Experimental drug shrinks melanoma tumors
Dabrafenib, which targets a genetic mutation that is active in half of melanoma cases, substantially and safely shrank metastatic tumors.
Diagnosis & Disease Information
Melanoma genome study implicates sun and new genetic culprits
Genetic mutations increased along with chronic sun exposure in persons with melanoma, and yet another gene may contribute to disease risk as well.
Modified stem cells keep glioblastoma at bay
Three patients with glioblastoma lived longer than predicted after receiving transplants of their own blood stem cells that had been gene-modified.
Gene anomaly can predict behavior of prostate cancer
A specific genomic abnormality found in either benign or malignant prostate tissues is predictive of the clinical outcome of prostate cancer.
More chemotherapy might be best move for some children with leukemia
When induction therapy fails in acute lymphoblastic leukemia, some youths have better outcomes with more chemotherapy than with stem cell transplant.
Study will compare stool DNA screens with colonoscopy
Researchers at Seidman Cancer Center in Cleveland are recruiting patients for a study of a new, noninvasive technology for colon cancer screening.
Experimental agent acts against aggressive lymphoma subtype
The drug ibrutinib can provide significant anticancer responses with modest side effects in persons with diffuse large B-cell lymphomas (DLBCLs).
Mutations in XRCC2 gene tied to breast cancer risk
Mutations in a gene called XRCC2 have been linked to breast cancer susceptibility in families with none of the currently known breast-risk genes.
New marker flags DNA repair response to platinum therapy
A new marker of DNA damage may predict which triple-negative breast cancers or serous ovarian cancers will respond to platinum-based chemotherapy.
Stress management boosts immune system in breast cancer
A stress-management program for women with breast cancer can alter tumor-promoting processes at the molecular level, according to researchers.
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