Frontline Pembrolizumab Improves PFS, OS in HER2- Gastric/GEJ Cancers
Adding pembrolizumab to frontline chemotherapy improves outcomes in patients with HER2-negative, advanced gastric or GEJ cancers, a phase 3 trial suggests.
Diagnosis & Disease Information
Improving End-of-Life Discussions With Cancer Patients
Timely discussions about end-of-life preferences can ensure patients with advanced cancer receive care that aligns with their goals, experts say.
Precision Medicine Can Be Integrated Into Routine Cancer Care
Implementation of precision oncology recommendations has clinical utility for patients with gastrointestinal cancers.
Esophageal, Gastric Cancer Risks Reduced With Bariatric Surgery for Obesity
Researchers explored the potential relationship between bariatric surgery for severe obesity and risk of esophageal and gastric cancers.
Accuracy of Prognostic Score System for Advanced Gastroesophageal Cancer Analyzed
Researchers sought to determine which of 4 well-known prognostic scoring systems were more accurate in patients with advanced GE cancer.
Trimodality Therapy Reduces Risk of Death for Older Adults With Esophageal Cancer
The 5-year cumulative incidence of cancer-specific mortality was lower with trimodality therapy than with definitive chemoradiation in patients with adenocarcinoma and squamous cell carcinoma.
FOLFOX, Nivolumab, Trastuzumab Fares Best in ERBB2-Positive Gastric Cancer
A chemotherapy-containing regimen appears more effective than a chemotherapy-free regimen as first-line therapy for ERBB2-positive gastric cancer.
Survival Similar for Early, Delayed Surgery in Stage I Esophageal Cancer
For patients with stage II/III esophageal cancer, five-year survival is improved with early versus delayed esophagectomy.
Esophageal Cancer Incidence on the Rise in Middle-Aged Adults
The incidence of esophageal cancer nearly doubled, and this was not due to an increase in screening.
Second-Line Tislelizumab Prolongs OS in Advanced Esophageal Squamous Cell Carcinoma
Tislelizumab reduced the risk of death by 30%, when compared with chemotherapy.
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