IDH gene may serve as prognostic marker in anaplastic astrocytoma
New research indicates that the IDH1 gene might be a prognostic marker for a rare form of brain cancer.
Diagnosis & Disease Information
Gene mutation defines brain tumors that benefit from aggressive surgery
Patients with malignant astrocytoma whose tumors carry the gene mutation IDH1 may benefit greatly from surgical removal of the largest possible amount of tumor.
Brain tumors in children have a common cause
When 96 pilocytic astrocytomas were analyzed by whole-genome sequencing, all had MAPK-pathway alterations. This indicates that pilocytic astrocytoma is predominantly a single-pathway disease.
Genetic pathways may suggest more effective targeted therapies for childhood brain tumors
A new study offers glimpses into how scientists will be using the ongoing flood of gene-sequencing data to customize treatments based on very specific mutations in a child’s tumor.
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