Gavreto Gets Accelerated Approval for RET-Altered Thyroid Cancers
The approval was based on data from the phase 1/2 ARROW trial which evaluated the efficacy and safety of Gavreto in patients with RET-mutant MTC.
Head and Neck Cancer
Statistical Index Suggests That Many ICI Trials Show Uncertain Clinical Benefit
The survival-inferred fragility index of phase 3 trials for immune checkpoint inhibitors suggests that, despite statistical significance, survival data do not show a robust clinical benefit.
Head and Neck Cancers Treatment Regimens
View detailed treatment regimens for head and neck cancers, with options such as cisplatin, cisplatin + radiotherapy, and more.
Experts Establish Surgical Priority Ranking for Head and Neck Cancers
Experts have developed a new tool for surgical prioritization and ranking for patients with head and neck cancer in a scarce-resource settings associated with the COVID-19 pandemic.
RET Inhibitor Demonstrates Efficacy in RET-Altered Thyroid Cancer
Treatment of RET-altered thyroid cancer with selpercatinib, a RET inhibitor, resulted in durable efficacy with a tolerable safety profile in a phase 1/2 trial.
Transoral Robotic Surgery Ups Survival in Oropharyngeal Cancer
Outcomes and survival improved for early-stage oropharyngeal cancer, but not other cancers.
Weight and Swallowing-Related Quality of Life in Patients Treated for Oropharyngeal Cancer
Single-center study reports on the effects of oropharyngeal cancer treatment at 3, 6, and 12 months after chemoradiotherapy or radiotherapy alone, and with and without a feeding tube.
Adding Radiotherapy to Chemotherapy Boosts Survival in Nasopharyngeal Carcinoma
Patients treated with chemotherapy plus radiotherapy had a 64% reduced likelihood of disease progression or death compared with those who underwent chemotherapy alone.
A 6-Gene Expression Signature May Predict Benefit From Induction Chemotherapy in Locally Advanced Nasopharyngeal Cancer
The purpose of this study was to develop and test a gene-expression profiling assay to facilitate patient selection for induction chemotherapy in the setting of LA-NPC.
Increasing Trends in Thyroid Cancer Burden Since 1990 Observed Worldwide
Increasing trends in global thyroid cancer burden were observed in a cross-sectional study using data from 195 countries in 21 regions.
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