Radiotherapy

Hypofractionated Radiotherapy After Conservative Surgery May Increase Low-intermediate Grade Late Fibrosis in Breast Cancer Patients

Hypofractionated Radiotherapy After Conservative Surgery May Increase Low-intermediate Grade Late Fibrosis in Breast Cancer Patients

[Breast Cancer: Targets and Therapy] Researchers sought to determine the incidence of subcutaneous side effects in patients with early-stage breast cancer treated with AHF-RT vs standard fractionated RT after breast conserving surgery.

Is Radioimmunotherapy a Path Forward for Melanoma?

Is Radioimmunotherapy a Path Forward for Melanoma?

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Recent research implicates patients' immune cells appear to stimulate radiation abscopal effects, raising the possibility that combining radiotherapy and immunotherapy could yield previously-untapped treatment synergies to improve tumor control.

Combined Microwave Ablation and Minimally Invasive Open Decompression for the Management of Thoracic Metastasis in Breast Cancer

Combined Microwave Ablation and Minimally Invasive Open Decompression for the Management of Thoracic Metastasis in Breast Cancer

[Cancer Management and Research] An investigation into the efficacy of microwave ablation and minimally invasive open decompression treatment for breast cancer with thoracic metastases.

Malnutrition, Decreased QOL Possible After Radiation Therapy for Head and Neck Cancer

Malnutrition, Decreased QOL Possible After Radiation Therapy for Head and Neck Cancer

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In a retrospective study, researchers used established tools to measure the nutritional status of patients with head and neck cancer before, immediately after, and at 2 follow-up points after radiotherapy.

Radiotherapy Outcomes Improved When Breast Cancer CTCs Detectable 

Radiotherapy Outcomes Improved When Breast Cancer CTCs Detectable 

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Researchers explored connections between overall survival and adjuvant radiotherapy when factoring in CTC status.

Smoking During Primary Therapy Worsens Oncologic Outcomes in Prostate Cancer

Smoking During Primary Therapy Worsens Oncologic Outcomes in Prostate Cancer

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A meta-analysis of 11 studies revealed the effects of smoking outcomes of primary radical radiotherapy or radical prostatectomy for prostate cancer.

Internal Benchmarking Improves Nurse Workflow, Staffing in Radiation Oncology

Internal Benchmarking Improves Nurse Workflow, Staffing in Radiation Oncology

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A review of oncology radiation nurse workload led to new benchmarks for staffing and reduced over/under staffing, according to a presentation at the 2018 ONS Annual Congress.

Choosing Wisely After Publication of Level I Evidence in Breast Cancer Radiotherapy

Choosing Wisely After Publication of Level I Evidence in Breast Cancer Radiotherapy

[Breast Cancer: Targets and Therapy] In this retrospective analysis of medical records and estimated costs of treatment, investigators demonstrated that rapid change based on level I evidence is feasible.

Patient Expectations at Odds With Actual Outcomes for Radiotherapy in Breast Cancer

Patient Expectations at Odds With Actual Outcomes for Radiotherapy in Breast Cancer

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Researchers present the results of a survey of patients with breast cancer who underwent radiation therapy to assess the difference between their pretreatment expectations and their actual experience.

Daily IGRT Regimen for Prostate Cancer Improves Rectal Toxicity, Not OS

Daily IGRT Regimen for Prostate Cancer Improves Rectal Toxicity, Not OS

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Researchers present findings of a comparison of daily image-guided radiotherapy (IGRT) vs a weekly regimen in patients with N0 localized prostate cancer at the 2018 GU Cancers Symposium.

Oral Impairment Linked to Reduced QOL in Posttherapy Head and Neck Cancer

Oral Impairment Linked to Reduced QOL in Posttherapy Head and Neck Cancer

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Study compared the effect of treatments on quality of life in treatment-naïve patients with HNC vs those who underwent radiotherapy and/or chemotherapy, and compared with cancer-free patients.

PSPT vs IMRT: Radiation Exposure Reduced in Heart Only

PSPT vs IMRT: Radiation Exposure Reduced in Heart Only

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PSPT significantly reduced radiation exposure to the heart, but no differences were observed between PSPT and IMRT for the lung or esophagus.

Radiotherapy for Esophageal Carcinoma: Dose, Response and Survival

Radiotherapy for Esophageal Carcinoma: Dose, Response and Survival

[Cancer Management and Research] Radiation dose, fractionation strategies, and predictive factors of response to therapy in patients with esophageal carcinoma are reviewed to determine if more intense local therapy would lead to better outcomes and for which patients.

All-Cause Mortality Improved by Advances in Radiotherapy for Hodgkin Lymphoma

All-Cause Mortality Improved by Advances in Radiotherapy for Hodgkin Lymphoma

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Investigators assessed the impact of advances over time in the treatment of Hodgkin lymphoma on all-cause mortality in patients with Hodgkin lymphoma who received radiotherapy alone or with chemotherapy.

Outcomes Similar With Postmastectomy Hypofractionation, Standard Radiation

Outcomes Similar With Postmastectomy Hypofractionation, Standard Radiation

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Researchers report that adjuvant HFRT and adjuvant CFRT offer similar benefits to women with high-risk breast cancer after mastectomy in an oral presentation at the 59th Annual Meeting of ASTRO.

Smoking Increases Long-Term Risks From Radiotherapy in Breast Cancer

Smoking Increases Long-Term Risks From Radiotherapy in Breast Cancer

Risk associated with radiotherapy for breast cancer is substantially reduced with smoking cessation.

ASTRO Issues Updated Guidelines on Palliative Radiation Therapy

ASTRO Issues Updated Guidelines on Palliative Radiation Therapy

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The guideline recommends optimal RT dosing schedules for pain relief, including options for retreatment.

Short-Course Radiation With Delay to Surgery Improves Outcomes in Rectal Cancer

Short-Course Radiation With Delay to Surgery Improves Outcomes in Rectal Cancer

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Outcomes improved with short-course radiation and delay to surgery of 4 to 8 weeks.

QoL, Pain from Bone Metastases May Improve as Early as 10 Days After RT

QoL, Pain from Bone Metastases May Improve as Early as 10 Days After RT

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A single 8-Gy dose of radiotherapy for painful bone metastases may improve quality of life and pain as early as 10 days after administration.

GARD: A Move Toward Precision Radiation Therapy

GARD: A Move Toward Precision Radiation Therapy

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A new tool may enable oncologists to deliver radiation therapy targeted to a tumor's biology and radiosensitivity, similar to how anticancer agents target specific tumor mutation-affected gene pathways.

Panitumumab Plus Accelerated RT Not Effective for Locoregionally Advanced HNSCC

Panitumumab Plus Accelerated RT Not Effective for Locoregionally Advanced HNSCC

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Progression-free survival with panitumumab plus accelerated-fractionation radiotherapy was compared with that of cisplatin plus standard-fractionation radiotherapy in patients with locoregionally advanced HNSCC in a recently published study.

Omitting RT in Certain Older Women With Early Breast Cancer is Safe

Omitting RT in Certain Older Women With Early Breast Cancer is Safe

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Researchers report their study findings on the safety of omitting radiotherapy after breast-conserving surgery, sentinel node biopsy, and adjuvant endocrine therapy in older patients with early breast cancer and favorable histopathology at SABCS 2016.

Pilot Study Assesses Feasibility of Nurse-led Sexual Rehabilitation Program

Pilot Study Assesses Feasibility of Nurse-led Sexual Rehabilitation Program

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Researchers report on the feasibility of a nurse-led sexual rehabilitation intervention to target sexual recovery and vaginal dilation in women who underwent pelvic radiation therapy and brachytherapy for gynecologic cancers.

Study Supports Routine Use of IMRT for Locally Advanced NSCLC

Study Supports Routine Use of IMRT for Locally Advanced NSCLC

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IMRT was associated with lower rates of severe pneumonitis and cardiac doses compared with 3D-CRT in patients with locally advanced NSCLC.

Patients Receiving RT in APBI Facilities Despite Eligibility for Observation

Patients Receiving RT in APBI Facilities Despite Eligibility for Observation

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Patients with early stage breast cancer who received breast-conserving surgery and were eligible for observation were more likely to undergo adjuvant radiotherapy in facilities performing APBI.

ASCO, ASTRO Issue Guideline Update for Postmastectomy RT

ASCO, ASTRO Issue Guideline Update for Postmastectomy RT

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The American Society of Clinical Oncology, American Society for Radiation Oncology, and Society of Surgical Oncology have issued a joint consensus guideline update for the use of radiotherapy following mastectomy in patients with breast cancer.

WBRT Adds Little Benefit for NSCLC With Brain Metastases

WBRT Adds Little Benefit for NSCLC With Brain Metastases

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Adding WBRT to dexamethasone and best supportive care provides little additional benefit for patients with NSCLC and brain metastases who are ineligible to undergo resection or stereotactic radiotherapy.

Study Evaluates Systemic Therapy Use With RT Among Older Patients With Head and Neck Cancer

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In contrast of available prospective data, most older patients with locoregionally advanced head and neck cancer are treated with definitive radiotherapy also receive systemic therapy.

Postop RT Deferral Associated With Worse Survival in Children With Medulloblastoma

Postop RT Deferral Associated With Worse Survival in Children With Medulloblastoma

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Despite the use of adjuvant chemotherapy, deferral of postoperative radiotherapy is associated with worse survival in pediatric patients with medulloblastoma.

Functional Status Linked to Treatment Choice for Prostate Cancer

Functional Status Linked to Treatment Choice for Prostate Cancer

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Functional status, a person's ability to perform normal activities of daily living, is associated with treatment choice for patients with prostate cancer.

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