Combination therapy with lenvatinib and pembrolizumab is granted Breakthrough Therapy Designation for the treatment of advanced or metastatic renal cell carcinoma (RCC).
Two studies evaluate use of deep learning algorithm; one for breast cancer, the other for diabetic retinopathy
Median overall survival from time of diagnosis has increased from 7.5 to 22.7 months in the last decade.
A recent study found that nodal tumors and distant metastases originate from different areas of the primary tumor, suggesting that cancer spreads independently of the lymph nodes.
Patients with metastatic kidney cancer may also have an primary lung cancer that has gone gone undiagnosed.
Treatment expectations of individuals with metastatic prostate cancer and their health care providers often do not match.
Gastric and Colon Metastasis From Breast Cancer: Case Report, Review of the Literature, and Possible Underlying MechanismsFebruary 03, 2017
[Breast Cancer: Targets and Therapy] This research presents a case report of patient with gastrointestinal metastases from breast cancer.
Treatment options for brain metastases in patients with EGFR-mutant NSCLC include SRS, WBRT, and EGFR TKIs. In this study, researchers sought to determine the optimal treatment approach of those who develop brain metastases and have not received EFGR TKIs.
Race is not associated with the development of metastases in patients with nonmetastatic castration-resistant prostate cancer (CRPC), according to a recently published study.
Longer survival was achieved with stereotactic radiosurgery (SRS) alone than with whole-brain radiation therapy (WBRT) in patients with fewer than 4 brain metastases from NSCLC or breast cancer.
Patients with melanoma who undergo surgical resection of abdominal metastases live more than twice as long as those treated with drug therapy alone, according to novel research presented at the American College of Surgeons Clinical Congress 2015.
A new study finds that, while brain metastases share some genetic characteristics with the primary tumors from which they originated, they also carry unique genetic mutations, indicating that the evolutionary pathways of the metastatic and the primary tumors have diverged, which may change sensitivities to targeted therapy drugs.
Metastases cause the vast majority of cancer deaths, but their tiny seeds are so difficult to track. Now, scientists described studying individual metastatic cells from human breast cancer tumors implanted into mice as the cells escaped into the blood stream and began to form tumors elsewhere in the body.
A blood test that involves examination of cell-free circulating DNA could be key to earlier detection of breast cancer metastases.
Addition of SIRT Fails to Improve Overall Progression-free Survival in Colorectal Cancer Liver MetastasesMay 31, 2015
Addition of selective internal radiation therapy (SIRT) failed to improve progression-free survival in non-resectable colorectal cancer liver metastases.
A combination of radiofrequency ablation and systemic chemotherapy was associated with improved long-term overall survival in patients with unresectable colorectal cancer liver metastases, according to data presented at the 2015 American Society of Clinical Oncology annual meeting.
Patients with cancer and brain metastases who develop blood clots may safely receive enoxaparin.
New evidence indicates that immune checkpoint inhibitors may work in glioblastoma and brain metastases.
A blue-ribbon team of national experts on brain cancer said that professional pessimism and out-of-date myths rather than current science may compromise the care of patients with cancer that has metastasized to the brain.
Survival improved by stereotactic radiosurgery alone in adults under 50 years with limited brain metastasesOctober 09, 2013
Overall survival was improved for adults age 50 years and younger with brain cancer who were treated with stereotactic radiosurgery that was not combined with whole-brain radiotherapy.
Measuring levels of the molecule microRNA-31 might accurately determine if a patient's lung cancer has spread to nearby lymph nodes.
ATF3 expression in stromal mononuclear cells correlates with clinical outcomes and predicts death.
Cellular therapy and gene therapy have been successfully combined in a mouse model to develop a viable treatment strategy for breast cancer that has spread to a patient's brain.
Breast tumors that carry breast cancer stem and progenitor cells with mutations in specific oncogenes are significantly more likely than other breast cancers to metastasize to the lymph nodes, researchers reported.
Both milky spots and fat cells in the omentum promote cancer cell migration, growth, and spread, reports new research. Results from a series of experiments have suggested a two-step model of omental colonization.
After a breast cancer operation, the removed tumor is always examined, as its subtype can provide an indication of how aggressive the disease is.
MicroRNA levels were increased in serum from patients with adenoma, CRC; but drop after curative surgery.
Regulatory T (Treg) cells that infiltrate tumors express proteins that can serve as targets for therapeutic antibodies, suggesting that treatments aimed at these immune cells could be a promising approach in cancer treatment.
The long-standing mystery about what activates dormant disseminated breast cancer tumor cells after years and even decades of latency may have been solved.
Recently, researchers analyzed metastatic gastric cancer cases from the SEER database to help determine which treatment options offer the best survival possibilities.
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