Pediatric Oncology

Seeking an Explanation for the Lack of Research Focused in Pediatric Oncology Therapeutics

Seeking an Explanation for the Lack of Research Focused in Pediatric Oncology Therapeutics

By

Researchers sought an explanation for the paucity of research, drug development, and clinical trials focusing specifically on cancer in pediatric populations.

Metronidazole, Vancomycin Recommended for <i>C Difficile</i> in Pediatric Oncology, HSCT

Metronidazole, Vancomycin Recommended for C Difficile in Pediatric Oncology, HSCT

By

An international multidisciplinary panel of experts in pediatric oncology and infectious diseases convened to develop recommendations for the prevention and treatment of C difficile infection in pediatric patients with cancer or who are undergoing HSCT.

Experiencing Parental Cancer As Child Can Have Lasting Impact

Experiencing Parental Cancer As Child Can Have Lasting Impact

An increased risk of low educational attainment and attenuation in income at age 30 years has been observed in those that have experienced parental cancer.

Too Much Physical Activity During Therapy for Pediatric ALL Decreases Cognitive Function

Too Much Physical Activity During Therapy for Pediatric ALL Decreases Cognitive Function

By

Using a longitudinal parallel-process model, researchers evaluated the impact of physical activity on symptoms, physical activity, and cognitive function in children with ALL undergoing chemotherapy.

Pediatric Cancer Survival in Racial, Ethnic Groups May Be Influenced by Socioeconomics

Pediatric Cancer Survival in Racial, Ethnic Groups May Be Influenced by Socioeconomics

By

Researchers accessed the SEER database and evaluated the population-based cancer survival data of 31,866 pediatric patients between the ages of 0 and 19.

Lorazepam Did Not Improve CINV in Pediatric Acute Lymphoblastic Leukemia

Lorazepam Did Not Improve CINV in Pediatric Acute Lymphoblastic Leukemia

By

A retrospective chart review was conducted to determine if adding lorazepam to granisetron would improve CINV prevention in pediatric patients with newly diagnosed ALL.

Interim Data Shows Romiplostim May Lead to Positive Long-Term Response in Pediatric ITP

Interim Data Shows Romiplostim May Lead to Positive Long-Term Response in Pediatric ITP

By

In a poster presentation at the 23rd Congress of EHA, researchers described a study of the efficacy of romiplastim in achieving a platelet response in pediatric patients with immune thrombocytopenia.

Dexrazoxane May Reduce Cardiotoxicity in Pediatric AML

Dexrazoxane May Reduce Cardiotoxicity in Pediatric AML

By

Children's Oncology Group study reported on the effect of dexrazoxane on cardiotoxicity of anthracycline-containing regimens in pediatric patients with AML at the 2018 ASCO Annual Meeting.

Cancer in Children and Adolescents (Fact Sheet)

Cancer in Children and Adolescents (Fact Sheet)

This fact sheet reviews cancer in adolescents and children, including possible causes, treatment, and the general outlook for childhood cancers.

Long-term Impact of Retinoblastoma Therapy on Vision-Related Quality of Life

Long-term Impact of Retinoblastoma Therapy on Vision-Related Quality of Life

By

Using the NEI-VFQ-25, researchers assessed vision-targeted health-related quality of life for survivors of retinoblastoma.

18F-FDG PET/CT Accurately Identifies Bone Marrow Involvement in Pediatric Hodgkin's Lymphoma

18F-FDG PET/CT Accurately Identifies Bone Marrow Involvement in Pediatric Hodgkin's Lymphoma

By

Researchers conducted a retrospective study to assess 18F-FDG PET/CT vs bone marrow biopsy to detect bone marrow involvement among pediatric patients with Hodgkin lymphoma.

Oncology Clinicians Disagree on School Attendance for Children With Cancer 

Oncology Clinicians Disagree on School Attendance for Children With Cancer 

By

A survey of oncology providers demonstrated a mix of opinions as to whether immunosuppressed children with cancer should attend school.

Palonosetron Noninferior to Ondansetron for Pediatric Chemotherapy-induced Vomiting

Palonosetron Noninferior to Ondansetron for Pediatric Chemotherapy-induced Vomiting

By

In a prospective study, researchers sought to determine the noninferiority of palonosetron to ondansetron in pediatric patients with cancer receiving moderate or high emetogenic chemotherapy.

FDA Expands Nilotinib Indication to Include Pediatric Chronic Myeloid Leukemia

FDA Expands Nilotinib Indication to Include Pediatric Chronic Myeloid Leukemia

By

Based on results of 2 prospective studies, the FDA approved the use of nilotinib in pediatric patients older than 1 year with newly diagnosed Ph+ CML-CP and those with TKI-intolerant or resistant disease.

Managing Chemo Brain in Pediatric Survivors of Childhood Cancer

Managing Chemo Brain in Pediatric Survivors of Childhood Cancer

By

Reintegration to the general environment, particularly to school, can be challenging for survivors of childhood cancers. This review discusses how adverse effects such as chemo brain may present extra challenges for these patients and what can be done to ease patients' anxiety.

Higher Incidence, Risk of Some Cancers Seen After Childhood Pneumonia

Higher Incidence, Risk of Some Cancers Seen After Childhood Pneumonia

Children who were hospitalized with pneumonia may be at higher risk of certain cancer types.

Tisagenlecleucel Produces Durable Remissions in Pediatric, Young Adult B-cell ALL

Tisagenlecleucel Produces Durable Remissions in Pediatric, Young Adult B-cell ALL

By

A previous single-site trial showed that patients with R/R B-cell ALL treated with tisagenlecleucel achieved high complete remission rates. In this study, investigators report on results after the scope of the study was expanded.

Specialized Pediatric Palliative Care Reduces High-Intensity Care at End of Life

Specialized Pediatric Palliative Care Reduces High-Intensity Care at End of Life

By

A retrospective study of data from POGONIS evaluated the effectiveness of specialized pediatric palliative care vs general palliative care or no palliative care in pediatric patients with cancer at the end of life.

Survey Reveals Opinions, Barriers Regarding Medical Marijuana Use in Children

Survey Reveals Opinions, Barriers Regarding Medical Marijuana Use in Children

A survey of pediatric oncology providers including physicians, nurses, and social workers reveals their willingness to consider medical marijuana for children with cancer, as well as their reasons against its use in these patients.

History of Headache, Vomiting, Seizures Associated With Pediatric Brain Cancer

History of Headache, Vomiting, Seizures Associated With Pediatric Brain Cancer

By

Research pinpointed clinical factors, such as headache, that may be associated with pediatric brain neoplasms.

Fosaprepitant Improves Standard Antiemetic Therapy in Pediatric Patients

Fosaprepitant Improves Standard Antiemetic Therapy in Pediatric Patients

By

Data presented at ASH 2017 illustrates the effectiveness of 2 prophylactic antiemetic regimens in pediatric patients receiving moderately or highly emetogenic chemotherapy.

4R+3Dex Regimen May Lead to Durable Complete Response in Pediatric Chronic ITP

4R+3Dex Regimen May Lead to Durable Complete Response in Pediatric Chronic ITP

By

Young patients with chronic ITP may experience relapse within 5 years of completing therapy. In this study, investigators sought to determine if the 4R+3Dex regimen for chronic ITP would improve response rates in pediatric patients with the disease.

Reduced Delayed Intensification Impacts Risk of Pediatric ALL Relapse

Reduced Delayed Intensification Impacts Risk of Pediatric ALL Relapse

By

Improved survival in pediatric patients with standard-risk ALL has shifted the focus toward reducing treatment burden and toxicity; therefore, researchers sought to determine the effects of reduced DI chemotherapy on relapse and survival.

Dasatinib Granted Regular FDA Approval for Ph+ CML in Pediatric Patients

Dasatinib Granted Regular FDA Approval for Ph+ CML in Pediatric Patients

By

US FDA approval of dasatinib is extended to pediatric patients with Ph+ CML based on data from 2 open-label, nonrandomized trials involving 97 patients.

Current, Emerging Systemic and Targeted Therapies for Pediatric Leukemia: A Review

Current, Emerging Systemic and Targeted Therapies for Pediatric Leukemia: A Review

By

In this review, investigators discuss current and emerging treatments for acute lymphocytic leukemia and acute myeloid leukemia in pediatric patients.

Cancer Risk Not Increased by Childhood Exposure to Diagnostic Radiation

Cancer Risk Not Increased by Childhood Exposure to Diagnostic Radiation

By

Risk of developing cancer as a result of childhood exposure to medical imaging radiation is not increased in children or adults, a new study reports.

Screening Recommendations for Children with Common Cancer Predisposition Syndromes

Screening Recommendations for Children with Common Cancer Predisposition Syndromes

By

The Pediatric Cancer Working Group of the AACR released its first consensus screening guidelines for children with common cancer predisposition syndromes.

Self-Reports on Adverse Effects From Younger Patients Are Reliable, Accurate

Self-Reports on Adverse Effects From Younger Patients Are Reliable, Accurate

By

Children and adolescent patients with cancer are able to accurately report subjective adverse events (AEs) they experience during their cancer treatment, and they are willing to do so.

Checkpoint Inhibitors Appear Safe for Pediatric Cancer Patients

Checkpoint Inhibitors Appear Safe for Pediatric Cancer Patients

By

The medications so far show little efficacy in children with cancer, but new studies may provide clues to how to change this, pediatric oncologist says.

Sign Up for Free e-newsletters



Regimen and Drug Listings

GET FULL LISTINGS OF TREATMENT Regimens and Drug INFORMATION

Bone Cancer Regimens Drugs
Brain Cancer Regimens Drugs
Breast Cancer Regimens Drugs
Endocrine Cancer Regimens Drugs
Gastrointestinal Cancer Regimens Drugs
Genitourinary Cancer Regimens Drugs
Gynecologic Cancer Regimens Drugs
Head and Neck Cancer Regimens Drugs
Hematologic Cancer Regimens Drugs
Lung Cancer Regimens Drugs
Other Cancers Regimens
Rare Cancers Regimens
Skin Cancer Regimens Drugs