RECOMBIVAX HB DIALYSIS Rx

Indications for RECOMBIVAX HB DIALYSIS:

Hepatitis B immunization.

Adults and Children:

Use correct formulation; see literature. Give IM into anterolateral thigh for children; deltoid for adults. May give SC if risk of hemorrhage. Patients 0–19yrs of age (three-dose regimen): give 1^st dose of 5mcg at elected date and repeat after 1 month (2^nd dose) and 6 months after first dose (3^rd dose). Or, for patients 11–15yrs of age, may use alternate two-dose regimen: give 1^st dose of 10mcg at elected date and repeat after 4–6 months (2^nd dose). Patients ≥20yrs of age: give 1^st dose of 10mcg at elected date and repeat after 1 month (2^nd dose) and 6 months after first dose (3^rd dose). Dialysis and pre-dialysis patients: give 1^st dose of 40mcg at elected date and repeat after 1 month (2^nd dose) and 6 months after first dose (3^rd dose); consider booster dose if antibody levels fall to <10mIU/mL. High-risk infants (mother is HBsAg positive or unknown) or if exposed to HBsAg: give hepatitis B immune globulin also (see literature).

Contraindications:

Yeast hypersensitivity.

Warnings/Precautions:

Have epinephrine inj (1:1000) available. Serious active infection. Severely compromised cardiopulmonary status. Pregnancy (Cat.C). Nursing mothers.

See Also:

RECOMBIVAX HB PEDIATRIC/ADOLESCENT

RECOMBIVAX HB ADULT

Pharmacological Class:

HB.

Adverse Reactions:

Local reactions, irritability, fatigue, headache, fever, malaise, nausea, diarrhea, anorexia, pharyngitis, upper respiratory infection, anaphylaxis.

How Supplied:

Single-dose vials: Ped/Adolescent 5mcg/0.5mL (yellow cap)—1, 10; Adult 10mcg/1mL (green cap)—1, 10; Dialysis 40mcg/1mL (blue cap)—1