Senior Patients With Cancer Can Benefit From Palliative Radiotherapy
Researchers evaluated whether age is a predictor of pain response after radiotherapy for painful bone metastasis among 128 patients undergoing palliative radiotherapy.
Diagnosis & Disease Information
Bisphosphonates vs Denosumab: Preventing SREs in Breast Cancer With Bone Metastasis
A comparison study presented at the 2017 SABCS sought to determine the effectiveness of bisphosphonates with denosumab for skeletal-related events in women with breast cancer metastases to bone.
Updated ASTRO Guideline Bolsters Safety, Efficacy of Palliative RT for Bone Metastases
Palliative radiotherapy for bone metastases is safe, effective — but controversy persists for single-fraction treatment.
QoL, Pain from Bone Metastases May Improve as Early as 10 Days After RT
A single 8-Gy dose of radiotherapy for painful bone metastases may improve quality of life and pain as early as 10 days after administration.
Longer Dosing Interval of Zoledronic Acid May Be Acceptable for Bone Metastases
Results from a phase 3 trial comparing a 12-week dosing interval with the standard 4-week dosing interval of zoledronic acid to reduce the incidence of skeletal-related events and pain in patients with bone metastases.
New Therapy Blocks Breast Cancer Cells From Entering and Hiding in Bone Marrow to Form Latent Metastases
Researchers demonstrate how breast cancer cells invade bone marrow, where they escape chemotherapy and hormonal therapies that would otherwise eliminate the cancer cells.
Skeletal-related Events Linked With Worse Survival, Increased Costs
Men with prostate cancer and bone metastases that have experienced at least one skeletal-related event (SRE) show worse survival, according to a recent study.
Tumor Location and Duration of Therapy Influence Palliative Effects of Radiation Therapy for Painful Bone Metastases
In a review of the Dutch Bone Metastasis Study results, stratified for primary tumor location, palliative radiation therapy was found to reduce pain and improve quality of life for some patients.
Researchers Find Pathway to Cancer-Associated Muscle Weakness
Cancer researchers have identified the molecular pathways that lead to cancer-associated muscle weakness. When they inhibited TGF-β, muscle function improved in mouse models of human cancers.
Process of metastasis to bone in breast cancer is identified
A new study may have uncovered the key to the early detection of patients at risk of developing metastasis to bone.
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