Multiple Treatment Modalities for Brain Metastasis in Patients With EGFR-mutant Non-small Cell Lung CancerMay 25, 2018
[OncoTargets and Therapy] Researchers examined the efficacy of EGFR-TKIs in treating with EGFR-mutant NSCLC and brain metastases.
[Lung Cancer: Targets and Therapy] This research examines the role of GLI1, a transcriptional regulator, in cancer care.
[Cancer Management and Research] A review of marginal zone lymphomas, a common and varied group of hematologic malignancies, and their treatment, with a focus on the Bruton's tyrosine kinase ibrutinib.
[Gastrointestinal Cancer: Targets and Therapy] This review presents the most up-to-date molecular, clinical, and therapeutic data, including an overview of a current phase 3 study assessing the efficacy of simultaneous BRAF, EGFR, and MEK inhibition among patients with BRAFV600E-mutant CRC.
Clinicopathological Features and Prognosis in Elderly Gastric Cancer Patients: A Retrospective Cohort StudyApril 27, 2018
[OncoTargets and Therapy] A retrospective study assessed patients with gastric cancer, identifying disease characteristics more prevalent in elderly patients and the effect on prognosis for these patients.
[Breast Cancer: Targets and Therapy] Researchers present a review of the LHRH agonist triptorelin and the use of this agent to induce chemical castration in estrogen-sensitive breast cancer tumors in younger women.
Bax, Bcl-2, and Bax/Bcl-2 as Prognostic Markers in Acute Myeloid Leukemia: Are We Ready for Bcl-2-Directed Therapy?April 13, 2018
[Cancer Management and Research] This report presents an assessment of the relationship of Bax/Bcl-2 expression and the clinical response of patients with AML treated with cytarabine plus daunorubicin, and their potential as biomarkers to predict chemotherapeutic outcomes.
[Gastrointestinal Cancer: Targets and Therapy] This review discusses novel tools and newer technologies that have been employed to address iCCA.
[Breast Cancer: Targets and Therapy] In this retrospective analysis of medical records and estimated costs of treatment, investigators demonstrated that rapid change based on level I evidence is feasible.
[OncoTargets and Therapy] A meta-analysis was conducted to evaluate the effect of abnormal EGFR expression on overall survival (OS) in patients with glioma.
[Journal of Gastrointestinal Oncology] A review of diagnostic parameters and management modalities for checkpoint inhibitor-induced hepatic toxicity is presented.
[OncoTargets and Therapy] This review examines the rationale of olaratumab in the treatment of advanced soft-tissue sarcomas and its emerging role in clinical practice.
[Cancer Management and Research] The presence of comorbidities is thought to play a significant role in the decision to treat patients with NSCLC, and this impacts survival.
[Breast Cancer: Targets and Therapy] A review of studies investigating the efficacy of buparlisib monotherapy and in combination with various other anticancer agents in the treatment of breast cancer and other solid tumors.
Efficacy and Safety of COX-2 Inhibitors for Advanced Non-small-cell Lung Cancer With Chemotherapy: A Meta-analysisFebruary 16, 2018
[OncoTargets and Therapy] This meta-analysis assesses the efficacy and safety profile of COX-2 inhibitors in patients with advanced non-small-cell lung cancer.
[Cancer Management and Research] A review of vulvar carcinoma and treatment options for patients with rare gynecologic cancer.
Comparative Study of Clinical Efficacy Using Three-dimensional and Two-dimensional Laparoscopies in the Treatment of Distal Gastric CancerFebruary 02, 2018
[OncoTargets and Therapy] This study investigated the safety and feasibility of 3D laparoscopic-assisted radical gastrectomy for distal advanced gastric cancer vs 2D laparoscopic surgery, results of this study have shown.
[Cancer Management and Research] Radiation dose, fractionation strategies, and predictive factors of response to therapy in patients with esophageal carcinoma are reviewed to determine if more intense local therapy would lead to better outcomes and for which patients.
Feasibility and Outcomes of Modified Enhanced Recovery After Surgery for Nursing Management of Aged Patients Undergoing EsophagectomyJanuary 19, 2018
[Journal of Thoracic Disease] A randomized study investigated whether an mERAS protocol could result in improved recovery of aged patients with esophageal cancer undergoing esophagectomy.
Comparison of Survival Outcomes Between Radical Hysterectomy and Definitive Radiochemotherapy in Stage IB1 and IIA1 Cervical CancerJanuary 12, 2018
[Cancer Management and Research] A comparison study evaluated whether radical hysterectomy or radiochemotherapy provides superior survival outcomes for patients with stage IB1 or IIA1 cervical cancer.
[Breast Cancer: Targets and Therapy] Researchers present a review of study findings on the effect of statins on clinical outcomes for patients with breast cancer.
Male Occult Triple-negative Breast Cancer With Dermatomyositis: A Case Report and Review of the LiteratureDecember 29, 2017
[OncoTargets and Therapy] In this case report, a patient with male breast cancer developed dermatomyositis.
Capecitabine and Oxaliplatin as First and Second Line Treatment for Locally Advanced and Metastatic Pancreatic Ductal AdenocarcinomaDecember 22, 2017
[Journal of Gastrointestinal Oncology] This research evaluates the use of capecitabine and oxaliplatin (CAPOX) for first or second-line treatment of locally advanced or metastatic PDAC.
Clinical Aspects of Foot Health and Their Influence on Quality of Life Among Breast Cancer Survivors: A Case-control StudyDecember 15, 2017
[Cancer Management and Research] Researchers determined the effect of breast cancer and its treatment on quality of life relative to foot health issues.
Optimal Therapy for Patients with Hepatocellular Carcinoma and Resistance or Intolerance to Sorafenib: Challenges and SolutionsDecember 08, 2017
[Journal of Hepatocellular Carcinoma] This research examines systemic therapies that can be considered in patients with sorafenib refractory hepatocellular carcinoma.
Nab-paclitaxel/carboplatin Induction in Squamous NSCLC: Longitudinal Quality of Life While on ChemotherapyDecember 01, 2017
[Lung Cancer: Targets and Therapy] Researchers examine the affect of first-line nab-paclitaxel plus carboplatinon QoL for patients with advanced non-small cell lung cancer.
Practical Management of Adverse Events Associated With Cabozantinib Treatment in Patients With Renal-cell CarcinomaNovember 24, 2017
[OncoTargets and Therapy] This research reviews the management of the more common adverse events associated with cabozantinib treatment for patients with patients with advanced clear-cell renal-cell carcinoma.
A Structured Group Exercise Program for Patients With Metastatic Cancer Receiving Chemotherapy and CTNNB1 (β-catenin) as a Biomarker of Exercise EfficacyNovember 17, 2017
[Cancer Management and Research] This research explores the feasibility of group exercise intervention using strength and aerobic training for patients with metastatic cancer undergoing chemotherapy.
[Cancer Management and Research] This study examines the advances that pembrolizumab has made in melanoma and upcoming research that may further improve melanoma treatment.
[OncoTargets and Therapy] A review of the role of chemotherapy in the treatment of Merkel cell carcinoma in view of the recent FDA approval of the PD-L1 antibody avelumab and limited and controversial data on the efficacy of chemotherapy in this disease.
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- Multimodal Follow-up Improved Postradiotherapy Sexual Health in Lower GI, Gynecologic Cancers
- Panobinostat vs Placebo: Patient-Reported Outcomes Comparable in Multiple Myeloma
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- Hair Dyes and Cancer Risk (Fact Sheet)
- Low Level Laser Therapy May Prevent Oral Mucositis During HSCT Conditioning
- Counseling Intervention That Improved CHD is Applied to Cancer Risk in Men
- Low-fat Diet May Improve Overall Survival in Newly Diagnosed Breast Cancer
- Multiple Treatment Modalities for Brain Metastasis in Patients With EGFR-mutant Non-small Cell Lung Cancer
- IDDS and SCS: Exploring Multimodal Approaches for Managing Cancer Pain
- Avoiding the ED: Planned Strategies for Unplanned Urgent Cancer Care
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