Using focus groups, researchers evaluated patient-reported psychosocial consequences of lung cancer to determine if a lung cancer-specific distress screening instrument would benefit these patients.
Clinicians report on the challenges of managing rasburicase-induced G6PD deficiency in patients undergoing treatment for tumor lysis syndrome.
A meta-analysis of 14 randomized, controlled trials was conducted to determine if combining G-CSF with intensified chemotherapy improved overall survival.
Assessment of long-term risks for VTE based on data from almost 30,000 childhood cancer survivors and siblings, with approximately 21 years of follow-up.
Researchers analyzed data from more than 15,000 patients in Southern California with various cancers to identify clinical factors that contribute to the risk of developing chemotherapy-induced febrile neutropenia.
A retrospective evaluation of patients treated at a tertiary cancer center demonstrated that patients with Hodgkin lymphoma experienced periods of actionable distress in survivorship, despite a low overall distress burden.
A snapshot of an international Commission's report on the issues inherent with adverse event reports of hematologic malingnancies in clinical trials.
A prospective analysis of patients with advanced cancer revealed the effect delirium has on palliative care and symptom management at baseline and after 7 days of treatment.
As immunotherapies gain a stronger foothold as a treatment option for cancer, ASCO and SITC convened a panel to develop recommendations to ensure consistent and efficient clinical trial reporting in immuno-oncology.
An analysis of pooled data from 4 randomized controlled clinical trials revealed that male and female patients experience different chemotherapy side effects and at different severities, according to a poster presented at ESMO 2018 Congress.
Thinking and Living With Cancer (TLC) sought to determine the effects of breast cancer treatment and age on cognitive function in older breast cancer survivors over time.
A review of medical records revealed that thyroid function may be affected by immune checkpoint inhibitor therapy, and these patients should undergo thyroid function tests, especially during the first 8 weeks of therapy.
In a comparison study, the Onpro® device was found to be a safe and effective alternative to manual injection of pegfilgrastim in patients receiving chemotherapy.
Self-care toolkits were found to reduce pain and other negative postsurgical experiences for women undergoing surgical procedures for breast cancer.
A research letter presents results of a study on opioid use among patients in the SEER database who underwent open resection vs VATS for non-small cell lung cancer.
Researchers sought to determine the incidence and demographic factors of patients with cancer whose deaths were attributed to opioid overdose over a 10-year period.
Researchers presented results of a project designed to reduce opioid use while effectively managing pain and anxiety in patients who had undergone surgery for urologic cancer at the 2018 ASCO Quality Care Symposium.
A retrospective study of platelet- and infection-related data from patients with ITP revealed the influence platelet levels have on infections as well as efficacy of transfusions.
A multicenter research team determined the incidence and type of fatal toxic effects associated with immune checkpoint inhibitors.
Results of a study in which more than 100 patients with metastatic colorectal cancer completed EORTC-QLQ-C30 suggests an association between assessment of cumulative drug toxicities and predictions of quality of life for patients undergoing first-line chemotherapy for the disease.
Researchers sought to determine if nedaplatin could effectively manage malignancy-induced MPE in patients with cancer with less toxicity than cisplatin.
An international multidisciplinary panel of experts in pediatric oncology and infectious diseases convened to develop recommendations for the prevention and treatment of C difficile infection in pediatric patients with cancer or who are undergoing HSCT.
A retrospective study evaluated the efficacy vs pulmonary toxicity of brentuximab vedotin for relapsed or refractory Hodgkin lymphoma in pediatric patients.
Researchers conducted a cross-sectional study to determine the incidence and effect of late lower cranial neuropathies on survivors of oropharyngeal cancers.
In this phase 1b study, researchers evaluated the efficacy of immunotherapy with pembrolizumab to treat advanced melanoma.
In this retrospective study, researchers assessed the outcomes of 88 patients with hematologic disease who underwent HSCT.
Researchers sought to determine if NMA or reduced-intensity conditioning with busulfan improved severity/duration of oral mucositis compared with myeloablative conditioning in patients with hematologic cancer undergoing HCT.
The manufacturer of daratumumab, a CD38-directed antibody for the treatment of multiple myeloma, has submitted a sBLA and a type II variation to the US FDA and European Medicines Agency, respectively, for approval of a split dosing regimen.
In an open-label study, researchers sought to determine the optimal amount of bed rest after intrathecal chemotherapy for patients with hematologic cancers.
In a systematic review, researchers explored the financial burden of treating grade 3 to 4 adverse events associated with melanoma and its treatment.
Use of opioids to manage cancer-related pain may have adverse effects of its own that can have a significant impact on healthcare use among patients with cancer.
Study sought to determine the health-related QOL and posttraumatic stress symptoms in adolescent and young adult cancer survivors post-HSCT compared with their healthy peers.
In this systematic review, investigators sought to determine the safety, effectiveness, and tolerability of propolis mouthwash in preventing severe oral mucositis in patients undergoing chemotherapy or radiotherapy.
Researchers sought to determine if men with prostate cancer would derive the same benefits from hypnosis as women with breast cancer. Their results highlight significant differences in what is helpful for men vs women.
In an analysis of 11 studies, researchers investigated whether the benefits of carfilzomib for multiple myeloma outweigh the cardiovascular risks. However, the researchers recommend careful monitoring and management of blood pressure and volume status as good clinical practice, regardless.
In this study, researchers sought to determine if a genetic predisposition to depression exists in some patients with breast cancer and how to identify it.
Educational intervention for oncology clinicians at a rural Michigan oncology clinic does not demonstrate a statistically significant increase in referrals to rehabilitation; however, results show a clinically significant improvement in identification of need, communication among staff, and potential for greater referrals.
In a randomized study, researchers sought to determine the effect of IV injections of coix seed oil, a Chinese CAM, on pain and quality of life measures for patients with advanced cancer.
Researchers sought to determine if handgrip force could provide objective measures of CRF in patients with cancer.
The effectiveness of a novel intervention intended to reduce and/or prevent depression in patients with advanced cancer at the end of life was investigated in a randomized study with more than 300 patients.
Mindfulness-based interventions are proven effective in helping patients with cancer manage distress and other psychological symptoms. In this study, researchers sought to determine if Internet-based MBCT can be as effective as face-to-face interventions.
Post-traumatic stress symptoms are linked to a greater symptom burden in hospitalized cancer patients.
In this retrospective study, researchers sought to determine the effectiveness of fentanyl for dyspnea in dying patients with advanced cancer.
In a retrospective study, researchers used established tools to measure the nutritional status of patients with head and neck cancer before, immediately after, and at 2 follow-up points after radiotherapy.
Three-drug regimen twice a week achieved good response and long-term outcomes in patients with newly diagnosed multiple myeloma; however, regimen has higher toxicity than once weekly dose.
In this study, researchers assigned 75 patients with newly diagnosed Philadelphia chromosome (Ph)-positive CML-CP to receive dasatinib 50 mg once daily.
Psychological impairment seen particularly in survivors with chronic health conditions.
A review of immunotherapy — what they are, how they work, and what to watch for — was presented at the 2018 ONA Navigation Summit.
Interventions specifically designed to target cachexia in patients with thoracic or gastrointestinal cancer and established cachexia were effective in helping patients preserve functional stability and rehabilitation potential.
A study presented at the 2018 ASCO Annual Meeting investigated the mortality risk for patients with multiple myeloma who develop VTE.
In a retrospective study, researchers investigated the effect of primary prophylaxis on incidence of febrile neutropenia in patients with early stage breast cancer.
A review of current options and ongoing trials for managing ARIE, a common esophageal adverse effect caused by radiotherapy to the thoracic region for lung, breast, or head and neck cancers, or lymphoma.
Researchers evaluated whether the development of irAEsc among patients with metastatic head and neck cancer who have failed platinum-based chemotherapy could improve patient outcomes.
Consultations for palliative care for hospitalized highly symptomatic patients with cancer is low regardless of curability or whether patient has hematologic or solid cancer, a study presented at 2018 ASCO has shown.
In a case study, olaparib was found to induce folate deficiency in most patients with relapsed ovarian cancer. Researchers discuss the significance of this adverse effect and how it was managed.
Outcomes assessment of patients participating in several different trials quantified the effect of nausea and vomiting separately, and on both the patient and the caregiver.
In fielding reports of CNS-related adverse effects from patients in the ambulatory infusion room, nurses were able to prompt a pharmacy practice review. The outcomes of the resulting switch in premedication for HSR was presented at the 2018 ONS Annual Congress.
Long-term neurotoxicity was more frequently seen with cisplatin than with vinca alkaloids, data indicates.
A clinic staffed with clinical research nurses provided needed care for patients in clinical trials who experienced adverse effects, and also ensured consistent documentation of treatment-related AEs, according to a presentation at the 2018 ONS Annual Congress.
A project presented at the 2018 ONS Annual Congress demonstrated the effectiveness of standardizing nursing practices for paclitaxel infusions.
Researchers assessed the effectiveness of low level laser therapy in preventing or minimizing oral mucositis in patients with hematologic cancers preparing to undergo HSCT. Results were presented at the 2018 ONS Annual Congress.
Oncology extended care clinics were shown to significantly improve urgent care needs of patients with cancer without unnecessarily burdening the ED or compromising patient care, according to a presentation at the 2018 ONS Annual Congress.
A link between visual function, ocular symptoms, and quality of life was found in cross-sectional study of patients who underwent radiotherapy for head and neck cancers, according to a presentation at the 2018 ONS Annual Congress.
Electronic Self-Report Assessment-Cancer May Preserve Physical Function in Chemotherapy-Induced Peripheral Neuropathy
Research presented at the 2018 ONS Congress reported on the effectiveness of ESRA-C, a web-based assessment and self-care intervention program, in the management of CIPN in patients receiving platinum and/or taxane-based chemotherapy.
Researchers explored the effectiveness of using a smartphone app to monitor adverse effects of patients with cancer undergoing treatment as part of a clinical trial.
Faced with an increasing CLABSI rate on their oncology unit, nurse leaders at this rural Northwest hospital surveyed their staff to identify the changes they needed to make. Implementing those changes resulted in a dramatic improvement in patient care outcomes.
Based on results of a prospective and retrospective study evaluating emetogenic potential of 50 chemotherapeutic regimens, researchers suggest changing the classification of irinotecan.
A cross-sectional analysis evaluated the impact of hope and optimism on different facets of psychological distress among patients with advanced melanoma, colorectal, lung, or gastrointestinal cancers.
A randomized study assessed the effectiveness of an Internet-based psychological intervention in helping women survivors of breast cancer cope with the changes brought by their disease and treatment.
In a phase 2 study, researchers sought to determine the effectiveness of adding HMB/Arg/Gln to cisplatin-based chemoradiotherapy for patients with head and cancers to prevent CRT-induced oral mucositis.
Why is the antipsychotic olanzapine (Zyprexa) being used to prevent nausea?
Although many TKIs have well-documented cardiotoxic effects, results of a single-center prospective study that assessed effects of 1 year of therapy with imatinib or nilotinib in patients with CML demonstrated safety and efficacy of the 2 agents in this population.
In a prospective study, researchers sought to determine the noninferiority of palonosetron to ondansetron in pediatric patients with cancer receiving moderate or high emetogenic chemotherapy.
Researchers assessed the efficacy of nabilone for improving symptoms of anorexia in patients with NSCLC. In addition, patient appetite, quality of life, and nutritional status were also assessed.
ADT recipients reported worse subjective sleep disturbance, researchers found.
Results of a mixed-method study that used a combination of self-report tools evaluated the efficacy of CHEMO-SUPPORT, a patient support program designed to help patients manage their chemotherapy-related symptoms at home.
[Journal of Gastrointestinal Oncology] A review of diagnostic parameters and management modalities for checkpoint inhibitor-induced hepatic toxicity is presented.
Results of a prospective study demonstrated the effectiveness of a 1-hour psychoeducational intervention designed to help survivors of breast cancer manage their chemotherapy-related cognitive dysfunction and improve their memory contentment.
This review of radiodermatitis, a common adverse effect of radiation therapy, discusses preventive and treatment options available that reduce and/or minimize symptoms of the condition.
In this study, researchers determined the efficacy of calcitriol, weight-bearing exercise, both, or daily multivitamins on bone formation and resorption in breast cancer survivors actively maintained on hormone therapy.
Results of a triple-blind study demonstrate effectiveness of zinc sulfate in preventing chemotherapy-induced mucositis or reducing its incidence and severity in patients with leukemia receiving chemotherapy.
This phase 2 study sought to determine whether concurrent pantoprazole would improve cisplatin-induced ototoxicity and nephrotoxicity in younger patients with osteosarcoma.
Double-blind phase 3 study evaluated the effect of megestrol combined with celecoxib vs monotherapy on cachexia in patients with gastrointestinal cancer.
In a secondary analysis of the BEATE and INVEST study, researchers followed a link between levothyroxine use, exercise, and fatigue in women with breast cancer undergoing chemotherapy.
Self-guided online cognitive behavioral pain management may result in improved "worst" pain but not "average" pain compared with usual care for the treatment of painful chemotherapy-induced peripheral neuropathy.
Retrospective study examines the association between risk of cardiotoxicity and race in women with breast cancer receiving chemotherapy and at least 1 year of HER2-targeted therapy.
Researchers explored the effectiveness of wearing frozen gloves and socks before and after treatment with PLD to prevent or manage hand-foot syndrome in patients with ovarian cancer.
This observational study demonstrates the significance of using the chemotherapy toxicity risk score (CTRS) to determine if an elderly patient can safely tolerate standard-dose combination chemotherapy, or would fare better with a reduced-dose regimen.
Acupuncture may represent an effective adjuvant therapy in the management of joint pain associated with aromatase inhibitor treatment in postmenopausal women with breast cancer.
What are some nonhormonal treatments that can improve vaginal dryness in women with a history of breast cancer?
FDA issues black box warning for rolapitant regarding the potential for anaphylaxis, anaphylactic shock, and other hypersensitivity reactions in patients receiving the injectable emulsion for CINV prophylaxis.
Researchers assessed outcomes for 587 patients with PV to determine the risk factors most likely to predict arterial or venous thrombosis in this patient population.
Evidence from previous studies for patients with ovarian and endometrial cancers has suggested that goshajinkigan may treat and prevent CIPN.
Using a series of functional tests, researchers determined the significance of sarcopenia severity after chemotherapy in older patients with cancer and its effect on their physical independence.
A survey of 754 cancer survivors sought to determine the association between number of neurotoxicities such as CIN, hearing loss, and tinnitus and outcomes for these patients.
For this study, researchers sought to determine the effect exercise would have on severity of symptoms for patients who develop CIPN after taxane, platinum, or vinca alkaloid based chemotherapy.
A survey of pediatric oncology providers including physicians, nurses, and social workers reveals their willingness to consider medical marijuana for children with cancer, as well as their reasons against its use in these patients.
A retrospective study, presented at ASH 2017, determined the effectiveness of aspirin in reducing risk of VTE in patients with multiple myeloma at high risk of developing VTE.
Recent study findings investigated the economic burden of patients with relapsed Ph-negative ALL, and the adverse events of special interest that are most likely to have the greatest impact. These findings were presented at ASH 2017.
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- Cancer Treatment and Research: What Lies Ahead in 2019
- Helping Patients Face the Challenge of Eating Healthy During Cancer Treatment
- Regular Physical Activity — Even Initiated Postdiagnosis — Improves Survival for Cancer Patients
- Continuous Therapy May Be Beneficial in Patients With Newly Diagnosed Multiple Myeloma
- Gastrointestinal Perforation Complicates Management of Mantle Cell Lymphoma
- Brain Exercise Program Eases Chemobrain in Breast Cancer Survivors
- Hormone Therapy for Breast Cancer (Fact Sheet)
- Counseling on the Dangers of Vaping
- Radical Prostatectomy vs Active Surveillance: Results of Nearly 3 Decades of Follow-up
- Potential of Fecal Microbiota Transplantation in Managing Immunotherapy-Associated Colitis
- Ixazomib Maintenance After ASCT Improves Progression-Free, Overall Survival in Multiple Myeloma
- Evolutionary Role of Chemotherapy in Advanced Nasopharyngeal Carcinoma: A Literature-based Network Meta-analysis
- Helping Patients Face the Challenge of Eating Healthy During Cancer Treatment
- Gastrointestinal Perforation Complicates Management of Mantle Cell Lymphoma
- Modernizing Eligibility Criteria Could Increase Access to, Participation in Clinical Trials
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