Lung Cancer-Specific Distress Screening Tool Not Needed But Has Potential Benefit

Lung Cancer-Specific Distress Screening Tool Not Needed But Has Potential Benefit

Using focus groups, researchers evaluated patient-reported psychosocial consequences of lung cancer to determine if a lung cancer-specific distress screening instrument would benefit these patients.

Managing Rasburicase-Induced Hemolytic Anemia in G6PD-Deficient Population

Managing Rasburicase-Induced Hemolytic Anemia in G6PD-Deficient Population

Clinicians report on the challenges of managing rasburicase-induced G6PD deficiency in patients undergoing treatment for tumor lysis syndrome.

G-CSF Support Increases Overall Survival, But Risk of Secondary Malignancies Also Higher

G-CSF Support Increases Overall Survival, But Risk of Secondary Malignancies Also Higher

A meta-analysis of 14 randomized, controlled trials was conducted to determine if combining G-CSF with intensified chemotherapy improved overall survival.

Report From Childhood Cancer Survivor Study Identifies Long-Term Risks for VTE

Report From Childhood Cancer Survivor Study Identifies Long-Term Risks for VTE

Assessment of long-term risks for VTE based on data from almost 30,000 childhood cancer survivors and siblings, with approximately 21 years of follow-up.

Clinical Characteristics That Increase Risk of Chemotherapy-Induced Febrile Neutropenia Identified

Clinical Characteristics That Increase Risk of Chemotherapy-Induced Febrile Neutropenia Identified

Researchers analyzed data from more than 15,000 patients in Southern California with various cancers to identify clinical factors that contribute to the risk of developing chemotherapy-induced febrile neutropenia.

Hodgkin Lymphoma Survivorship Marked by Periods of Actionable Distress

Hodgkin Lymphoma Survivorship Marked by Periods of Actionable Distress

A retrospective evaluation of patients treated at a tertiary cancer center demonstrated that patients with Hodgkin lymphoma experienced periods of actionable distress in survivorship, despite a low overall distress burden.

Commission Seeks Standardized Adverse Event Assessments in Hematologic Malignancies

Commission Seeks Standardized Adverse Event Assessments in Hematologic Malignancies

A snapshot of an international Commission's report on the issues inherent with adverse event reports of hematologic malingnancies in clinical trials.

Delirium Can Hinder Effectiveness of Palliative Care in Advanced Cancer

Delirium Can Hinder Effectiveness of Palliative Care in Advanced Cancer

A prospective analysis of patients with advanced cancer revealed the effect delirium has on palliative care and symptom management at baseline and after 7 days of treatment.

ASCO, SITC Release Recommendations for Clinical Trial Reporting of Immunotherapy Adverse Events

ASCO, SITC Release Recommendations for Clinical Trial Reporting of Immunotherapy Adverse Events

As immunotherapies gain a stronger foothold as a treatment option for cancer, ASCO and SITC convened a panel to develop recommendations to ensure consistent and efficient clinical trial reporting in immuno-oncology.

Chemotherapy Side Effects in Women vs Men: Broader Range, More Severe

Chemotherapy Side Effects in Women vs Men: Broader Range, More Severe

An analysis of pooled data from 4 randomized controlled clinical trials revealed that male and female patients experience different chemotherapy side effects and at different severities, according to a poster presented at ESMO 2018 Congress.

Prospective Study Measures Cognitive, Treatment Effects in Older Breast Cancer Survivors

Prospective Study Measures Cognitive, Treatment Effects in Older Breast Cancer Survivors

Thinking and Living With Cancer (TLC) sought to determine the effects of breast cancer treatment and age on cognitive function in older breast cancer survivors over time.

Immune Checkpoint Inhibitor Therapy May Affect Thyroid Function

Immune Checkpoint Inhibitor Therapy May Affect Thyroid Function

A review of medical records revealed that thyroid function may be affected by immune checkpoint inhibitor therapy, and these patients should undergo thyroid function tests, especially during the first 8 weeks of therapy.

Delayed Administration Device for Pegfilgratim Safe, Effective in Preventing Grade 4 Neutropenia

Delayed Administration Device for Pegfilgratim Safe, Effective in Preventing Grade 4 Neutropenia

In a comparison study, the Onpro® device was found to be a safe and effective alternative to manual injection of pegfilgrastim in patients receiving chemotherapy.

Self-Care Toolkits Ease Negative PostSurgery Experiences for Patients With Breast Cancer

Self-Care Toolkits Ease Negative PostSurgery Experiences for Patients With Breast Cancer

Self-care toolkits were found to reduce pain and other negative postsurgical experiences for women undergoing surgical procedures for breast cancer.

Influence of Surgical Options for Early-Stage Lung Cancer on Opioid Use

Influence of Surgical Options for Early-Stage Lung Cancer on Opioid Use

A research letter presents results of a study on opioid use among patients in the SEER database who underwent open resection vs VATS for non-small cell lung cancer.

Opioid Overdose Statistics Among Cancer Population Is Different From General Population

Opioid Overdose Statistics Among Cancer Population Is Different From General Population

Researchers sought to determine the incidence and demographic factors of patients with cancer whose deaths were attributed to opioid overdose over a 10-year period.

Nonopioid Pain Medications Found to Control Postop Pain, Reduce Anxiety Effectively

Nonopioid Pain Medications Found to Control Postop Pain, Reduce Anxiety Effectively

Researchers presented results of a project designed to reduce opioid use while effectively managing pain and anxiety in patients who had undergone surgery for urologic cancer at the 2018 ASCO Quality Care Symposium.

Infections in Primary Immune Thrombocytopenia Associated With Low Platelet Count

Infections in Primary Immune Thrombocytopenia Associated With Low Platelet Count

A retrospective study of platelet- and infection-related data from patients with ITP revealed the influence platelet levels have on infections as well as efficacy of transfusions.

Immune Checkpoint Inhibitors: A Review of Side Effects, Their Causes and Incidence

Immune Checkpoint Inhibitors: A Review of Side Effects, Their Causes and Incidence

A multicenter research team determined the incidence and type of fatal toxic effects associated with immune checkpoint inhibitors.

Estimating Quality of Life Based on Cumulative Drug Toxicity in Colorectal Cancer

Estimating Quality of Life Based on Cumulative Drug Toxicity in Colorectal Cancer

Results of a study in which more than 100 patients with metastatic colorectal cancer completed EORTC-QLQ-C30 suggests an association between assessment of cumulative drug toxicities and predictions of quality of life for patients undergoing first-line chemotherapy for the disease.

Nedaplatin vs Cisplatin for Malignancy-Induced MPE: Noninferior, Less Toxicity

Nedaplatin vs Cisplatin for Malignancy-Induced MPE: Noninferior, Less Toxicity

Researchers sought to determine if nedaplatin could effectively manage malignancy-induced MPE in patients with cancer with less toxicity than cisplatin.

Metronidazole, Vancomycin Recommended for C Difficile in Pediatric Oncology, HSCT

Metronidazole, Vancomycin Recommended for C Difficile in Pediatric Oncology, HSCT

An international multidisciplinary panel of experts in pediatric oncology and infectious diseases convened to develop recommendations for the prevention and treatment of C difficile infection in pediatric patients with cancer or who are undergoing HSCT.

Pulmonary Toxicity Increased in Pediatric Hodgkin Lymphoma Treated With Brentuximab Vedotin

Pulmonary Toxicity Increased in Pediatric Hodgkin Lymphoma Treated With Brentuximab Vedotin

A retrospective study evaluated the efficacy vs pulmonary toxicity of brentuximab vedotin for relapsed or refractory Hodgkin lymphoma in pediatric patients.

Late Lower Cranial Neuropathy Worsens Symptom Burden in Oropharyngeal Cancer Survivors

Late Lower Cranial Neuropathy Worsens Symptom Burden in Oropharyngeal Cancer Survivors

Researchers conducted a cross-sectional study to determine the incidence and effect of late lower cranial neuropathies on survivors of oropharyngeal cancers.

SD-101 May Enhance the Effectiveness of Immunotherapy in Melanoma

SD-101 May Enhance the Effectiveness of Immunotherapy in Melanoma

In this phase 1b study, researchers evaluated the efficacy of immunotherapy with pembrolizumab to treat advanced melanoma.

Pre-HSCT Conditioning May Improve Physical Functioning in Hematologic Cancers

Pre-HSCT Conditioning May Improve Physical Functioning in Hematologic Cancers

In this retrospective study, researchers assessed the outcomes of 88 patients with hematologic disease who underwent HSCT.

Nonmyeloablative/Reduced-Intensity Conditioning May Reduce Mucositis in HCT

Nonmyeloablative/Reduced-Intensity Conditioning May Reduce Mucositis in HCT

Researchers sought to determine if NMA or reduced-intensity conditioning with busulfan improved severity/duration of oral mucositis compared with myeloablative conditioning in patients with hematologic cancer undergoing HCT.

FDA, EU Approvals Sought for Split Dose Regimen of Daratumumab for Multiple Myeloma

FDA, EU Approvals Sought for Split Dose Regimen of Daratumumab for Multiple Myeloma

The manufacturer of daratumumab, a CD38-directed antibody for the treatment of multiple myeloma, has submitted a sBLA and a type II variation to the US FDA and European Medicines Agency, respectively, for approval of a split dosing regimen.

8 Hours of Bedrest May Be Ideal After Intrathecal Chemotherapy in Hematologic Cancers

8 Hours of Bedrest May Be Ideal After Intrathecal Chemotherapy in Hematologic Cancers

In an open-label study, researchers sought to determine the optimal amount of bed rest after intrathecal chemotherapy for patients with hematologic cancers.

Assessing Direct Costs of Treatment-Related Adverse Events in Advanced Melanoma

Assessing Direct Costs of Treatment-Related Adverse Events in Advanced Melanoma

In a systematic review, researchers explored the financial burden of treating grade 3 to 4 adverse events associated with melanoma and its treatment.

Healthcare Use, Economic Burden Greater With Cancer-Related Opioid-Induced Constipation

Healthcare Use, Economic Burden Greater With Cancer-Related Opioid-Induced Constipation

Use of opioids to manage cancer-related pain may have adverse effects of its own that can have a significant impact on healthcare use among patients with cancer.

Effect of HSCT on HRQOL and Posttraumatic Stress in Young Adult Cancer Survivors

Effect of HSCT on HRQOL and Posttraumatic Stress in Young Adult Cancer Survivors

Study sought to determine the health-related QOL and posttraumatic stress symptoms in adolescent and young adult cancer survivors post-HSCT compared with their healthy peers.

Propolis Mouthwash Treatment Effectively Eases Severe Oral Mucositis

Propolis Mouthwash Treatment Effectively Eases Severe Oral Mucositis

In this systematic review, investigators sought to determine the safety, effectiveness, and tolerability of propolis mouthwash in preventing severe oral mucositis in patients undergoing chemotherapy or radiotherapy.

Hypnosis: A Comparison of the Efficacy of an Intervention Across Patient Populations

Hypnosis: A Comparison of the Efficacy of an Intervention Across Patient Populations

Researchers sought to determine if men with prostate cancer would derive the same benefits from hypnosis as women with breast cancer. Their results highlight significant differences in what is helpful for men vs women.

Carfilzomib Benefits May Outweigh Cardiovascular Risk in Multiple Myeloma

Carfilzomib Benefits May Outweigh Cardiovascular Risk in Multiple Myeloma

In an analysis of 11 studies, researchers investigated whether the benefits of carfilzomib for multiple myeloma outweigh the cardiovascular risks. However, the researchers recommend careful monitoring and management of blood pressure and volume status as good clinical practice, regardless.

Genetic Link Between Depression and Breast Cancer Remains Unclear

Genetic Link Between Depression and Breast Cancer Remains Unclear

In this study, researchers sought to determine if a genetic predisposition to depression exists in some patients with breast cancer and how to identify it.

Staff Education Leads to Increase in Oncology Rehabilitation Referrals

Staff Education Leads to Increase in Oncology Rehabilitation Referrals

Educational intervention for oncology clinicians at a rural Michigan oncology clinic does not demonstrate a statistically significant increase in referrals to rehabilitation; however, results show a clinically significant improvement in identification of need, communication among staff, and potential for greater referrals.

Chinese Traditional Medicine Showed Effectiveness on Pain, Quality of Life in Advanced Cancer

Chinese Traditional Medicine Showed Effectiveness on Pain, Quality of Life in Advanced Cancer

In a randomized study, researchers sought to determine the effect of IV injections of coix seed oil, a Chinese CAM, on pain and quality of life measures for patients with advanced cancer.

Handgrip Force May Provide Objective Evaluation of Cancer-Related Fatigue

Handgrip Force May Provide Objective Evaluation of Cancer-Related Fatigue

Researchers sought to determine if handgrip force could provide objective measures of CRF in patients with cancer.

CALM: A Depression Intervention for Cancer Patients at the End of Life

CALM: A Depression Intervention for Cancer Patients at the End of Life

The effectiveness of a novel intervention intended to reduce and/or prevent depression in patients with advanced cancer at the end of life was investigated in a randomized study with more than 300 patients.

Live or Online Mindfulness-Based Cognitive Therapy Reduced Cancer-Related Psychological Distress

Live or Online Mindfulness-Based Cognitive Therapy Reduced Cancer-Related Psychological Distress

Mindfulness-based interventions are proven effective in helping patients with cancer manage distress and other psychological symptoms. In this study, researchers sought to determine if Internet-based MBCT can be as effective as face-to-face interventions.

PTSD May Increase Symptom Burden in Patients With Cancer

PTSD May Increase Symptom Burden in Patients With Cancer

Post-traumatic stress symptoms are linked to a greater symptom burden in hospitalized cancer patients.

Managing Dyspnea With Fentanyl in Patients With Cancer at End of Life

Managing Dyspnea With Fentanyl in Patients With Cancer at End of Life

In this retrospective study, researchers sought to determine the effectiveness of fentanyl for dyspnea in dying patients with advanced cancer.

Malnutrition, Decreased QOL Possible After Radiation Therapy for Head and Neck Cancer

Malnutrition, Decreased QOL Possible After Radiation Therapy for Head and Neck Cancer

In a retrospective study, researchers used established tools to measure the nutritional status of patients with head and neck cancer before, immediately after, and at 2 follow-up points after radiotherapy.

Ixazomib, Lenalidomide, Dexamethasone Effective But Increases Toxicity in Multiple Myeloma

Ixazomib, Lenalidomide, Dexamethasone Effective But Increases Toxicity in Multiple Myeloma

Three-drug regimen twice a week achieved good response and long-term outcomes in patients with newly diagnosed multiple myeloma; however, regimen has higher toxicity than once weekly dose.

Low-Dose Dasatinib for Chronic-Phase CML Safe, Effective With Fewer Adverse Events

Low-Dose Dasatinib for Chronic-Phase CML Safe, Effective With Fewer Adverse Events

In this study, researchers assigned 75 patients with newly diagnosed Philadelphia chromosome (Ph)-positive CML-CP to receive dasatinib 50 mg once daily.

Childhood Neuroblastoma Survivors at Risk for Psych Impairment

Childhood Neuroblastoma Survivors at Risk for Psych Impairment

Psychological impairment seen particularly in survivors with chronic health conditions.

Navigating the Benefits and Challenges of Immunotherapy

Navigating the Benefits and Challenges of Immunotherapy

A review of immunotherapy — what they are, how they work, and what to watch for — was presented at the 2018 ONA Navigation Summit.

Muscle Loss Not Always Correlated With Loss of Function, Strength in Cancer Cachexia

Muscle Loss Not Always Correlated With Loss of Function, Strength in Cancer Cachexia

Interventions specifically designed to target cachexia in patients with thoracic or gastrointestinal cancer and established cachexia were effective in helping patients preserve functional stability and rehabilitation potential.

Association Between Multiple Myeloma With VTE and Increased Mortality at 2, 5 Years

Association Between Multiple Myeloma With VTE and Increased Mortality at 2, 5 Years

A study presented at the 2018 ASCO Annual Meeting investigated the mortality risk for patients with multiple myeloma who develop VTE.

Primary Prophylaxis Key in Reducing Febrile Neutropenia in Early Breast Cancer

Primary Prophylaxis Key in Reducing Febrile Neutropenia in Early Breast Cancer

In a retrospective study, researchers investigated the effect of primary prophylaxis on incidence of febrile neutropenia in patients with early stage breast cancer.

Radiation-Induced Esophagitis: A Common, Debilitating Clinical Challenge in Thoracic Radiotherapy

Radiation-Induced Esophagitis: A Common, Debilitating Clinical Challenge in Thoracic Radiotherapy

A review of current options and ongoing trials for managing ARIE, a common esophageal adverse effect caused by radiotherapy to the thoracic region for lung, breast, or head and neck cancers, or lymphoma.

Head and Neck Cancer Survival Improved When irAEs Occur During Anti-PD-1 Therapy

Head and Neck Cancer Survival Improved When irAEs Occur During Anti-PD-1 Therapy

Researchers evaluated whether the development of irAEsc among patients with metastatic head and neck cancer who have failed platinum-based chemotherapy could improve patient outcomes.

Palliative Issues Inadequately Addressed Among Hospitalized Cancer Patients

Palliative Issues Inadequately Addressed Among Hospitalized Cancer Patients

Consultations for palliative care for hospitalized highly symptomatic patients with cancer is low regardless of curability or whether patient has hematologic or solid cancer, a study presented at 2018 ASCO has shown.

Severe Folate Deficiency Associated With Olaparib for Relapsed Ovarian Cancer

Severe Folate Deficiency Associated With Olaparib for Relapsed Ovarian Cancer

In a case study, olaparib was found to induce folate deficiency in most patients with relapsed ovarian cancer. Researchers discuss the significance of this adverse effect and how it was managed.

Radiotherapy-Induced Nausea, Vomiting Affect QOL for Patients, Caregivers Differently

Radiotherapy-Induced Nausea, Vomiting Affect QOL for Patients, Caregivers Differently

Outcomes assessment of patients participating in several different trials quantified the effect of nausea and vomiting separately, and on both the patient and the caregiver.

Patient Advocacy, Questioning 'Status Quo,' Improves Safety in Ambulatory Infusion Setting

Patient Advocacy, Questioning 'Status Quo,' Improves Safety in Ambulatory Infusion Setting

In fielding reports of CNS-related adverse effects from patients in the ambulatory infusion room, nurses were able to prompt a pharmacy practice review. The outcomes of the resulting switch in premedication for HSR was presented at the 2018 ONS Annual Congress.

Peripheral Neuropathy Frequent for Childhood Cancer Survivors

Peripheral Neuropathy Frequent for Childhood Cancer Survivors

Long-term neurotoxicity was more frequently seen with cisplatin than with vinca alkaloids, data indicates.

NP-Led Clinics Improved Phase 1 Oncology Study Operations, Outcomes

NP-Led Clinics Improved Phase 1 Oncology Study Operations, Outcomes

A clinic staffed with clinical research nurses provided needed care for patients in clinical trials who experienced adverse effects, and also ensured consistent documentation of treatment-related AEs, according to a presentation at the 2018 ONS Annual Congress.

Simple Adjustment Key to Paclitaxel Infusion Protocol That Reduced Hypersensitivity Reactions

Simple Adjustment Key to Paclitaxel Infusion Protocol That Reduced Hypersensitivity Reactions

A project presented at the 2018 ONS Annual Congress demonstrated the effectiveness of standardizing nursing practices for paclitaxel infusions.

Low Level Laser Therapy May Prevent Oral Mucositis During HSCT Conditioning

Low Level Laser Therapy May Prevent Oral Mucositis During HSCT Conditioning

Researchers assessed the effectiveness of low level laser therapy in preventing or minimizing oral mucositis in patients with hematologic cancers preparing to undergo HSCT. Results were presented at the 2018 ONS Annual Congress.

Oncology Extended Care Clinic Reduced Urgent Cancer-Related ED Visits

Oncology Extended Care Clinic Reduced Urgent Cancer-Related ED Visits

Oncology extended care clinics were shown to significantly improve urgent care needs of patients with cancer without unnecessarily burdening the ED or compromising patient care, according to a presentation at the 2018 ONS Annual Congress.

Posttreatment Visual Function, Ocular Symptoms Impact QOL in Head and Neck Cancer

Posttreatment Visual Function, Ocular Symptoms Impact QOL in Head and Neck Cancer

A link between visual function, ocular symptoms, and quality of life was found in cross-sectional study of patients who underwent radiotherapy for head and neck cancers, according to a presentation at the 2018 ONS Annual Congress.

Electronic Self-Report Assessment-Cancer May Preserve Physical Function in Chemotherapy-Induced Peripheral Neuropathy

Electronic Self-Report Assessment-Cancer May Preserve Physical Function in Chemotherapy-Induced Peripheral Neuropathy

Research presented at the 2018 ONS Congress reported on the effectiveness of ESRA-C, a web-based assessment and self-care intervention program, in the management of CIPN in patients receiving platinum and/or taxane-based chemotherapy.

Can a Smartphone App Track Patient Symptoms During Clinical Trials?

Can a Smartphone App Track Patient Symptoms During Clinical Trials?

Researchers explored the effectiveness of using a smartphone app to monitor adverse effects of patients with cancer undergoing treatment as part of a clinical trial.

Evidence-Based Practices, No CLABSIs Achieved Through Quality Improvement

Evidence-Based Practices, No CLABSIs Achieved Through Quality Improvement

Faced with an increasing CLABSI rate on their oncology unit, nurse leaders at this rural Northwest hospital surveyed their staff to identify the changes they needed to make. Implementing those changes resulted in a dramatic improvement in patient care outcomes.

Moderately Emetogenic Chemotherapy Drug Demonstrates High Emetogenic Potential

Moderately Emetogenic Chemotherapy Drug Demonstrates High Emetogenic Potential

Based on results of a prospective and retrospective study evaluating emetogenic potential of 50 chemotherapeutic regimens, researchers suggest changing the classification of irinotecan.

Hope, Optimism Reduce Psychological Distress in Advanced Cancer

Hope, Optimism Reduce Psychological Distress in Advanced Cancer

A cross-sectional analysis evaluated the impact of hope and optimism on different facets of psychological distress among patients with advanced melanoma, colorectal, lung, or gastrointestinal cancers.

Intervention Improves Body Image-Related Distress in Survivors of Breast Cancer

Intervention Improves Body Image-Related Distress in Survivors of Breast Cancer

A randomized study assessed the effectiveness of an Internet-based psychological intervention in helping women survivors of breast cancer cope with the changes brought by their disease and treatment.

HMB/Arg/Gln Does Not Reduce Oral Mucositis Incidence in Head and Neck Cancer

HMB/Arg/Gln Does Not Reduce Oral Mucositis Incidence in Head and Neck Cancer

In a phase 2 study, researchers sought to determine the effectiveness of adding HMB/Arg/Gln to cisplatin-based chemoradiotherapy for patients with head and cancers to prevent CRT-induced oral mucositis.

Olanzapine Use to Prevent Chemotherapy-Induced Nausea and Vomiting

Olanzapine Use to Prevent Chemotherapy-Induced Nausea and Vomiting

Why is the antipsychotic olanzapine (Zyprexa) being used to prevent nausea?

1-year Imatinib or Nilotinib Therapy Not Associated with Cardiotoxity in CML

1-year Imatinib or Nilotinib Therapy Not Associated with Cardiotoxity in CML

Although many TKIs have well-documented cardiotoxic effects, results of a single-center prospective study that assessed effects of 1 year of therapy with imatinib or nilotinib in patients with CML demonstrated safety and efficacy of the 2 agents in this population.

Palonosetron Noninferior to Ondansetron for Pediatric Chemotherapy-induced Vomiting

Palonosetron Noninferior to Ondansetron for Pediatric Chemotherapy-induced Vomiting

In a prospective study, researchers sought to determine the noninferiority of palonosetron to ondansetron in pediatric patients with cancer receiving moderate or high emetogenic chemotherapy.

Nabilone Improves Cancer-Associated Anorexia in Lung Cancer

Nabilone Improves Cancer-Associated Anorexia in Lung Cancer

Researchers assessed the efficacy of nabilone for improving symptoms of anorexia in patients with NSCLC. In addition, patient appetite, quality of life, and nutritional status were also assessed.

Androgen-Deprivation Therapy for Prostate Cancer May Cause Nocturia, Sleep Disturbance

Androgen-Deprivation Therapy for Prostate Cancer May Cause Nocturia, Sleep Disturbance

ADT recipients reported worse subjective sleep disturbance, researchers found.

CHEMO-SUPPORT: A Nursing Intervention to Relieve Chemotherapy Symptom Burden

CHEMO-SUPPORT: A Nursing Intervention to Relieve Chemotherapy Symptom Burden

Results of a mixed-method study that used a combination of self-report tools evaluated the efficacy of CHEMO-SUPPORT, a patient support program designed to help patients manage their chemotherapy-related symptoms at home.

Approach and Management of Checkpoint Inhibitor-related Immune Hepatitis

Approach and Management of Checkpoint Inhibitor-related Immune Hepatitis

[Journal of Gastrointestinal Oncology] A review of diagnostic parameters and management modalities for checkpoint inhibitor-induced hepatic toxicity is presented.

Intervention Improves Breast Cancer Survivors' Memory Contentment

Intervention Improves Breast Cancer Survivors' Memory Contentment

Results of a prospective study demonstrated the effectiveness of a 1-hour psychoeducational intervention designed to help survivors of breast cancer manage their chemotherapy-related cognitive dysfunction and improve their memory contentment.

Advances in Prevention, Treatment of RT-Associated Radiodermatitis Hold Promise

Advances in Prevention, Treatment of RT-Associated Radiodermatitis Hold Promise

This review of radiodermatitis, a common adverse effect of radiation therapy, discusses preventive and treatment options available that reduce and/or minimize symptoms of the condition.

Calcitriol May Improve Hormone-Therapy Induced Osteoporosis in Breast Cancer Survivors

Calcitriol May Improve Hormone-Therapy Induced Osteoporosis in Breast Cancer Survivors

In this study, researchers determined the efficacy of calcitriol, weight-bearing exercise, both, or daily multivitamins on bone formation and resorption in breast cancer survivors actively maintained on hormone therapy.

Zinc Sulfate Improves Chemotherapy-Induced Mucositis Outcomes in Leukemia

Zinc Sulfate Improves Chemotherapy-Induced Mucositis Outcomes in Leukemia

Results of a triple-blind study demonstrate effectiveness of zinc sulfate in preventing chemotherapy-induced mucositis or reducing its incidence and severity in patients with leukemia receiving chemotherapy.

Cisplatin-Induced Adverse Events in Osteosarcoma Not Improved With Pantoprazole

Cisplatin-Induced Adverse Events in Osteosarcoma Not Improved With Pantoprazole

This phase 2 study sought to determine whether concurrent pantoprazole would improve cisplatin-induced ototoxicity and nephrotoxicity in younger patients with osteosarcoma.

Cachexia Not Improved With Celecoxib Plus Megestrol vs Megestrol Alone

Cachexia Not Improved With Celecoxib Plus Megestrol vs Megestrol Alone

Double-blind phase 3 study evaluated the effect of megestrol combined with celecoxib vs monotherapy on cachexia in patients with gastrointestinal cancer.

Chemotherapy-Related Fatigue Linked to Levothyroxine Use in Breast Cancer

Chemotherapy-Related Fatigue Linked to Levothyroxine Use in Breast Cancer

In a secondary analysis of the BEATE and INVEST study, researchers followed a link between levothyroxine use, exercise, and fatigue in women with breast cancer undergoing chemotherapy.

Self-guided Cognitive Behavioral Pain Management Shows Efficacy in Painful CIPN

Self-guided Cognitive Behavioral Pain Management Shows Efficacy in Painful CIPN

Self-guided online cognitive behavioral pain management may result in improved "worst" pain but not "average" pain compared with usual care for the treatment of painful chemotherapy-induced peripheral neuropathy.

Cardiotoxicity Risk Greater in Blacks With Breast Cancer Receiving HER2 Therapies

Cardiotoxicity Risk Greater in Blacks With Breast Cancer Receiving HER2 Therapies

Retrospective study examines the association between risk of cardiotoxicity and race in women with breast cancer receiving chemotherapy and at least 1 year of HER2-targeted therapy.

Prevention, Management of Hand-Foot Syndrome With Cooling Therapy

Prevention, Management of Hand-Foot Syndrome With Cooling Therapy

Researchers explored the effectiveness of wearing frozen gloves and socks before and after treatment with PLD to prevent or manage hand-foot syndrome in patients with ovarian cancer.

Chemotherapy Toxicity Risk Score Use Improved Treatment Choice for Elderly

Chemotherapy Toxicity Risk Score Use Improved Treatment Choice for Elderly

This observational study demonstrates the significance of using the chemotherapy toxicity risk score (CTRS) to determine if an elderly patient can safely tolerate standard-dose combination chemotherapy, or would fare better with a reduced-dose regimen.

Acupuncture Benefits Aromatase Inhibitor-Related Joint Pain

Acupuncture Benefits Aromatase Inhibitor-Related Joint Pain

Acupuncture may represent an effective adjuvant therapy in the management of joint pain associated with aromatase inhibitor treatment in postmenopausal women with breast cancer.

Resolving Vaginal Dryness in Women With a History of Breast Cancer

Resolving Vaginal Dryness in Women With a History of Breast Cancer

What are some nonhormonal treatments that can improve vaginal dryness in women with a history of breast cancer?

FDA Issues Warning for Rolapitant Injectable Emulsion in the Treatment of CINV

FDA Issues Warning for Rolapitant Injectable Emulsion in the Treatment of CINV

FDA issues black box warning for rolapitant regarding the potential for anaphylaxis, anaphylactic shock, and other hypersensitivity reactions in patients receiving the injectable emulsion for CINV prophylaxis.

Risk Factors for Arterial, Venous Thrombosis Differ in Polycythemia Vera

Risk Factors for Arterial, Venous Thrombosis Differ in Polycythemia Vera

Researchers assessed outcomes for 587 patients with PV to determine the risk factors most likely to predict arterial or venous thrombosis in this patient population.

Goshajinkigan May Not Prevent Chemotherapy-induced Peripheral Neuropathy in Cancer

Goshajinkigan May Not Prevent Chemotherapy-induced Peripheral Neuropathy in Cancer

Evidence from previous studies for patients with ovarian and endometrial cancers has suggested that goshajinkigan may treat and prevent CIPN.

Sarcopenia Severity Prognostic of Postchemotherapy Outcomes in the Elderly

Sarcopenia Severity Prognostic of Postchemotherapy Outcomes in the Elderly

Using a series of functional tests, researchers determined the significance of sarcopenia severity after chemotherapy in older patients with cancer and its effect on their physical independence.

Hearing Loss, Tinnitus May Predict Worse Outcomes for Cancer Survivors

Hearing Loss, Tinnitus May Predict Worse Outcomes for Cancer Survivors

A survey of 754 cancer survivors sought to determine the association between number of neurotoxicities such as CIN, hearing loss, and tinnitus and outcomes for these patients.

Exercise Reduces Severity of Chemotherapy-Induced Peripheral Neuropathy

Exercise Reduces Severity of Chemotherapy-Induced Peripheral Neuropathy

For this study, researchers sought to determine the effect exercise would have on severity of symptoms for patients who develop CIPN after taxane, platinum, or vinca alkaloid based chemotherapy.

Survey Reveals Opinions, Barriers Regarding Medical Marijuana Use in Children

Survey Reveals Opinions, Barriers Regarding Medical Marijuana Use in Children

A survey of pediatric oncology providers including physicians, nurses, and social workers reveals their willingness to consider medical marijuana for children with cancer, as well as their reasons against its use in these patients.

Aspirin Does Not Reduce Risk of Venous Thromboembolism in Multiple Myeloma

Aspirin Does Not Reduce Risk of Venous Thromboembolism in Multiple Myeloma

A retrospective study, presented at ASH 2017, determined the effectiveness of aspirin in reducing risk of VTE in patients with multiple myeloma at high risk of developing VTE.

Relapsed Ph-Negative Acute Lymphoblastic Leukemia Incurs a High Economic Burden

Relapsed Ph-Negative Acute Lymphoblastic Leukemia Incurs a High Economic Burden

Recent study findings investigated the economic burden of patients with relapsed Ph-negative ALL, and the adverse events of special interest that are most likely to have the greatest impact. These findings were presented at ASH 2017.

Sign Up for Free e-newsletters



Regimen and Drug Listings

GET FULL LISTINGS OF TREATMENT Regimens and Drug INFORMATION

Bone Cancer Regimens Drugs
Brain Cancer Regimens Drugs
Breast Cancer Regimens Drugs
Endocrine Cancer Regimens Drugs
Gastrointestinal Cancer Regimens Drugs
Genitourinary Cancer Regimens Drugs
Gynecologic Cancer Regimens Drugs
Head and Neck Cancer Regimens Drugs
Hematologic Cancer Regimens Drugs
Lung Cancer Regimens Drugs
Other Cancers Regimens
Rare Cancers Regimens
Skin Cancer Regimens Drugs