Zamtocabtagene Autoleucel Produces High ORR in Relapsed/Refractory DLBCL
Zamtocabtagene autoleucel produced responses in patients with relapsed/refractory diffuse large B-cell lymphoma in a phase 2 trial.
Diagnosis & Disease Information
“Severe4” Predicts Outcomes of CAR T-Cell Therapy in Relapsed/Refractory DLBCL
A prognostic index called “Severe4” can predict outcomes of CAR T-cell therapy in patients with relapsed/refractory DLBCL, a study suggests.
Chronotherapy Study Shows Afternoon Regimens Better for Female Patients With DLBCL
A study evaluating the use of chronotherapy for hematologic cancers identifies how the approach can improve outcomes for some patients.
Outcomes for R-CHOP Worse in Morning for Female Patients With Lymphoma
Progression-free, overall survival significantly lower for female patients receiving chemo mostly in morning.
Routine Use of Axicabtagene Ciloleucel Could Be Cost Effective in Relapsed/Refractory Diffuse Large B-Cell Lymphoma
Researchers sought to determine whether the use of second-line CAR-T therapy could be cost effective in DLBCL.
Atezolizumab Plus R-CHOP Deemed Unworthy of Additional Study in Diffuse Large B-Cell Lymphoma
Results of a phase 1/2 trial suggest the combination of atezolizumab and R-CHOP does not warrant further study in DLBCL, according to researchers.
Long-Acting G-CSF May Reduce FN-Related Hospitalization in DLBCL After R-CHOP
Long-acting G-CSF can reduce the risk of hospitalization related to febrile neutropenia in patients with DLBCL treated with R-CHOP.
Orelabrutinib Plus RCHOP Effective for Extranodal, Non-GCB Diffuse Large B-Cell Lymphoma
The aim of this trial was to evaluate the efficacy and safety of orelabrutinib with RCHOP in patients with extranodal non-GCB DLBCL.
Genomic Features and Anti-CD19 CAR-T Therapy Failure in Large B-Bell Lymphoma
Researchers sought to identify genomic features in patients with large B-cell lymphoma that are linked with anti-CD19 CAR-T therapy.
Coagulation Parameters With Cytokine-Release Syndrome and CAR-T Therapy in B-Cell Lymphomas
Researchers sought to determine patterns in coagulation parameters linked to cytokine-release syndrome in patients receiving CAR-T therapy.
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