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PENTASA
Colorectal disorders
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Drug Name:

PENTASA Rx

Generic Name and Formulations:
Mesalamine 250mg, 500mg; controlled-rel caps.

Company:
Shire US, Inc.

Therapeutic Use:

Indications for PENTASA:

Mildly-to-moderately active ulcerative colitis.

Adult:

Swallow whole; may open caps and sprinkle entire contents onto applesauce or yogurt, consume immediately. 1g four times daily for up to 8 weeks.

Children:

Not established.

Warnings/Precautions:

Discontinue if acute intolerance syndrome is suspected. Atopic dermatitis or eczema: may have more severe photosensitivity reactions. Renal disease; monitor SCr, BUN, proteinuria. Hepatic impairment. Pregnancy (Cat.B). Nursing mothers.

Pharmacological Class:

Salicylate.

Interactions:

May interfere with urinary normetanephrine test by liquid chromatography; consider alternative assay.

Adverse Reactions:

Diarrhea, headache, nausea, abdominal pain, dyspepsia, vomiting, rash; nephrotoxicity.

How Supplied:

Caps 250mg—240; 500mg—120

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