Outcomes Superior With Peripheral Blood vs Bone Marrow Transplants in PTCL
A retrospective analysis sought to determine safety and tolerability of posttransplantation cyclophosphamide in patients with peripheral T-cell lymphoma.
Diagnosis & Disease Information
PTCy Plus Tacrolimus and MMF “Should Be Standard” GVHD Prophylaxis in RIC PBSCT
PTCy plus tacrolimus and MMF should be standard GVHD prophylaxis in adults who receive a well-matched PBSCT after RIC, according to researchers.
Correlating Endoscopic Findings and Histologic Signs of GVHD in Upper GI Tract
A retrospective analysis of biopsies sought to correlate histologic findings with endoscopic findings in patients with upper GI tract GVHD after allogenic HSCT.
Novel Monoclonal Antibody a Potential Treatment for Refractory Chronic GVHD
Results of a phase 1/2 study determine the dosing, safety, and efficacy of axatilimab for refractory chronic graft-vs-host disease.
High Risk for Mortality, Complications in Patients With SJS/TEN-Like aGVHD
Study authors assessed the clinicopathology, complications, and outcomes of patients with Steven-Johnson Syndrome (SJS)- and toxic epidermal necrolysis (TEN)-like acute graft-vs-host disease (aGVHD).
UCBT With FM-Based Reduced-Intensity Conditioning Improved Survival in Lymphoma
Researchers sought to determine whether UCBT with FM-based reduced-intensity conditioning would improve survival outcomes in patients with lymphoma.
Long-Term Outcomes Worse After Recovery From Severe Acute Graft-versus-Host Disease
A retrospective chart review demonstrated the long-term outcomes for patients with a history of grade 3-4 acute GVHD, compared with grade 0-1, after hematopoietic cell transplantation.
GVHD Grade at Diagnosis Correlates With Disease Progression, Overall Survival
A multicenter study sought to determine the rate of progression to a higher grade among patients who develop acute GVHD after undergoing hematopoietic stem cell transplantation.
Late Effects With Chronic GVHD in Children After Hematopoietic Cell Transplantation
Researchers sought to determine the effect of chronic graft-versus-host disease on late effects after HCT in pediatric cancer survivors.
PTCy With Tacrolimus Safe, Effective at Reducing GVHD in Older Patients With Hematologic Cancers
Researchers sought to determine the safety and efficacy of posttransplantation cyclophosphamide with tacrolimus as prophylaxis for GVHD in patients with hematologic cancer after allogeneic hematopoietic cell transplantation.
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