Exposure to Antibiotics Associated With Survival Detriment in Patients With Advanced Melanoma Treated With ICIs
Previous studies have shown an association between gut microbiome diversity and response to immune checkpoint inhibitor therapy.
Diagnosis & Disease Information
New antibiotic and method for developing it exploits microbes’ natural environment
Researchers have discovered a powerful new antibiotic, teixobactin, using an unusual method.
Adverse effects of amoxicillin may be potentially under-reported
Researchers conducted a review of controlled trials to assess potential harms related to amoxicillin use.
HF/CM risks in breast chemotherapy
Earlier study findings that anthracycline- or trastuzumab-based treatment for breast cancer raises the risk for heart failure and cardiomyopathy can be extended to a more general population of women.
Benefits of using probiotics
What are the benefits of probiotics? Does any particular kind offer more benefits than the others?
Addition of vorinostat yields high remission rate in AML study
An 85% remission rate was noted in a group of patients with acute myeloid leukemia who received the histone deacetylase inhibitor vorinostat in addition to cytarabine and idarubicin.
Existing antibiotic may help fight leukemia
The IV antimicrobial tigecycline, indicated for the treatment of various infections, targets and destroys leukemia stem cells by cutting off the cell’s energy production.
Bleomycin test dose
Should patients receive a test dose of bleomycin? If yes, should the test dose be administered with every dose or just the initial dose?
FoxM1 protein may hold key to treatment of pediatric brain tumor
The regulatory protein FoxM1 is essential for the continued growth of medulloblastoma and is significantly and negatively correlated with survival, making it a useful prognostic marker.
New monoclonal antibody is a “source of hope” for patients with metastatic melanoma
A recently FDA-approved treatment and an experimental BRAF inhibitor offer hope to patients with metastatic melanoma.
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