicians Do Not Recognize Fatigue the Same
A worldwide survey reveals that despite similar perceptions on symptom burden of ITP, patients and physicians do not agree on the effect of fatigue on quality of life.
Infections in Primary Immune Thrombocytopenia Associated With Low Platelet Count
A retrospective study of platelet- and infection-related data from patients with ITP revealed the influence platelet levels have on infections as well as efficacy of transfusions.
Fostamatinib Appears Effective for Immune Thrombocytopenia
Researchers found that stable responses occurred in 18 percent of patients on fostamatinib, versus 2 percent on placebo.
Interim Data Shows Romiplostim May Lead to Positive Long-Term Response in Pediatric ITP
In a poster presentation at the 23rd Congress of EHA, researchers described a study of the efficacy of romiplastim in achieving a platelet response in pediatric patients with immune thrombocytopenia.
FDA Approves Fostamatinib for ITP After Insufficient Response to Previous Treatment
The US FDA granted approval to fostamatinib (Tavalisse), a kinase inhibitor, for the treatment of thrombocytopenia in patients with chronic IPT who have had an insufficient response to a previous treatment.
Cardiovascular Disease Risks Greater With ITP, Especially After Splenectomy
Idiopathic thrombocytopenic purpura (ITP) may be linked to an increased risk of cardiovascular disease, but studies have not been conclusive.
ITP Treatment Outcomes Not Improved With Intravenous vs Oral Corticosteroids
In this prospective study, researchers sought to compare the effectiveness of IV methylprednisolone vs oral prednisone in hospitalized patients with newly diagnosed ITP.
High-Dose Dexamethasone Effective With Less Adverse Effects in ITP vs Corticosteroids
In this randomized trial, investigators sought to determine the effectiveness of high-dose dexamethasone vs conventional prednisone therapy in treatment-naïve patients with ITP. Results were presented at ASH 2017.
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