Risk Factors

Red Hair Variants of <i>MC1R</i> Influence Melanoma Risk Differently in Men, Women

Red Hair Variants of MC1R Influence Melanoma Risk Differently in Men, Women

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Multivariate logistic regression analyses were utilized by researchers to evaluate the effect of MC1R and melanoma risk in men vs women.

Serum Albumin May Indicate Prognosis for Survival in Acute Myeloblastic Leukemia

Serum Albumin May Indicate Prognosis for Survival in Acute Myeloblastic Leukemia

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A single-center retrospective study assessed the effectiveness of serum albumin levels and BMI as prognostic measures in patients with AML.

Adhering to Cytoreductive Therapy Use May Improve Outcomes in Polycythemia Vera

Adhering to Cytoreductive Therapy Use May Improve Outcomes in Polycythemia Vera

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In a retrospective analysis, researchers sought to determine the use of cytoreductive therapies in patients with high-risk and low-risk PV.

Frequency of Tanning, Risk for Melanoma Higher in Gym Tanners

Frequency of Tanning, Risk for Melanoma Higher in Gym Tanners

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The use of tanning beds and/or booths and their availability in gyms may increase the frequency of indoor tanning for physically active adults, a combination that further exacerbates their risk for melanoma.

Metformin Use May Improve Survival Outcomes in Bladder Cancer

Metformin Use May Improve Survival Outcomes in Bladder Cancer

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A review and meta-analysis evaluated the association between metformin use and bladder cancer incidence and various prognostic measures, such as PFS and OS.

Do Sunless Tanners Have Fewer Skin Cancer Risk Behaviors?

Do Sunless Tanners Have Fewer Skin Cancer Risk Behaviors?

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A cross-sectional study investigated the other skin cancer prevention habits of people who use sunless tanning to reduce their UV exposure.

VIDA Findings Do Not Support Use of Vitamin D Supplements as Cancer Preventative

VIDA Findings Do Not Support Use of Vitamin D Supplements as Cancer Preventative

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A post-hoc analysis of the VIDA study sought to determine if vitamin D levels influence risk for cancer and/or cancer prevention.

Genetic Susceptibility to Pancreatic Cancer Linked to 6 Specific Gene Mutations

Genetic Susceptibility to Pancreatic Cancer Linked to 6 Specific Gene Mutations

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Investigators conducted a case-control study of 3030 pancreatic cancer patients in an attempt to confirm which genes might render patients susceptible to pancreatic cancer.

Carfilzomib Benefits May Outweigh Cardiovascular Risk in Multiple Myeloma

Carfilzomib Benefits May Outweigh Cardiovascular Risk in Multiple Myeloma

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In an analysis of 11 studies, researchers investigated whether the benefits of carfilzomib for multiple myeloma outweigh the cardiovascular risks. However, the researchers recommend careful monitoring and management of blood pressure and volume status as good clinical practice, regardless.

Guideline Recommendations Offer No OS Benefit for Younger Patients With Rectal Cancer

Guideline Recommendations Offer No OS Benefit for Younger Patients With Rectal Cancer

A retrospective review of data from the National Cancer Data Base demonstrated that trends in rectal cancer may follow a pattern similar to that of colon cancer.

Higher Cancer Rates Confirmed in Women With Dense Breasts

Higher Cancer Rates Confirmed in Women With Dense Breasts

Higher rate of recall, lower sensitivity, larger tumor diameter, and more lymph node-positive disease observed in women with dense breasts.

High BMI Among Premenopausal Women May Improve Risk for Breast Cancer

High BMI Among Premenopausal Women May Improve Risk for Breast Cancer

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Researchers report on a study to determine the relationship between BMI and risk for breast cancer among younger women, particularly those 18 to 24 years old.

Counseling Intervention That Improved CHD is Applied to Cancer Risk in Men

Counseling Intervention That Improved CHD is Applied to Cancer Risk in Men

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Researchers merged data from the Oslo diet and antismoking study with data from the Cancer Registry of Norway and the Norwegian Cause of Death Registry to determine if lifestyle changes that improved CHD rates in men would be as effective against cancer.

Factoring in Breast Density Improves Long-Term Risk Models for Breast Cancer

Factoring in Breast Density Improves Long-Term Risk Models for Breast Cancer

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A study using a cohort of women from Kaiser Permanente Washington evaluated the accuracy of risk assessment models for breast cancer that included classic risk factors with and without breast density as an additional factor during more than 10 years of follow-up.

Preoperative Aspirin Use May Not Increase Risk of Bleeding in Thyroid Surgery

Preoperative Aspirin Use May Not Increase Risk of Bleeding in Thyroid Surgery

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This study sought to determine if continuing preoperative aspirin therapy would increase the risk of bleeding complications in patients undergoing thyroid surgery.

Anticancer Properties of Omega-3 Fatty Acids: Plant-Based vs Marine-Based

Anticancer Properties of Omega-3 Fatty Acids: Plant-Based vs Marine-Based

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Researchers compared the association between diets high in plant-based omega-3 polyunsaturated fatty acids (PUFAs) vs those high in marine-based PUFAs and the risk for breast cancer.

Obesity and Cancer Risk (Fact Sheet)

Obesity and Cancer Risk (Fact Sheet)

This fact sheet defines obesity and explores its relationship with cancer.

Risk Factors for Arterial, Venous Thrombosis Differ in Polycythemia Vera

Risk Factors for Arterial, Venous Thrombosis Differ in Polycythemia Vera

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Researchers assessed outcomes for 587 patients with PV to determine the risk factors most likely to predict arterial or venous thrombosis in this patient population.

Imaging Management of Breast Density, a Controversial Risk Factor for Breast Cancer

Imaging Management of Breast Density, a Controversial Risk Factor for Breast Cancer

[Cancer Control] This research reviews the evidence regarding breast density as a risk factor for the development of breast cancer and presents a management strategy for screening women with dense breasts.

Risk of Some Cancers Higher in Women With a History of Periodontal Disease

Risk of Some Cancers Higher in Women With a History of Periodontal Disease

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A study on a cohort of women enrolled in the WHI-OS shows that those with a history of periodontal disease had a higher risk for developing some cancers.

Risk of Arterial Thromboembolism Greater With First-Time Cancer

Risk of Arterial Thromboembolism Greater With First-Time Cancer

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An increase in risk for arterial thromboembolism was correlated with cancer stage and varied by cancer type.

Risk of Nonmelanoma Skin Cancers Increased With Alcohol Consumption

Risk of Nonmelanoma Skin Cancers Increased With Alcohol Consumption

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Researchers found that an association between alcohol consumption and nonmelanoma skin cancers may be dose-dependent. This risk includes basal cell carcinoma and cutaneous squamous cell carcinoma.

Risk of Lung Cancer Increases With Diets Higher in Saturated Fats

Risk of Lung Cancer Increases With Diets Higher in Saturated Fats

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A recent study demonstrated that eating a diet high in saturated fats and low in polyunsaturated fats may increase a person's risk of developing lung cancer.

Cancer Risk Not Increased by Childhood Exposure to Diagnostic Radiation

Cancer Risk Not Increased by Childhood Exposure to Diagnostic Radiation

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Risk of developing cancer as a result of childhood exposure to medical imaging radiation is not increased in children or adults, a new study reports.

CVD Risk Factors Identified in Long-Term Survivors of Pediatric Cancer

CVD Risk Factors Identified in Long-Term Survivors of Pediatric Cancer

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Study implicates higher doses of cardiac radiotherapy and exposure to high-dose anthracyclines.

Drinking Coffee Might Reduce Risk of Developing Prostate Cancer

Drinking Coffee Might Reduce Risk of Developing Prostate Cancer

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Men who drank 3 or more cups of Italian style coffee per day had a lower risk of developing prostate cancer.

Position Statement on Fracture Risk With AI Therapy in Early-Stage Breast Cancer Updated

Position Statement on Fracture Risk With AI Therapy in Early-Stage Breast Cancer Updated

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Seven interdisciplinary cancer and bone societies released a position statement updating recommendations for limiting bone loss and fracture risk in patients with early-stage breast cancer undergoing treatment with AIs.

Risk for Disease, Advanced Stage at Diagnosis Higher With Delayed Colonoscopy After Positive FIT Results

Risk for Disease, Advanced Stage at Diagnosis Higher With Delayed Colonoscopy After Positive FIT Results

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Waiting 10 months or longer before follow-up colonoscopy after a positive FIT result is associated with higher risk of disease as well as advanced stage at diagnosis.

Family History Does Not Exclude Active Surveillance as Treatment Option for Prostate Cancer

Family History Does Not Exclude Active Surveillance as Treatment Option for Prostate Cancer

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Family history does not predict aggressiveness of prostate cancer or suitability for active surveillance as a treatment option.

Presence of Protein E6 Predictive of Oropharyngeal Cancer Risk in HPV16-Infected Persons

Presence of Protein E6 Predictive of Oropharyngeal Cancer Risk in HPV16-Infected Persons

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Protein produced by chronically infected cells in persons with HPV16 infection serves as a biomarker for risk of cancer of the oropharynx.

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