Mutations in IDH1/2 Seen in Intrahepatic Bile Duct Cancers
Mutations found in about a quarter of cholangiocarcinomas of intrahepatic origin.
Diagnosis & Disease Information
Radiation Benefits Mixed After Breast-Preserving Surgery
Radiation therapy slightly improves survival, but may increase likelihood of eventual mastectomy.
Bevacizumab Efficacious for HER2-Negative Breast Cancer
Two studies show improved pathologic complete response with addition of bevacizumab.
ASCO Gastrointestinal Cancers Symposium, Jan. 19-21, 2012
The American Society of Clinical Oncology’s ninth annual Gastrointestinal Cancers Symposium was held from Jan. 19 to 21 in San Francisco; several highlights are detailed.
BRCA Carriers Have Improved Survival in Ovarian Cancer
For patients with invasive epithelial ovarian cancer (EOC), BRCA1 and BRCA2 mutations are associated with improved five-year survival, according to a study.
More Adverse QOL Issues in Young Breast Cancer Patients
Younger women with breast cancer experience increased psychological distress, fertility-related concerns, and decreased physical activity, a new review found.
Oxaliplatin Improves Survival for Colorectal Cancer Patients
Improvements found in community settings, even amongst older and minority populations.
New Pathway Inhibits TRAIL Apoptosis in Glioblastomas
A20 ligase mediates ubiquitination to inhibit caspase-8 cleavage and TRAIL-induced apoptosis, according a study published online in Cancer Discovery.
Imaging May Spare Nerves in Prostate Cancer Surgery
Preoperative MRI led to a change in surgical plan in 27 percent of robot-assisted prostatectomies.
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