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Elderly Patients Are Underrepresented in Trials For Soft Tissue Sarcoma

Elderly Patients Are Underrepresented in Trials For Soft Tissue Sarcoma

With median age of participants in clinical trials for soft-tissue sarcoma younger than most patients who develop the disease, these researchers sought to determine the prevalence of including persons older than 65 in clinical trials and the efficacy of first-line chemotherapy for STS in older patients.

Developments in the Management of Advanced Soft-tissue Sarcoma - Olaratumab in Context

Developments in the Management of Advanced Soft-tissue Sarcoma - Olaratumab in Context

[OncoTargets and Therapy] This review examines the rationale of olaratumab in the treatment of advanced soft-tissue sarcomas and its emerging role in clinical practice.

Exercise May Mitigate Cardiotoxicity Associated With Doxorubicin Treatment

Exercise May Mitigate Cardiotoxicity Associated With Doxorubicin Treatment

Researchers injected Ewing sarcoma cells into mice to determine the effects of exercise on doxorubicin efficacy and treatment-related cardiotoxicity.

Vitamin D Supplementation is Recommended for Use in Young Patients With Sarcoma

Vitamin D Supplementation is Recommended for Use in Young Patients With Sarcoma

Just over half of patients in a standard therapy group had normal bone mineral density after a mean follow-up of 6 years; this contrasted with 93% of patients in a vitamin D supplementation group.

Progression-Free, Overall Survival in Liposarcoma Improved With Eribulin vs Dacarbazine

Progression-Free, Overall Survival in Liposarcoma Improved With Eribulin vs Dacarbazine

Comparison study shows significantly improved overall survival and progression-free survival in patients with advanced LPS treated with eribulin vs dacarbazine.

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