Lung Cancer

Lung Cancer: What Nurse Navigators Need to Know in 2018

Lung Cancer: What Nurse Navigators Need to Know in 2018

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There have been many recent changes in lung cancer, including updated early detection possibilities and changes in diagnostic procedures, reporting, and treatment options. These are reviewed in a presentation at the 2018 ONA Navigation Summit.

Radiation-Induced Esophagitis: A Common, Debilitating Clinical Challenge in Thoracic Radiotherapy

Radiation-Induced Esophagitis: A Common, Debilitating Clinical Challenge in Thoracic Radiotherapy

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A review of current options and ongoing trials for managing ARIE, a common esophageal adverse effect caused by radiotherapy to the thoracic region for lung, breast, or head and neck cancers, or lymphoma.

Ado-trastuzumab Emtansine Effective in HER2 Amplified Non-breast, Non-gastric Cancers

Ado-trastuzumab Emtansine Effective in HER2 Amplified Non-breast, Non-gastric Cancers

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Study results presented at 2018 ASCO Annual Meeting demonstrated effectiveness of ado-trastuzumab emtansine in non-breast non-gastric HER2-amplified cancers.

Response to Rapamycin Analogs but not PD-1 Inhibitors in PTEN-mutated Metastatic Non-small Cell Lung Cancer With High Tumor Mutational Burden

Response to Rapamycin Analogs but not PD-1 Inhibitors in PTEN-mutated Metastatic Non-small Cell Lung Cancer With High Tumor Mutational Burden

[Lung Cancer: Targets and Therapy] This case study demonstrates that genomic profiling may still benefit patients who fail checkpoint inhibitor therapy despite having high tumor mutational burden and PD-L1 positivity.

Lung Cancer Incidence is Higher for Young Women Than Young Men

Lung Cancer Incidence is Higher for Young Women Than Young Men

Researchers observed a decrease in the age-specific incidence of lung cancer among both men and women aged 30 to 54 years over the past two decades; the declines among men were steeper.

Multiple Treatment Modalities for Brain Metastasis in Patients With EGFR-mutant Non-small Cell Lung Cancer

Multiple Treatment Modalities for Brain Metastasis in Patients With EGFR-mutant Non-small Cell Lung Cancer

[OncoTargets and Therapy] Management of brain metastases in patients with EGFR-mutant NSCLC is controversial. In this study, researchers find combination and sequential treatment with EGFR-TKIs, chemotherapy, and radiotherapy is beneficial.

Lung Cancer Screening Program In Ambulatory Clinics May Improve Detection Rates

Lung Cancer Screening Program In Ambulatory Clinics May Improve Detection Rates

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A study presented at the 2018 ONS Annual Congress explored the feasibility of an advanced practice nurse-led lung cancer screening program at ambulatory outpatient clinics.

Role and Inhibition of GLI1 Protein in Cancer

Role and Inhibition of GLI1 Protein in Cancer

[Lung Cancer: Targets and Therapy] Italian researchers report on the role of GLI1 in the development of lung cancer, and review its potential as an effective therapy for lung cancer.

Proteomic Biomarker Sensitive, Specific in Distinguishing Benign From Malignant Lung Nodules

Proteomic Biomarker Sensitive, Specific in Distinguishing Benign From Malignant Lung Nodules

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The integrated proteomic classifier performed better than positron emission tomography, validated lung nodule risk models, and physician cancer probability estimates.

Cancer Screening Follow-up: Enabling Timely Diagnosis, Treatment

Cancer Screening Follow-up: Enabling Timely Diagnosis, Treatment

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A review of the literature on follow-up after positive screening results led researchers to a consensus opinion on timing of diagnostic tests for 4 cancers: breast, cervical, colorectal, and lung.

Hope, Optimism Reduce Psychological Distress in Advanced Cancer

Hope, Optimism Reduce Psychological Distress in Advanced Cancer

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A cross-sectional analysis evaluated the impact of hope and optimism on different facets of psychological distress among patients with advanced melanoma, colorectal, lung, or gastrointestinal cancers.

Evolving Role of Radiation Therapy in the Treatment of Mesothelioma

Evolving Role of Radiation Therapy in the Treatment of Mesothelioma

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Research into the potential of radiation therapy in the management of mesothelioma may improve the prognosis, and possibly extend progression-free survival, for patients with this incurable cancer.

Pivot Nurse Improves Patients' Navigation Through Lung Cancer Care

Pivot Nurse Improves Patients' Navigation Through Lung Cancer Care

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Researchers in Montreal presented results of a study on the effects of using a pivot nurse in oncology (PNO) on continuity of care, outcomes, and quality of life for patients with lung cancer at the 2018 European Lung Cancer Congress.

Tobacco Use Data Supports Efforts to Reduce Burden of Smoking-Associated Cancers

Tobacco Use Data Supports Efforts to Reduce Burden of Smoking-Associated Cancers

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Analysis of data from more than 1 million people demonstrates the value of tobacco-use data in tailoring public health programs to prevalence of smokers in local populations.

Vaping May Induce Severe, Negative Effects on Lung Health

Vaping May Induce Severe, Negative Effects on Lung Health

Researchers presented the preliminary results from an ongoing randomized, crossover study evaluating the cardiorespiratory effects of e-cigarettes.

Include Visual Emphysema, COPD Exacerbations When Assessing for Lung Cancer 

Include Visual Emphysema, COPD Exacerbations When Assessing for Lung Cancer 

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Researchers conducted a case-control study that examined independent predictive factors of lung cancer in patients with chronic obstructive pulmonary disease.

CHEST Panel Updates Criteria for Low-Dose CT Screening for Lung Cancer

CHEST Panel Updates Criteria for Low-Dose CT Screening for Lung Cancer

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The panel assembled and updated the above guidelines and recommendations regarding lung cancer screening and low-dose CT screening programs.

SEE-ACBT Method Improves Postsurgical Outcomes in Lung Cancer Resection

SEE-ACBT Method Improves Postsurgical Outcomes in Lung Cancer Resection

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In a quasi-experimental pre-post study, researchers demonstrate the efficacy of the SEE-ACBT rehabilitation method on health-related and cost outcomes in patients with NSCLC who underwent curative lung resection.

Nabilone Improves Cancer-Associated Anorexia in Lung Cancer

Nabilone Improves Cancer-Associated Anorexia in Lung Cancer

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Researchers assessed the efficacy of nabilone for improving symptoms of anorexia in patients with NSCLC. In addition, patient appetite, quality of life, and nutritional status were also assessed.

Excretion of Volatile Organic Compounds Higher in AYAs Using Vaping Products

Excretion of Volatile Organic Compounds Higher in AYAs Using Vaping Products

Excretion of metabolites of acrylonitrile, acrolein, propylene oxide, acrylamide, crotonaldehyde up

E-Cigarette Vapors Found to Contain Toxic Metals

E-Cigarette Vapors Found to Contain Toxic Metals

Study finds metals, including lead, leak from e-cigarette heating coils into inhaled aerosols

Treatment and Outcomes of Non-small-cell Lung Cancer Patients With High Comorbidity

Treatment and Outcomes of Non-small-cell Lung Cancer Patients With High Comorbidity

[Cancer Management and Research] The presence of comorbidities is thought to play a significant role in the decision to treat patients with NSCLC, and this impacts survival.

Exercise, Fitness Significantly Decrease After Advanced Lung Cancer Diagnosis

Exercise, Fitness Significantly Decrease After Advanced Lung Cancer Diagnosis

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Using MVIC and 6MWT, researchers sought to determine if patients' exercise behaviors changed after a diagnosis of advanced lung cancer.

Exercise Before Lung Cancer Surgery Greatly Reduces Complications

Exercise Before Lung Cancer Surgery Greatly Reduces Complications

Researchers conducted a systematic literature search to identify studies investigating the effectiveness of preoperative exercise on outcomes among oncology patients undergoing surgery.

Efficacy and Safety of COX-2 Inhibitors for Advanced Non-small-cell Lung Cancer With Chemotherapy: A Meta-analysis

Efficacy and Safety of COX-2 Inhibitors for Advanced Non-small-cell Lung Cancer With Chemotherapy: A Meta-analysis

[OncoTargets and Therapy] This meta-analysis assesses the efficacy and safety profile of COX-2 inhibitors in patients with advanced non-small-cell lung cancer.

Lung Cancer Screening: Risk-Targeting Approach vs NLST Eligibility Criteria

Lung Cancer Screening: Risk-Targeting Approach vs NLST Eligibility Criteria

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In a review of data from the NLST, researchers sought to determine if a risk-targeting approach would more efficiently select high-risk persons for lung cancer screening than the eligibility criteria defined by the NLST.

Platinum-Based Chemotherapies Demonstrate Similar Risk for Thromboembolic Events

Platinum-Based Chemotherapies Demonstrate Similar Risk for Thromboembolic Events

Platinum-based chemotherapy agents for lung cancer may increase the risk for thromboembolism.

Documentation of Cancer Risk in Indeterminate Pulmonary Nodules Inconsistent

Documentation of Cancer Risk in Indeterminate Pulmonary Nodules Inconsistent

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Qualitative risk statements of malignancy for indeterminate pulmonary nodules are imprecise, highly variable, and should be replaced by a standard scale.

Lung Cancer Screening More Efficient for Those at Higher Risk

Lung Cancer Screening More Efficient for Those at Higher Risk

Initial screens were least effective and least efficient for veterans with lowest lung cancer risk, according to this study.

Nearly One Third of Veterans Report Current Tobacco Use

Nearly One Third of Veterans Report Current Tobacco Use

Researchers found that nearly one third of veterans reported current use of a tobacco product, with cigarettes being most frequently used.

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