Side-effect Management

Staff Education Leads to Increase in Oncology Rehabilitation Referrals

Staff Education Leads to Increase in Oncology Rehabilitation Referrals

Educational intervention for oncology clinicians at a rural Michigan oncology clinic does not demonstrate a statistically significant increase in referrals to rehabilitation; however, results show a clinically significant improvement in identification of need, communication among staff, and potential for greater referrals.

Data on Corticosteroid-Related Adverse Events in Advanced Cancer Are Lacking, Needed

Data on Corticosteroid-Related Adverse Events in Advanced Cancer Are Lacking, Needed

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Although corticosteroids are frequently used to manage adverse effects (AEs), data on AEs related to these agents are lacking. Therefore, these researchers sought to determine if better reporting of corticosteroid-related AEs would be of benefit.

Chinese Traditional Medicine Showed Effectiveness on Pain, Quality of Life in Advanced Cancer

Chinese Traditional Medicine Showed Effectiveness on Pain, Quality of Life in Advanced Cancer

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In a randomized study, researchers sought to determine the effect of IV injections of coix seed oil, a Chinese CAM, on pain and quality of life measures for patients with advanced cancer.

Handgrip Force May Provide Objective Evaluation of Cancer-Related Fatigue

Handgrip Force May Provide Objective Evaluation of Cancer-Related Fatigue

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Researchers sought to determine if handgrip force could provide objective measures of CRF in patients with cancer.

CALM: A Depression Intervention for Cancer Patients at the End of Life

CALM: A Depression Intervention for Cancer Patients at the End of Life

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The effectiveness of a novel intervention intended to reduce and/or prevent depression in patients with advanced cancer at the end of life was investigated in a randomized study with more than 300 patients.

PTSD May Increase Symptom Burden in Patients With Cancer

PTSD May Increase Symptom Burden in Patients With Cancer

Post-traumatic stress symptoms are linked to a greater symptom burden in hospitalized cancer patients.

Live or Online Mindfulness-Based Cognitive Therapy Reduced Cancer-Related Psychological Distress

Live or Online Mindfulness-Based Cognitive Therapy Reduced Cancer-Related Psychological Distress

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Mindfulness-based interventions are proven effective in helping patients with cancer manage distress and other psychological symptoms. In this study, researchers sought to determine if Internet-based MBCT can be as effective as face-to-face interventions.

Managing Dyspnea With Fentanyl in Patients With Cancer at End of Life

Managing Dyspnea With Fentanyl in Patients With Cancer at End of Life

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In this retrospective study, researchers sought to determine the effectiveness of fentanyl for dyspnea in dying patients with advanced cancer.

Muscle Loss Not Always Correlated With Loss of Function, Strength in Cancer Cachexia

Muscle Loss Not Always Correlated With Loss of Function, Strength in Cancer Cachexia

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Interventions specifically designed to target cachexia in patients with thoracic or gastrointestinal cancer and established cachexia were effective in helping patients preserve functional stability and rehabilitation potential.

Primary Prophylaxis Key in Reducing Febrile Neutropenia in Early Breast Cancer

Primary Prophylaxis Key in Reducing Febrile Neutropenia in Early Breast Cancer

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In a retrospective study, researchers investigated the effect of primary prophylaxis on incidence of febrile neutropenia in patients with early stage breast cancer.

Radiation-Induced Esophagitis: A Common, Debilitating Clinical Challenge in Thoracic Radiotherapy

Radiation-Induced Esophagitis: A Common, Debilitating Clinical Challenge in Thoracic Radiotherapy

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A review of current options and ongoing trials for managing ARIE, a common esophageal adverse effect caused by radiotherapy to the thoracic region for lung, breast, or head and neck cancers, or lymphoma.

Dexrazoxane May Reduce Cardiotoxicity in Pediatric AML

Dexrazoxane May Reduce Cardiotoxicity in Pediatric AML

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Children's Oncology Group study reported on the effect of dexrazoxane on cardiotoxicity of anthracycline-containing regimens in pediatric patients with AML at the 2018 ASCO Annual Meeting.

Walking Program Improved Physical Function, But Not Fatigue, After RT for Breast Cancer

Walking Program Improved Physical Function, But Not Fatigue, After RT for Breast Cancer

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In a multicenter phase 2 study, the Walk With Ease program was evaluated for its effectiveness in reducing radiotherapy-associated fatigue vs usual care in older patients with breast cancer. Results were presented at 2018 ASCO Annual Meeting.

Palliative Issues Inadequately Addressed Among Hospitalized Cancer Patients

Palliative Issues Inadequately Addressed Among Hospitalized Cancer Patients

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Consultations for palliative care for hospitalized highly symptomatic patients with cancer is low regardless of curability or whether patient has hematologic or solid cancer, a study presented at 2018 ASCO has shown.

Severe Folate Deficiency Associated With Olaparib for Relapsed Ovarian Cancer

Severe Folate Deficiency Associated With Olaparib for Relapsed Ovarian Cancer

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In a case study, olaparib was found to induce folate deficiency in most patients with relapsed ovarian cancer. Researchers discuss the significance of this adverse effect and how it was managed.

Radiotherapy-Induced Nausea, Vomiting Affect QOL for Patients, Caregivers Differently

Radiotherapy-Induced Nausea, Vomiting Affect QOL for Patients, Caregivers Differently

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Outcomes assessment of patients participating in several different trials quantified the effect of nausea and vomiting separately, and on both the patient and the caregiver.

Patient Advocacy, Questioning 'Status Quo,' Improves Safety in Ambulatory Infusion Setting

Patient Advocacy, Questioning 'Status Quo,' Improves Safety in Ambulatory Infusion Setting

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In fielding reports of CNS-related adverse effects from patients in the ambulatory infusion room, nurses were able to prompt a pharmacy practice review. The outcomes of the resulting switch in premedication for HSR was presented at the 2018 ONS Annual Congress.

NP-Led Clinics Improved Phase 1 Oncology Study Operations, Outcomes

NP-Led Clinics Improved Phase 1 Oncology Study Operations, Outcomes

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A clinic staffed with clinical research nurses provided needed care for patients in clinical trials who experienced adverse effects, and also ensured consistent documentation of treatment-related AEs, according to a presentation at the 2018 ONS Annual Congress.

Multimodal Follow-up Improved Postradiotherapy Sexual Health in Lower GI, Gynecologic Cancers

Multimodal Follow-up Improved Postradiotherapy Sexual Health in Lower GI, Gynecologic Cancers

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Researchers sought to determine the effectiveness of a multimodal continuity of care program for women receiving radiation therapy for gynecologic or lower GI cancers. Their findings were presented at the 2018 ONS Annual Congress.

Scalp Cooling With Dignicap May Reduce Alopecia During Chemotherapy for Breast Cancer

Scalp Cooling With Dignicap May Reduce Alopecia During Chemotherapy for Breast Cancer

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A study results presented at the 2018 ONS Annual Congress demonstrated that incorporating scalp cooling with the Dignicap device prior to chemotherapy for breast cancer may reduce treatment-related alopecia.

Low Level Laser Therapy May Prevent Oral Mucositis During HSCT Conditioning

Low Level Laser Therapy May Prevent Oral Mucositis During HSCT Conditioning

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Researchers assessed the effectiveness of low level laser therapy in preventing or minimizing oral mucositis in patients with hematologic cancers preparing to undergo HSCT. Results were presented at the 2018 ONS Annual Congress.

Electronic Self-Report Assessment-Cancer May Preserve Physical Function in Chemotherapy-Induced Peripheral Neuropathy

Electronic Self-Report Assessment-Cancer May Preserve Physical Function in Chemotherapy-Induced Peripheral Neuropathy

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Research presented at the 2018 ONS Congress reported on the effectiveness of ESRA-C, a web-based assessment and self-care intervention program, in the management of CIPN in patients receiving platinum and/or taxane-based chemotherapy.

Mitomycin Extravasation Protocol

Mitomycin Extravasation Protocol

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What is the protocol for extravasation of Mitomycin C?

Evidence-Based Practices, No CLABSIs Achieved Through Quality Improvement

Evidence-Based Practices, No CLABSIs Achieved Through Quality Improvement

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Faced with an increasing CLABSI rate on their oncology unit, nurse leaders at this rural Northwest hospital surveyed their staff to identify the changes they needed to make. Implementing those changes resulted in a dramatic improvement in patient care outcomes.

Moderately Emetogenic Chemotherapy Drug Demonstrates High Emetogenic Potential

Moderately Emetogenic Chemotherapy Drug Demonstrates High Emetogenic Potential

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Based on results of a prospective and retrospective study evaluating emetogenic potential of 50 chemotherapeutic regimens, researchers suggest changing the classification of irinotecan.

Hope, Optimism Reduce Psychological Distress in Advanced Cancer

Hope, Optimism Reduce Psychological Distress in Advanced Cancer

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A cross-sectional analysis evaluated the impact of hope and optimism on different facets of psychological distress among patients with advanced melanoma, colorectal, lung, or gastrointestinal cancers.

Intervention Improves Body Image-Related Distress in Survivors of Breast Cancer

Intervention Improves Body Image-Related Distress in Survivors of Breast Cancer

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A randomized study assessed the effectiveness of an Internet-based psychological intervention in helping women survivors of breast cancer cope with the changes brought by their disease and treatment.

Support for Exercise Programs During, After Cancer Treatment

Support for Exercise Programs During, After Cancer Treatment

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Which organizations recommend incorporating physical activity into cancer care and why?

Elevated Pre-HCT Iron Levels Predictive of Worse Survival Outcomes in AML/MDS

Elevated Pre-HCT Iron Levels Predictive of Worse Survival Outcomes in AML/MDS

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The ALLIVE trial sought to determine if eLPI levels were predictive of iron-related toxicity and mortality after HCT in patients with AML or MDS.

HMB/Arg/Gln Does Not Reduce Oral Mucositis Incidence in Head and Neck Cancer

HMB/Arg/Gln Does Not Reduce Oral Mucositis Incidence in Head and Neck Cancer

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In a phase 2 study, researchers sought to determine the effectiveness of adding HMB/Arg/Gln to cisplatin-based chemoradiotherapy for patients with head and cancers to prevent CRT-induced oral mucositis.

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