Molecular Features May Predict Response in Primary Pancreatic Cancer
The goal of this study was to determine how molecular features change when PDAC progresses from a primary tumor to metastatic disease.
Diagnosis & Disease Information
Leukemia Risk in Children, Maternal Use of Hormonal Contraception Linked in Population Study
A prospective cohort study from Denmark investigated the link between maternal hormonal contraception use before — more than 3 months and within 3 months — and during pregnancy and risk of leukemia in their children.
Barriers to Prostate Cancer Research in Black Men Identified
Mistrust, lack of knowledge, unfavorable attitudes are barriers to genomic testing, study participation
New Method Estimates Risk for Breast Cancer Recurrence
Higher recurrence risk linked to older age, more advanced stage, HR-negative tumors.
CheckMate 067 Gives Nivolumab Alone, With Ipilimumab the Nod in Advanced Melanoma
Survival and progression-free survival were better with nivolumab alone or with ipilimumab vs ipilimumab alone for stage III or IV melanoma with known BRAFV600 mutation, according to results of this randomized study.
PACC Guidelines Recommend IT Morphine, Ziconotide for Chronic Pain
The 2016 evidence-based PACC guidelines recommend the use of morphine and ziconotide as effective and safe first-line IT monotherapies for chronic pain.
ASCO, SITC Release Recommendations for Clinical Trial Reporting of Immunotherapy Adverse Events
As immunotherapies gain a stronger foothold as a treatment option for cancer, ASCO and SITC convened a panel to develop recommendations to ensure consistent and efficient clinical trial reporting in immuno-oncology.
Dietary Habits May Prolong Survival in Patients With Colorectal Cancer
A prospective analysis of diets before and after diagnosis revealed dietary habits among patients with colorectal cancer that may help prolong survival.
Risk Factors for Higher-Grade Transformation in Marginal Zone Lymphomas Identified
In a retrospective evaluation, investigators sought to identify risk factors for higher-grade transformation in patients with marginal zone lymphomas.
Standardization Could Improve Tumor Board Interpretation, Recommendations
Using fictional patient profiles and a questionnaire on recommendation procedures, researchers were able to demonstrate a need for standardized tumor board interpretation and recommendation processes worldwide.
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