Hematopoietic Stem Cell Transplantation Archives

Adding Eprenetapopt to Maintenance Azacitidine Promising After HCT in MDS/AML

By

May 9, 2022

Researchers sought to determine whether adding eprenetapopt to maintenance azacitidine after HCT would be effective in patients with AML or MDS.

ONS Annual Congress 2022

Validation of Nursing Skills Improves Central Line Infection Rates on HSCT Unit

By

Joyce Pagan

May 3, 2022

A project to reverse an increase in CLABSIs on an HSCT inpatient unit and its ongoing impact were described at the Annual ONS Congress.

Hematologic Cancers

AAD: Skin Videomicroscopy Biomarker May Help Predict Cancer Relapse

April 11, 2022

Assessment of leukocytes adherent to and rolling along vessel wall may help predict outcomes after HCT for hematologic cancer.

Multiple Myeloma

STEPS Program After HCT for Multiple Myeloma Is Useful Measure of Patient Status

By

Vicki Moore, PhD

October 21, 2021

The physical activity intervention was a feasible and accepted program for patients with MM after hematopoietic cell transplantation, and provided useful information regarding patient recovery.

Side-Effect Management

Incidence of Cardiac Toxicities With GVHD Prophylaxis After AlloHCT

By

Jennifer Larson

October 7, 2021

An analysis determined the potential for posttransplant cyclophosphamide prophylaxis for GVHD in patients who underwent alloHCT.

Over half of evaluable patients who received an infusion of tisagenlecleucel achieved response.

Lymphoma

Hypomagnesemia at Time of Transplant Associated With Worse Survival in Patients With DLBCL

By

Jonathan Goodman, MPhil

April 21, 2021

Researchers sought to determine whether hypomagnesemia increases the risk of failure for autologous hematopoietic stem cell transplantation in patients with DLBCL.

Final results of a landmark trial confirm the efficacy of ibrutinib for CLL and SLL—and while cardiovascular issues remain a concern, the benefits appear to outweigh the risks.

Side-Effect Management

Classifying Patient Reponses to Steroid Therapy for Acute GVHD May Improve Outcomes

By

Jennifer Larson

April 15, 2021

Researchers identified classifications of acute graft-versus-host-disease to facilitate better management of the adverse effect in patients who undergo hematopoietic cell transplant.

Hematologic Cancers

Improvements Seen in Allogeneic Stem Cell Transplantation-Related Mortality

By

Jonathan Goodman, MPhil

January 8, 2021

Experts assessed mortality rates linked to allogeneic stem cell transplantation in the past 40 years using data from the European Society for Blood and Marrow Transplantation registry.

Multiple Myeloma

Novel Prognostic Model to Predict Survival in Multiple Myeloma Undergoing Autologous Hematopoietic Stem Cell Transplantation

By

Jonathan Goodman, MPhil

November 10, 2020

A novel scoring system for patients with MM undergoing upfront autologous HSCT appears predictive of both progression-free survival and overall survival.