Lung Cancer

Preventative Medications Unnecessarily Prescribed to EOL Patients With Lung Cancer

Preventative Medications Unnecessarily Prescribed to EOL Patients With Lung Cancer

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In a retrospective study conducted in the United States and the United Kingdom, researchers evaluated the prescribing of preventative medications in patients with lung cancer discharged from hospital at the end of life.

Using Palliative Care to Improve Lung Cancer Outcomes in Veterans at Risk of Suicide

Using Palliative Care to Improve Lung Cancer Outcomes in Veterans at Risk of Suicide

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In a review of data from more than 20,000 veterans, researchers determined the effects of palliative care on suicide rates among veterans with advanced lung cancer.

Pembrolizumab Combination for Metastatic NSCLC Upgraded to Full FDA Approval

Pembrolizumab Combination for Metastatic NSCLC Upgraded to Full FDA Approval

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FDA upgraded the approval of pembrolizumab in combination with pemetrexed and platinum chemotherapy as a first-line treatment for patients with metastatic, nonsquamous NSCLC with no EGFR or ALK genomic tumor aberrations from accelerated to regular approval.

Oral Hydration Effectively Reduced Risk of Nephrotoxity After Cisplatin

Oral Hydration Effectively Reduced Risk of Nephrotoxity After Cisplatin

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A single-center retrospective study determined the safety of IV hydration before and oral hydration after cisplatin therapy to prevent nephrotoxicity in patients with lung cancer vs IV hydration both before and after therapy.

New PDL1 Inhibitors for Non-small Cell Lung Cancer: Focus on Pembrolizumab

New PDL1 Inhibitors for Non-small Cell Lung Cancer: Focus on Pembrolizumab

[OncoTargets and Therapy] Evidence increasingly suggests that pembrolizumab has a significant role in first- and second-line therapy for NSCLC. This review presents the results of previous and ongoing studies and discusses biomarkers that can potentially identify eligible candidates for treatment with the PD-L1 inhibitor.

Mortality Rates for Lung Cancer Likely to Surpass Breast Cancer Among Women by 2030

Mortality Rates for Lung Cancer Likely to Surpass Breast Cancer Among Women by 2030

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Screening practices and smoking habits are expected to have a significant impact on mortality rates for lung cancer and breast cancer among women in high-income countries.

Link Between Asbestos-Free Talcum Powder and Cancer Unclear

Link Between Asbestos-Free Talcum Powder and Cancer Unclear

Studies conducted in people have mixed results, with some indication of increased risk of ovarian cancer.

Lung Cancer Screening: Effective Models for Selecting the Most Candidates at Highest Risk

Lung Cancer Screening: Effective Models for Selecting the Most Candidates at Highest Risk

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Four of 9 lung cancer screening models were shown to effectively select the most appropriate candidates for low-dose CT lung cancer screening among US ever-smokers.

Lung Cancer: What Nurse Navigators Need to Know in 2018

Lung Cancer: What Nurse Navigators Need to Know in 2018

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There have been many recent changes in lung cancer, including updated early detection possibilities and changes in diagnostic procedures, reporting, and treatment options. These are reviewed in a presentation at the 2018 ONA Navigation Summit.

Radiation-Induced Esophagitis: A Common, Debilitating Clinical Challenge in Thoracic Radiotherapy

Radiation-Induced Esophagitis: A Common, Debilitating Clinical Challenge in Thoracic Radiotherapy

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A review of current options and ongoing trials for managing ARIE, a common esophageal adverse effect caused by radiotherapy to the thoracic region for lung, breast, or head and neck cancers, or lymphoma.

Ado-trastuzumab Emtansine Effective in HER2 Amplified Non-breast, Non-gastric Cancers

Ado-trastuzumab Emtansine Effective in HER2 Amplified Non-breast, Non-gastric Cancers

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Study results presented at 2018 ASCO Annual Meeting demonstrated effectiveness of ado-trastuzumab emtansine in non-breast non-gastric HER2-amplified cancers.

Response to Rapamycin Analogs but not PD-1 Inhibitors in PTEN-mutated Metastatic Non-small Cell Lung Cancer With High Tumor Mutational Burden

Response to Rapamycin Analogs but not PD-1 Inhibitors in PTEN-mutated Metastatic Non-small Cell Lung Cancer With High Tumor Mutational Burden

[Lung Cancer: Targets and Therapy] This case study demonstrates that genomic profiling may still benefit patients who fail checkpoint inhibitor therapy despite having high tumor mutational burden and PD-L1 positivity.

Lung Cancer Incidence is Higher for Young Women Than Young Men

Lung Cancer Incidence is Higher for Young Women Than Young Men

Researchers observed a decrease in the age-specific incidence of lung cancer among both men and women aged 30 to 54 years over the past two decades; the declines among men were steeper.

Multiple Treatment Modalities for Brain Metastasis in Patients With EGFR-mutant Non-small Cell Lung Cancer

Multiple Treatment Modalities for Brain Metastasis in Patients With EGFR-mutant Non-small Cell Lung Cancer

[OncoTargets and Therapy] Management of brain metastases in patients with EGFR-mutant NSCLC is controversial. In this study, researchers find combination and sequential treatment with EGFR-TKIs, chemotherapy, and radiotherapy is beneficial.

Lung Cancer Screening Program In Ambulatory Clinics May Improve Detection Rates

Lung Cancer Screening Program In Ambulatory Clinics May Improve Detection Rates

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A study presented at the 2018 ONS Annual Congress explored the feasibility of an advanced practice nurse-led lung cancer screening program at ambulatory outpatient clinics.

Role and Inhibition of GLI1 Protein in Cancer

Role and Inhibition of GLI1 Protein in Cancer

[Lung Cancer: Targets and Therapy] Italian researchers report on the role of GLI1 in the development of lung cancer, and review its potential as an effective therapy for lung cancer.

Proteomic Biomarker Sensitive, Specific in Distinguishing Benign From Malignant Lung Nodules

Proteomic Biomarker Sensitive, Specific in Distinguishing Benign From Malignant Lung Nodules

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The integrated proteomic classifier performed better than positron emission tomography, validated lung nodule risk models, and physician cancer probability estimates.

Cancer Screening Follow-up: Enabling Timely Diagnosis, Treatment

Cancer Screening Follow-up: Enabling Timely Diagnosis, Treatment

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A review of the literature on follow-up after positive screening results led researchers to a consensus opinion on timing of diagnostic tests for 4 cancers: breast, cervical, colorectal, and lung.

Hope, Optimism Reduce Psychological Distress in Advanced Cancer

Hope, Optimism Reduce Psychological Distress in Advanced Cancer

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A cross-sectional analysis evaluated the impact of hope and optimism on different facets of psychological distress among patients with advanced melanoma, colorectal, lung, or gastrointestinal cancers.

Evolving Role of Radiation Therapy in the Treatment of Mesothelioma

Evolving Role of Radiation Therapy in the Treatment of Mesothelioma

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Research into the potential of radiation therapy in the management of mesothelioma may improve the prognosis, and possibly extend progression-free survival, for patients with this incurable cancer.

Pivot Nurse Improves Patients' Navigation Through Lung Cancer Care

Pivot Nurse Improves Patients' Navigation Through Lung Cancer Care

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Researchers in Montreal presented results of a study on the effects of using a pivot nurse in oncology (PNO) on continuity of care, outcomes, and quality of life for patients with lung cancer at the 2018 European Lung Cancer Congress.

Tobacco Use Data Supports Efforts to Reduce Burden of Smoking-Associated Cancers

Tobacco Use Data Supports Efforts to Reduce Burden of Smoking-Associated Cancers

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Analysis of data from more than 1 million people demonstrates the value of tobacco-use data in tailoring public health programs to prevalence of smokers in local populations.

Vaping May Induce Severe, Negative Effects on Lung Health

Vaping May Induce Severe, Negative Effects on Lung Health

Researchers presented the preliminary results from an ongoing randomized, crossover study evaluating the cardiorespiratory effects of e-cigarettes.

Include Visual Emphysema, COPD Exacerbations When Assessing for Lung Cancer 

Include Visual Emphysema, COPD Exacerbations When Assessing for Lung Cancer 

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Researchers conducted a case-control study that examined independent predictive factors of lung cancer in patients with chronic obstructive pulmonary disease.

CHEST Panel Updates Criteria for Low-Dose CT Screening for Lung Cancer

CHEST Panel Updates Criteria for Low-Dose CT Screening for Lung Cancer

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The panel assembled and updated the above guidelines and recommendations regarding lung cancer screening and low-dose CT screening programs.

SEE-ACBT Method Improves Postsurgical Outcomes in Lung Cancer Resection

SEE-ACBT Method Improves Postsurgical Outcomes in Lung Cancer Resection

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In a quasi-experimental pre-post study, researchers demonstrate the efficacy of the SEE-ACBT rehabilitation method on health-related and cost outcomes in patients with NSCLC who underwent curative lung resection.

Nabilone Improves Cancer-Associated Anorexia in Lung Cancer

Nabilone Improves Cancer-Associated Anorexia in Lung Cancer

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Researchers assessed the efficacy of nabilone for improving symptoms of anorexia in patients with NSCLC. In addition, patient appetite, quality of life, and nutritional status were also assessed.

Excretion of Volatile Organic Compounds Higher in AYAs Using Vaping Products

Excretion of Volatile Organic Compounds Higher in AYAs Using Vaping Products

Excretion of metabolites of acrylonitrile, acrolein, propylene oxide, acrylamide, crotonaldehyde up

E-Cigarette Vapors Found to Contain Toxic Metals

E-Cigarette Vapors Found to Contain Toxic Metals

Study finds metals, including lead, leak from e-cigarette heating coils into inhaled aerosols

Treatment and Outcomes of Non-small-cell Lung Cancer Patients With High Comorbidity

Treatment and Outcomes of Non-small-cell Lung Cancer Patients With High Comorbidity

[Cancer Management and Research] The presence of comorbidities is thought to play a significant role in the decision to treat patients with NSCLC, and this impacts survival.

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