Skin Cancer

AAD Releases New Guidelines for the Treatment of Cutaneous Melanoma

AAD Releases New Guidelines for the Treatment of Cutaneous Melanoma

Guidelines recommend surgical excision as primary treatment modality, and emphasize individualized care.

Novel Immunotherapy May Increase Survival in Melanoma Brain Metastases

Novel Immunotherapy May Increase Survival in Melanoma Brain Metastases

Researchers used data from the National Cancer Database to evaluate the overall survival of patients who presented with cutaneous MBM from 2010 to 2015.

Skin Cancer Screening Programs: Are They Effective?

Skin Cancer Screening Programs: Are They Effective?

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Skin cancer screening programs have led to diagnoses of melanoma that would have otherwise been missed, but the overall public health benefit of such programs remains unclear.

SD-101 May Enhance the Effectiveness of Immunotherapy in Melanoma

SD-101 May Enhance the Effectiveness of Immunotherapy in Melanoma

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In this phase 1b study, researchers evaluated the efficacy of immunotherapy with pembrolizumab to treat advanced melanoma.

Red Hair Variants of <i>MC1R</i> Influence Melanoma Risk Differently in Men, Women

Red Hair Variants of MC1R Influence Melanoma Risk Differently in Men, Women

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Multivariate logistic regression analyses were utilized by researchers to evaluate the effect of MC1R and melanoma risk in men vs women.

Assessing Direct Costs of Treatment-Related Adverse Events in Advanced Melanoma

Assessing Direct Costs of Treatment-Related Adverse Events in Advanced Melanoma

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In a systematic review, researchers explored the financial burden of treating grade 3 to 4 adverse events associated with melanoma and its treatment.

Is Radioimmunotherapy a Path Forward for Melanoma?

Is Radioimmunotherapy a Path Forward for Melanoma?

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Recent research implicates patients' immune cells appear to stimulate radiation abscopal effects, raising the possibility that combining radiotherapy and immunotherapy could yield previously-untapped treatment synergies to improve tumor control.

Frequency of Tanning, Risk for Melanoma Higher in Gym Tanners

Frequency of Tanning, Risk for Melanoma Higher in Gym Tanners

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The use of tanning beds and/or booths and their availability in gyms may increase the frequency of indoor tanning for physically active adults, a combination that further exacerbates their risk for melanoma.

Do Sunless Tanners Have Fewer Skin Cancer Risk Behaviors?

Do Sunless Tanners Have Fewer Skin Cancer Risk Behaviors?

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A cross-sectional study investigated the other skin cancer prevention habits of people who use sunless tanning to reduce their UV exposure.

Skinder App Helps Develop Skills in Intuitive Diagnosis of Melanoma

Skinder App Helps Develop Skills in Intuitive Diagnosis of Melanoma

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Medical students participating in this study were randomly assigned to either a rule-based or application group.

Anxiety Not Relieved With Handholding, Stress Ball Use During Skin Cancer Excision

Anxiety Not Relieved With Handholding, Stress Ball Use During Skin Cancer Excision

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Most dermatologic procedures are performed with local anesthesia only. In this study, researchers sought to determine if hand-holding or squeezing a stress ball could ease patients' anxiety during skin excision procedures.

Patient Interest in Melanoma Genetic Risk Testing is Fairly High

Patient Interest in Melanoma Genetic Risk Testing is Fairly High

Researchers examined interest in MC1R testing in the general population and assessed patterns across demographic and skin cancer risk factors.

Study Finds Association Between Folate Intake and Risk of Cutaneous Melanoma

Study Finds Association Between Folate Intake and Risk of Cutaneous Melanoma

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Researchers assessed the effect intake levels of folate and other nutrients involved in one-carbon metabolism have on risk of melanoma.

Melanoma Outcomes Improved With Nivolumab Alone or Plus Ipilimumab

Melanoma Outcomes Improved With Nivolumab Alone or Plus Ipilimumab

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Systemic review and meta-analysis evaluated the efficacy of nivolumab vs ipilimumab, in combination, as monotherapy, or vs other treatment options for the treatment of metastatic melanoma.

Oral Contraceptive Use May Not Be Associated With Increased Melanoma Risk

Oral Contraceptive Use May Not Be Associated With Increased Melanoma Risk

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Researchers sought to determine if melanoma risk was associated with oral contraceptive use or if OC users are more likely to have higher exposure to UV light.

Encorafenib, Binimetinib Combination Receives FDA Approval for Mutation-Positive Melanoma

Encorafenib, Binimetinib Combination Receives FDA Approval for Mutation-Positive Melanoma

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Approval was granted for the treatment of patients with unresectable or metastatic BRAF V600E or V600K mutation-positive melanoma.

Radiation, Immunotherapy Improved Median Overall Survival in Melanoma Brain Metastases

Radiation, Immunotherapy Improved Median Overall Survival in Melanoma Brain Metastases

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Study data indicate that checkpoint inhibitors combined with radiation could improve survival for patients with melanoma-related brain metastases.

New Guidelines Increase Melanoma Staging Reproducibility and Concordance

New Guidelines Increase Melanoma Staging Reproducibility and Concordance

Greater reproducibility and higher concordance for melanoma staging observed with implementation of AJCC 8.

Link Found Between Skin Cancer Risk and High Polyunsaturated Fat Intake

Link Found Between Skin Cancer Risk and High Polyunsaturated Fat Intake

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Using data from the NHS and the HPFS, researchers investigated the association between polyunsaturated fat, cholesterol, and monounsaturated fat intake and risks for SCC, melanoma, and BCC.

Lower Risk for Alzheimer Associated With Skin Cancer Diagnoses

Lower Risk for Alzheimer Associated With Skin Cancer Diagnoses

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After adjusting for confounding factors,a significantly decreased risk for subsequent AD was reported among patients with malignant melanoma.

New Recommendations Target Promoting Better Sun Protection Habits for All Patients

New Recommendations Target Promoting Better Sun Protection Habits for All Patients

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A new US Preventive Services Task Force Evidence Report is suggesting that greater efforts are needed to educate children and young adults with fair skin about risks of sun exposure. Although the Task Force recommendations are directed at primary care, its members are encouraging oncology nurses to take note of these new findings.

What Prompts Indoor Tanners and Nontanners to Undergo Skin Cancer Screening?

What Prompts Indoor Tanners and Nontanners to Undergo Skin Cancer Screening?

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Researchers sought to determine the factors that influenced a decision to undergo skin cancer screening among more than 30,000 adults who have ever used an indoor tanning device and nontanners.

Study Determined Association Between Risk of Melanoma, Aspirin Use

Study Determined Association Between Risk of Melanoma, Aspirin Use

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In a review of nearly 200,000 patients from a Midwest metropolitan area, researchers sought to determine if chronic aspirin use would offer the same risk reduction for melanoma as has been seen in various cancers.

Prognostic Indicator for Cutaneous Melanoma: SNLB vs Breslow Thickness

Prognostic Indicator for Cutaneous Melanoma: SNLB vs Breslow Thickness

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Investigators sought to compare the prognostic value of sentinel lymph node status vs Breslow thickness in patients with cutaneous melanoma.

USPSTF: Skin Cancer Counseling Recommended for Fair-Skinned Individuals

USPSTF: Skin Cancer Counseling Recommended for Fair-Skinned Individuals

The U.S Preventive Services Task Force recommends counseling for fair-skinned individuals younger than 24 years, and selective counseling is recommended for adults.

USPSTF: Behavioral interventions do not reduce sunburn or skin cancer outcomes

1. Behavioral interventions increase sun protection behavior but do not reduce sunburn or skin cancer outcomes. 2. Behavior interventions lead to increased skin self-examinations but may lead to additional skin procedures without finding additional skin cancers. Evidence Rating Level: 1 (Excellent) Study Rundown: While melanoma comprises 2% of all skin cancers, it causes more than []

Presence of Iris Pigmented Lesions Indicates Melanoma Risk

Presence of Iris Pigmented Lesions Indicates Melanoma Risk

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The likelihood for development of cutaneous melanoma may be greater for individuals with iris pigmented lesions, according to a study.

Revised AJCC8 Demonstrates Superior Tumor Classification for HNCSCC 

Revised AJCC8 Demonstrates Superior Tumor Classification for HNCSCC 

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AJCC8 tumor classification demonstrated significantly superior homogeneity and monotonicity to AJCC7 tumor classification.

Age Not a Deterrent to Immunotherapy for Malignant Melanoma

Age Not a Deterrent to Immunotherapy for Malignant Melanoma

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Investigators sought to evaluate whether age is associated with risk for immune-related adverse events among patients with metastatic melanoma treated with immunotherapy.

Adjuvant Vemurafenib Does Not Improve Disease-Free Survival in Melanoma

Adjuvant Vemurafenib Does Not Improve Disease-Free Survival in Melanoma

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Researchers report on finding of a double-blind phase 3 study on the efficacy of adjuvant vemurafenib in patients with resected stage IIC to IIIB melanoma.

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