aHSCT Should Be Standard of Care for HIV-Related Lymphoma

Share this content:
aHSCT Should Be Standard of Care for HIV-Related Lymphoma
aHSCT Should Be Standard of Care for HIV-Related Lymphoma

(HealthDay News) -- Patients living with HIV are at high risk for lymphoma, and, according to a study published online June 13 in Blood, autologous hematopoietic stem-cell transplantation (aHSCT) should be standard treatment in these cases.

For the study, Joseph Alvarnas, M.D., an associate clinical professor of hematology at City of Hope National Medical Center in Duarte, Calif., and colleagues recruited 40 patients with HIV and lymphoma and 151 lymphoma patients without HIV. Patients in both groups received aHSCT.

The researchers found that the overall survival among the patients with HIV was 87.3 percent after one year and 82 percent after two years. That compared with 87.7 percent one-year survival of patients without HIV. The rate of transplant-related mortality among HIV patients was 5.2 percent. That rate was also comparable to patients without the virus. And one year after transplant, 82.6 percent of patients with HIV maintained undetectable levels of the virus.

"These findings are remarkably important for a group of patients who, up until now, have been inconsistently treated," Alvarnas said in a news release from the American Society of Hematology. "Based on our data, autologous stem cell transplant should be considered the standard of care for patients with HIV-related lymphomas for the same indications and under the same circumstances that we would use it in patients without HIV infection."

Full Text (subscription or payment may be required)

You must be a registered member of ONA to post a comment.

Sign Up for Free e-newsletters

Regimen and Drug Listings


Bone Cancer Regimens Drugs
Brain Cancer Regimens Drugs
Breast Cancer Regimens Drugs
Endocrine Cancer Regimens Drugs
Gastrointestinal Cancer Regimens Drugs
Genitourinary Cancer Regimens Drugs
Gynecologic Cancer Regimens Drugs
Head and Neck Cancer Regimens Drugs
Hematologic Cancer Regimens Drugs
Lung Cancer Regimens Drugs
Other Cancers Regimens
Rare Cancers Regimens
Skin Cancer Regimens Drugs