Triplet Maintenance Extends PFS After Transplant in Multiple Myeloma
Phase 3 trial results support the use of carfilzomib, lenalidomide, and dexamethasone as maintenance after autologous stem cell transplant in patients with multiple myeloma.
Diagnosis & Disease Information
Early Active Treatment Strategies Improve Outcomes in Newly Diagnosed High-Risk Myelodysplastic Syndrome
Researchers sought to determine whether early treatment strategies would be beneficial in patients with newly diagnosed, high-risk MDS.
Posoleucel Deemed Effective Against Viral Infections in Allogeneic HSCT Recipients
Posoleucel appears safe and effective for treating refractory viral infections occurring after allogeneic hematopoietic stem cell transplant.
Low-Dose Melphalan Achieves Survival Outcomes, Relapse Rates Similar to Standard Dose
Researchers compared outcomes for patients with multiple myeloma who received conditioning regimen of melphalan at a lower dose with outcomes using the standard dose.
PTCy Plus Tacrolimus and MMF “Should Be Standard” GVHD Prophylaxis in RIC PBSCT
PTCy plus tacrolimus and MMF should be standard GVHD prophylaxis in adults who receive a well-matched PBSCT after RIC, according to researchers.
Correlating Endoscopic Findings and Histologic Signs of GVHD in Upper GI Tract
A retrospective analysis of biopsies sought to correlate histologic findings with endoscopic findings in patients with upper GI tract GVHD after allogenic HSCT.
Feasibility of Enteral Nutrition Pathway Implantation Limited in Pediatric HSCT
An evidence-based practice quality improvement project sought to determine the need, benefits, and challenges to implementing enteral nutrition in children undergoing hematopoietic stem cell transplantation.
Novel Monoclonal Antibody a Potential Treatment for Refractory Chronic GVHD
Results of a phase 1/2 study determine the dosing, safety, and efficacy of axatilimab for refractory chronic graft-vs-host disease.
Diet Not Associated With Infection Risk in Patients With Neutropenia After HSCT
Randomized noninferiority study compared outcomes for patients with neutropenia after HSCT who followed a protective diet with those who followed a nonrestrictive diet.
Coping Strategies Linked to Distress, QOL in Caregivers of Stem Cell Recipients
Caregivers with approach-oriented coping strategy have less anxiety and depression symptoms, better quality of life.
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