Risk Assessment

Firefighters in World Trade Center Attacks Have Increased Risk of Multiple Myeloma

Firefighters in World Trade Center Attacks Have Increased Risk of Multiple Myeloma

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A case series demonstrates the prevalence of MGUS, a precursor condition to multiple myeloma, and subsequent development of MM in white firefighters who responded after the 9/11 attacks in New York City.

Study Determined Association Between Risk of Melanoma, Aspirin Use

Study Determined Association Between Risk of Melanoma, Aspirin Use

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In a review of nearly 200,000 patients from a Midwest metropolitan area, researchers sought to determine if chronic aspirin use would offer the same risk reduction for melanoma as has been seen in various cancers.

Physical Inactivity Linked With Increased Risk of Hodgkin, Non-Hodgkin Lymphoma

Physical Inactivity Linked With Increased Risk of Hodgkin, Non-Hodgkin Lymphoma

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In a case-control study using PEDS data, researchers determined the impact of inactivity on risk for Hodgkin lymphoma and non-Hodgkin lymphoma.

Factoring in Breast Density Improves Long-Term Risk Models for Breast Cancer

Factoring in Breast Density Improves Long-Term Risk Models for Breast Cancer

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A study using a cohort of women from Kaiser Permanente Washington evaluated the accuracy of risk assessment models for breast cancer that included classic risk factors with and without breast density as an additional factor during more than 10 years of follow-up.

Heart-Specific Mortality Not Higher Among Breast Cancer Survivors

Heart-Specific Mortality Not Higher Among Breast Cancer Survivors

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A retrospective cohort study of data from the SEER database assessed the potential risk of cardiac-related mortality in patients with breast cancer, treated with chemotherapy or radiotherapy, vs the general population.

Relative Visceral Fat Area an Indicator of Mortality Risk for Women With RCC

Relative Visceral Fat Area an Indicator of Mortality Risk for Women With RCC

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An evaluation of patients with clear cell renal cell carcinoma revealed greater risk of death for female patients with high relative visceral fat area (rVFA), highlighting the significance of metabolic differences between men and women.

Risk for Cardiovascular Disease Higher in Survivors of Testicular Cancer

Risk for Cardiovascular Disease Higher in Survivors of Testicular Cancer

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Results from the ongoing Platinum Study revealed the prevalence of risk factors for CVD among survivors of testicular cancer who received chemotherapy for their cancer.

Breast Cancer Screening Recommendations Not Completely Reflective of Race, Age

Breast Cancer Screening Recommendations Not Completely Reflective of Race, Age

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An analysis of SEER data sought to examine the appropriateness of age- and race-specific breast cancer screening recommendations for white vs nonwhite women in the United States.

Initiative Aims to Improve Outcomes by Preventing Delirium in Hospitalized Patients

Initiative Aims to Improve Outcomes by Preventing Delirium in Hospitalized Patients

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The effectiveness of twice daily screenings for delirium was investigated in a study presented at the NACNS 2018 Annual Conference.

Cardiotoxicity Risk Greater in Blacks With Breast Cancer Receiving HER2 Therapies

Cardiotoxicity Risk Greater in Blacks With Breast Cancer Receiving HER2 Therapies

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Retrospective study examines the association between risk of cardiotoxicity and race in women with breast cancer receiving chemotherapy and at least 1 year of HER2-targeted therapy.

Distress, Neuroticism Predict Long-term Emotional Distress After Cancer Diagnosis

Distress, Neuroticism Predict Long-term Emotional Distress After Cancer Diagnosis

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A literature sought to identify which signs and symptoms in patients with new cancer diagnoses indicate a greater likelihood for long-term emotional distress.

Arterial Thrombotic Events Associated With First-line Nilotinib for CML in Older Adults

Arterial Thrombotic Events Associated With First-line Nilotinib for CML in Older Adults

A retrospective analysis of patients with CML determined prevalence of arterial thrombotic events in those receiving nilotinib as first-line treatment and prevalence by patient age. Data were presented at ASH 2017.

Risk of Falls, Fractures Greater Among Elderly Patients with Cancer

Risk of Falls, Fractures Greater Among Elderly Patients with Cancer

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Researchers conducted a geriatric assessment of 304 patients with cancer, then followed them in a 2-year study to determine the risk of fractures and falls in older patients.

Oncotype DX Recurrence Score a Potential Marker of Hereditary Breast Cancer

Oncotype DX Recurrence Score a Potential Marker of Hereditary Breast Cancer

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Researchers conducted a review of more than 400 patients with hormone receptor-positive breast cancer to determine if high Oncotype DX RS is associated with a greater likelihood the cancer is hereditary.

Refined Equation May Obviate Oncotype DX in Breast Cancer Treatment Decisions

Refined Equation May Obviate Oncotype DX in Breast Cancer Treatment Decisions

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Research presented at SABCS 2017 demonstrated the effect of refining the linear predictor for determining which patients with breast cancer would potentially benefit from adjuvant chemotherapy.

Compound in Teas, Peas, Soybeans May Increases Prostate Cancer Risk

Compound in Teas, Peas, Soybeans May Increases Prostate Cancer Risk

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An analysis of an intervention arm of the PLCO Cancer Screening Trial evaluated the risk of prostate cancer relative to dietary consumption of isoflavones, a dietary compound found in some plant foods.

Cause of Death More Likely to Be Lung Cancer Than AIDS in Smokers With HIV

Cause of Death More Likely to Be Lung Cancer Than AIDS in Smokers With HIV

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Populating a microsimulation of model of HIV disease, researchers investigated the the likelihood of lung cancer-related morbidity and mortality among patients with HIV who smoke, based on smoking intensity.

Daily Aspirin Reduced Risk of HBV-Related Hepatocellular Carcinoma

Daily Aspirin Reduced Risk of HBV-Related Hepatocellular Carcinoma

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Study presented at the AASLD The Liver Meeting 2017 demonstrated the effect of regular aspirin use on risk of hepatocellular carcinoma in patients with chronic HBV.

PHQ-9 and HADS-D May be Limited in Assessment of MDD in Patients With Cancer

PHQ-9 and HADS-D May be Limited in Assessment of MDD in Patients With Cancer

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Results of a recent study found that the effectiveness of the 9-item Patient Health Questionnaire (PHQ-9) and the Hospital Anxiety and Depression Scale (HADS-D) in screening for major depressive disorder (MDD) in patients with cancer was limited compared to the standardized diagnostic interview.

Cancer Risks for BRCA1/2 Mutation Carriers Determined by Age, Family History, Mutation Location

Cancer Risks for BRCA1/2 Mutation Carriers Determined by Age, Family History, Mutation Location

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Risk assessment study for carriers of the BRCA1/2 mutation identified the factors that influence their risk of developing breast cancer, ovarian cancer, or contralateral breast cancer.

Aspirin Use May Lower Breast Cancer Risk in Women with Diabetes

Aspirin Use May Lower Breast Cancer Risk in Women with Diabetes

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Regular aspirin use is associated with a lower risk of breast cancer among women with diabetes, a recent study from Taiwan has shown.

JAK2 Mutation, Leukocytosis Are Predictive Factors of Thrombosis in Essential Thrombocythemia

JAK2 Mutation, Leukocytosis Are Predictive Factors of Thrombosis in Essential Thrombocythemia

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Presence of JAK2 mutation and leukocytosis are strong predictors for thromboembolic events in patients with essential thrombocythemia (ET).

New Predisposition Genes for Familial Polycythemia Vera Are Identified

New Predisposition Genes for Familial Polycythemia Vera Are Identified

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Predisposition genes for familial polycythemia vera were identified via exome sequencing in a Finnish family with 4 patients.

Distress Management Tool Gets an Update, Patient Version

Distress Management Tool Gets an Update, Patient Version

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A review of the updated NCCN Guidelines is presented with a look at the newly published Guideline for Patients.

Use of Counseling, Surgery Rates Show Limited Physician Knowledge of Breast Cancer Genetic Testing

Use of Counseling, Surgery Rates Show Limited Physician Knowledge of Breast Cancer Genetic Testing

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Limited use of genetic counselors and high rate of double mastectomy in women at average risk with early-stage breast cancer illustrate that understanding of genetic testing results is limited.

Recommendations Against Contralateral Prophylactic Mastectomy Not Tied to Patient Satisfaction

Recommendations Against Contralateral Prophylactic Mastectomy Not Tied to Patient Satisfaction

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Study finds patients are not more likely to report dissatisfaction, seek a second opinion, or change doctors due to physician recommendations against CPM.

Trends in BRCA Mutation Testing Shifting Toward Unaffected Women

Trends in BRCA Mutation Testing Shifting Toward Unaffected Women

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Genetic testing for BRCA gene mutation is increasingly undertaken by women unaffected by breast and/or ovarian cancers.

Risk of Second Cancers Increased in Hodgkin Lymphoma Survivors

Risk of Second Cancers Increased in Hodgkin Lymphoma Survivors

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Hodgkin lymphoma survivors are at higher risk of second cancers, and that risk is even higher in those with a first-degree relative with cancer.

Lifestyle Choices Have Greater Influence on Colon and Rectal Cancer Risk

Lifestyle Choices Have Greater Influence on Colon and Rectal Cancer Risk

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Predictive risk model shows that lifestyle choices have a greater influence on risk for colorectal cancer than does genetic factors.

Comorbidities May Predict Non-Home Discharge After Hysterectomy

Comorbidities May Predict Non-Home Discharge After Hysterectomy

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Presence of 1 risk factor or 2 or more risk factors is associated with non-home discharge after hysterectomy for gynecologic malignancy.

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