Genomic Alterations Distinct for Black Men With Prostate Cancer
Frequencies of genomic alterations in current therapeutic targets similar for AFR, EUR men.
Diagnosis & Disease Information
Advances in Radiogenomics: A Review
Researchers are seeking genetic biomarkers that can predict which patients are most likely to suffer radiotoxicities and which can safely undergo intensified radiation treatment regimens.
Metabolism of Next-Generation Prostate Cancer Drugs Share Similarities
How the body metabolizes next-generation anti-androgen agents affects their anti-tumor activity in the treatment of prostate cancer.
Personalized Medicine and the Role of the Oncology Navigator
As molecular testing becomes the standard of care for many cancers, nurse navigators have an important role to play ensuring molecular testing of suitable patients, providing patient education, and managing of patient expectations.
Genome-Informed Treatment Improves Survival in Pancreatic Cancer
Precision Medicine Improves Pancreatic Cancer Treatment
Analysis & Perspective on Practical and Ethical Use and Interpretation of Whole Genome Sequencing Data During Clinical Trials
Despite the value of genomic sequence information, nurses need to be aware of the limitations of this information and ethical concerns regarding sharing it with patients.
E4 Steroid Reduces Testosterone Levels, Treats Advanced Prostate Cancer
Steroid produced by human fetal liver reduces testosterone levels, holding potential as treatment for advanced prostate cancer.
Protein Suppresses Transformation of Myelodysplastic Syndrome to Acute Myeloid Leukemia
Research on the transformation of MDS to AML identifies a protein whose deletion is a potential tumor suppressor that would block this disease progression.
Genetic Similarity to BRCA1/BRCA2 Mutations May Impact Treatment Options
Genetic signatures similar to BRCA1/BRCA2 mutations could make PARP inhibition a treatment option for some breast cancers.
Genome Sequencing Explains Resistance to CTLA-4 and PD-1 Inhibitors in Metastatic Melanoma
Whole-exome sequencing of tumor biopsies explain low response rate to immunotherapy in metastatic melanoma.
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