Intensive Chemotherapy Tolerable, Efficacious in HIV-Associated Burkitt Lymphoma
Among patients with HIV-associated Burkitt lymphoma, intensive regimens containing rituximab may be linked to favorable survival outcomes.
Among patients with HIV-associated Burkitt lymphoma, intensive regimens containing rituximab may be linked to favorable survival outcomes.
While the rate of certain HIV-linked non-Hodgkin lymphomas has declined since the introduction of ART, the incidence of Burkitt lymphoma has remained steady.
Dose-adjusted EPOCH-R resulted in higher tolerance and efficacy among adults with Burkitt lymphoma.
Researchers assessed data from Australian population-based lymphoma registries to determine the efficacy of intensive immunochemotherapy for Burkitt lymphoma.
Cancer, particularly non-Hodgkin lymphoma, remains a leading cause of death in patients with HIV who are being treated with antiretroviral therapy.
Older age is associated with worse prognosis in patients with early-stage Burkitt lymphoma, according to study authors.
A link between malaria and Burkitt’s lymphoma was first described more than 50 years ago, but how a parasitic infection could turn immune cells cancerous has remained a mystery. Now, researchers have demonstrated in mice that B cell DNA becomes vulnerable to cancer-causing mutations.
Adult patients with Burkitt lymphoma had excellent long-term survival rates—upwards of 90%—following treatment with low-intensity chemotherapy regimens, according to a new clinical trial finding.
High rates of freedom from disease, overall survival for standard-dose, with lower-dose EPOCH-R treatment.
A new study that tracked survival during the last decade of more than 2,200 adults with a highly aggressive form of lymphoma has found that medicine has made substantial progress in treating them successfully, with notable exceptions.